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ONTOLOGY REPORT - ANNOTATIONS

Term:coenzyme A metabolic process
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Accession:GO:0015936 term browser browse the term
Definition:The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
Synonyms:exact_synonym: CoA metabolism;   coenzyme A metabolism
 alt_id: GO:0006763


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coenzyme A metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:103,008,564...103,034,697
Ensembl chr11:106,483,563...106,509,787 		JBrowse link
G CROT carnitine O-octanoyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:79,339,498...79,393,676
Ensembl chr 7:92,989,868...93,043,832 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:39,936,630...39,961,519
Ensembl chr 5:40,548,919...40,573,785 		JBrowse link
G MCCC2 methylcrotonyl-CoA carboxylase subunit 2 ISO RGD PMID:3995077 RGD:2316862 NCBI chr 5:43,650,993...43,724,877
Ensembl chr 5:44,298,650...44,369,106 		JBrowse link
coenzyme A biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:103,008,564...103,034,697
Ensembl chr11:106,483,563...106,509,787 		JBrowse link
G ACOT7 acyl-CoA thioesterase 7 involved_in ISO (PMID:10578051) BHF-UCL PMID:10578051 NCBI chr 1:5,030,488...5,154,800 JBrowse link
G COASY Coenzyme A synthase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11980892) Ensembl
MGI
TreeGrafter
InterPro		 PMID:11980892 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr17:14,750,246...14,754,417
Ensembl chr17:14,973,662...14,977,797 		JBrowse link
G DCAKD dephospho-CoA kinase domain containing involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr17:12,266,199...12,299,502
Ensembl chr17:12,440,194...12,473,099 		JBrowse link
G PANK1 pantothenate kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20559429), (PMID:22815849) InterPro
MGI
TreeGrafter		 PMID:20559429 PMID:22815849 GO_REF:0000002 GO_REF:0000118 NCBI chr10:86,302,702...86,428,635
Ensembl chr10:89,847,888...89,912,765 		JBrowse link
G PANK2 pantothenate kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22815849) InterPro
MGI
TreeGrafter
Ensembl		 PMID:22815849 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr20:3,924,054...3,959,393
Ensembl chr20:3,723,211...3,757,748 		JBrowse link
G PANK3 pantothenate kinase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16040613) InterPro
MGI
TreeGrafter
Ensembl		 PMID:16040613 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:163,913,842...163,944,939
Ensembl chr 5:170,685,413...170,709,211 		JBrowse link
G PANK4 pantothenate kinase 4 (inactive) involved_in IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 GO_REF:0000118 NCBI chr 1:1,238,821...1,259,139
Ensembl chr 1:2,378,116...2,395,738 		JBrowse link
G PPCDC phosphopantothenoylcysteine decarboxylase involved_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr15:53,963,001...54,001,550
Ensembl chr15:73,579,583...73,606,834 		JBrowse link
G PPCS phosphopantothenoylcysteine synthetase involved_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr 1:41,756,403...41,773,430
Ensembl chr 1:43,136,720...43,140,620 		JBrowse link
G SGPL1 sphingosine-1-phosphate lyase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:67,286,349...67,351,574
Ensembl chr10:69,812,092...69,876,438 		JBrowse link
coenzyme A catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT19 nudix hydrolase 19 involved_in ISO (MGI:6157214|PMID:29378847) UniProt PMID:29378847 MGI:6157214 NCBI chr19:29,610,390...29,632,778 JBrowse link
G NUDT7 nudix hydrolase 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11415433) TreeGrafter
MGI		 PMID:11415433 GO_REF:0000118 NCBI chr16:58,312,917...58,333,256
Ensembl chr16:77,747,863...77,801,651 		JBrowse link
G VNN1 vanin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:130,459,268...130,491,167
Ensembl chr 6:134,566,117...134,598,784 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    metabolic process 10303
      organic substance metabolic process 9869
        organonitrogen compound metabolic process 4927
          purine-containing compound metabolic process 512
            purine nucleoside bisphosphate metabolic process 110
              coenzyme A metabolic process 17
                coenzyme A biosynthetic process + 11
                coenzyme A catabolic process 3
Path 2
Term Annotations click to browse term
  biological_process 16440
    metabolic process 10303
      organic substance metabolic process 9869
        organic cyclic compound metabolic process 5562
          nucleobase-containing compound metabolic process 5109
            nucleobase-containing small molecule metabolic process 605
              nucleoside phosphate metabolic process 539
                nucleotide metabolic process 533
                  purine nucleotide metabolic process 479
                    purine ribonucleotide metabolic process 404
                      coenzyme A metabolic process 17
                        coenzyme A biosynthetic process + 11
                        coenzyme A catabolic process 3
paths to the root