ABC-type peptide antigen transporter activity - Ontology Report

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Term:	ABC-type peptide antigen transporter activity	go back to main search page
Accession:	GO:0015433	browse the term
Definition:	Catalysis of the reaction: peptide antigen(in) + ATP = peptide antigen(out) + ADP + phosphate.
Synonyms:	exact_synonym:	ATP-dependent peptide antigen transmembrane transporter activity; major histocompatibility peptide transporter activity; peptide antigen-transporting ATPase activity
	narrow_synonym:	peptide antigen ABC transporter
	broad_synonym:	peptide antigen transporter activity
	related_synonym:	ATPase-coupled peptide antigen transmembrane transporter activity
	xref:	EC:7.4.2.14; MetaCyc:3.6.3.43-RXN; RHEA:65972; TC:3.A.1.209.1; reactome:R-HSA-1236949 "Translocation of antigenic peptides back to phagosomes via TAP"; reactome:R-HSA-983144 "Transport of Antigen peptide in to ER"

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Genes (2)

ABC-type peptide antigen transporter activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Tap1

transporter 1, ATP binding cassette subfamily B member

enables
contributes_to

TAS
IEA
ISO
IBA

GO_REF:0000107
(PMID:12645939), (PMID:8342042)
(PMID:11133832), (PMID:17418234), (PMID:25377891), (PMID:25656091)
UniProtKB:Q03519 (PMID:7673167)
GO_REF:0000033

Ensembl
RGD
GO_Central

PMID:7673167 PMID:8342042 PMID:11133832 PMID:12645939 PMID:17418234 More...

GO_REF:0000033 GO_REF:0000107, RGD:1300480

NCBI chr20:4,658,171...4,668,543
Ensembl chr20:4,656,263...4,666,901

Tap2

transporter 2, ATP binding cassette subfamily B member

enables
contributes_to

TAS
ISO
IEA

(PMID:1538751), (PMID:25377891), (PMID:25656091)
GO_REF:0000107
UniProtKB:Q03518 (PMID:7673167)

RGD
Ensembl

PMID:1538751 PMID:7673167 PMID:25377891 PMID:25656091 PMID:14622282

GO_REF:0000107, RGD:1300480

NCBI chr20:4,638,257...4,652,296
Ensembl chr20:4,636,357...4,650,407

Term paths to the root

Path 1
Term	Annotations
molecular_function	21054
ATP-dependent activity	633
ATPase-coupled transmembrane transporter activity	119
ABC-type transporter activity	56
ABC-type peptide transporter activity	3
ABC-type peptide antigen transporter activity	2
Path 2
Term	Annotations
molecular_function	21054
transporter activity	1274
transmembrane transporter activity	1165
active transmembrane transporter activity	449
primary active transmembrane transporter activity	168
ATPase-coupled transmembrane transporter activity	119
ABC-type transporter activity	56
ABC-type peptide transporter activity	3
ABC-type peptide antigen transporter activity	2

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ONTOLOGY REPORT - ANNOTATIONS