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ONTOLOGY REPORT - ANNOTATIONS

Term:ABC-type heme transporter activity
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Accession:GO:0015439 term browser browse the term
Definition:Catalysis of the reaction: ATP + H2O + heme(in) = ADP + phosphate + heme(out).
Synonyms:exact_synonym: ATP-dependent heme transmembrane transporter activity;   haem-transporting ATPase activity;   heme-transporting ATPase activity
 narrow_synonym: heme ABC transporter
 related_synonym: ATPase-coupled heme transmembrane transporter activity;   ATPase-coupled heme transporter activity;   protoheme IX ABC transporter activity
 alt_id: GO:0103115
 xref: EC:7.6.2.5;   MetaCyc:3.6.3.41-RXN;   RHEA:19261;   Reactome:R-HSA-1369065 "ABCB6 transports porphyrin from cytosol to mitchondrial matrix";   Reactome:R-HSA-382560 "ABC7, mABC1 and mABC2 mediate heme transport";   Reactome:R-HSA-5683355 "Defective ABCB6 does not transport porphyrin from cytosol into mitochondria matrix";   Reactome:R-HSA-917979 "ABCG2 tetramer transports heme from cytosol to extracellular region"


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ABC-type heme transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP binding cassette subfamily B member 6 enables ISO
IBA
IEA		 (PMID:17006453)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000003		 RGD
GO_Central
Ensembl
UniProt		 PMID:17006453 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:84,117,222...84,125,939
Ensembl chr 9:76,668,554...76,676,924 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21102
    transporter activity 1395
      transmembrane transporter activity 1278
        heme transmembrane transporter activity 8
          ABC-type heme transporter activity 1
Path 2
Term Annotations click to browse term
  molecular_function 21102
    transporter activity 1395
      transmembrane transporter activity 1278
        active transmembrane transporter activity 449
          primary active transmembrane transporter activity 168
            ATPase-coupled transmembrane transporter activity 119
              ABC-type transporter activity 56
                ABC-type heme transporter activity 1
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