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ONTOLOGY REPORT - ANNOTATIONS


Term:oxoglutarate:malate antiporter activity
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Accession:GO:0015367 term browser browse the term
Definition:Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: oxoglutarate(out) + malate(in) = oxoglutarate(in) + malate(out).
Synonyms:exact_synonym: 2-oxoglutarate/malate carrier protein
 xref: Reactome:R-HSA-198440 "SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane";   Reactome:R-HSA-376851 "SLC25A11 exchanges 2-OG and MAL"



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oxoglutarate:malate antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a11 solute carrier family 25 member 11 enables IEA
ISO
GO_REF:0000107
(PMID:35507647)
Ensembl
RGD
PMID:35507647 GO_REF:0000107 NCBI chr10:55,357,590...55,360,441
Ensembl chr10:55,357,597...55,360,410
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Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21087
    transporter activity 1269
      transmembrane transporter activity 1162
        active transmembrane transporter activity 449
          secondary active transmembrane transporter activity 293
            antiporter activity 131
              oxoglutarate:malate antiporter activity 1
Path 2
Term Annotations click to browse term
  molecular_function 21087
    transporter activity 1269
      transmembrane transporter activity 1162
        organic acid transmembrane transporter activity 193
          carboxylic acid transmembrane transporter activity 192
            dicarboxylic acid transmembrane transporter activity 31
              alpha-ketoglutarate transmembrane transporter activity 6
                oxoglutarate:malate antiporter activity 1
paths to the root