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ONTOLOGY REPORT - ANNOTATIONS

Term:coenzyme A biosynthetic process
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Accession:GO:0015937 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
Synonyms:exact_synonym: CoA biosynthesis;   coenzyme A anabolism;   coenzyme A biosynthesis;   coenzyme A formation;   coenzyme A synthesis
 alt_id: GO:0006764
 xref: MetaCyc:COA-PWY;   MetaCyc:PANTOSYN-PWY;   MetaCyc:PWY-4221


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coenzyme A biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO (PMID:17371050) RGD PMID:17371050 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
G Acot7 acyl-CoA thioesterase 7 involved_in ISO
IEA		 (PMID:10578051)
GO_REF:0000107		 RGD
Ensembl		 PMID:10578051 GO_REF:0000107 NCBI chr 5:162,686,562...162,779,309
Ensembl chr 5:162,684,645...162,779,309 		JBrowse link
G Coasy Coenzyme A synthase involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:11923312)
(MGI:2181228|PMID:11980892)
PMID:21873635		 RGD PMID:11923312 PMID:11980892 PMID:21873635 MGI:2181228, RGD:13792537 NCBI chr10:86,014,566...86,018,849
Ensembl chr10:86,014,597...86,018,841 		JBrowse link
G Dcakd dephospho-CoA kinase domain containing involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:87,957,738...87,989,002
Ensembl chr10:87,957,740...87,980,054 		JBrowse link
G Pank1 pantothenate kinase 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2176050|MGI:4462018 (MGI:4461354|PMID:20559429), (MGI:5446555|PMID:22815849)
(MGI:3607004|PMID:16040613)
PMID:21873635		 RGD PMID:16040613 PMID:20559429 PMID:22815849 PMID:21873635 MGI:3607004 MGI:4461354 MGI:5446555, RGD:13792537 NCBI chr 1:232,324,718...232,395,445
Ensembl chr 1:232,328,430...232,396,829 		JBrowse link
G Pank2 pantothenate kinase 2 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2176050|MGI:5446719 (MGI:5446555|PMID:22815849)
PMID:21873635		 RGD PMID:22815849 PMID:21873635 MGI:5446555, RGD:13792537 NCBI chr 3:118,483,382...118,519,551
Ensembl chr 3:118,483,444...118,518,320 		JBrowse link
G Pank3 pantothenate kinase 3 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:20797618), (PMID:30927326)
(MGI:3607004|PMID:16040613)
PMID:21873635		 RGD PMID:16040613 PMID:20797618 PMID:30927326 PMID:21873635 MGI:3607004, RGD:13792537 NCBI chr10:20,229,129...20,252,955
Ensembl chr10:20,229,129...20,252,955 		JBrowse link
G Pank4 pantothenate kinase 4 involved_in IEA
IBA		 GO_REF:0000104
PMID:21873635		 UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 5:165,525,340...165,542,139
Ensembl chr 5:165,525,402...165,542,135 		JBrowse link
G Ppcdc phosphopantothenoylcysteine decarboxylase involved_in IBA
ISO		 PMID:21873635
(PMID:11923312)		 RGD PMID:11923312 PMID:21873635 RGD:13792537 NCBI chr 8:57,815,195...57,842,863
Ensembl chr 8:57,815,195...58,000,570 		JBrowse link
G Ppcs phosphopantothenoylcysteine synthetase involved_in ISO
IBA		 (PMID:11923312), (PMID:29754768)
PMID:21873635		 RGD PMID:11923312 PMID:29754768 PMID:21873635 RGD:13792537 NCBI chr 5:133,023,077...133,026,899
Ensembl chr 5:133,023,121...133,026,933 		JBrowse link
G Taf9 TATA-box binding protein associated factor 9 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:31,794,316...31,798,324
Ensembl chr 2:31,794,142...31,798,769 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19818
    metabolic process 12096
      cellular metabolic process 7496
        cellular aromatic compound metabolic process 3078
          purine-containing compound metabolic process 468
            purine nucleoside bisphosphate metabolic process 114
              coenzyme A metabolic process 17
                coenzyme A biosynthetic process 11
                  regulation of coenzyme A biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 19818
    metabolic process 12096
      cellular metabolic process 7496
        cellular aromatic compound metabolic process 3078
          nucleobase-containing compound metabolic process 2826
            nucleobase-containing small molecule metabolic process 573
              nucleoside phosphate metabolic process 500
                nucleotide metabolic process 489
                  purine nucleotide metabolic process 433
                    purine ribonucleotide metabolic process 338
                      coenzyme A metabolic process 17
                        coenzyme A biosynthetic process 11
                          regulation of coenzyme A biosynthetic process 0
paths to the root