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ONTOLOGY REPORT - ANNOTATIONS


Term:sterol transporter activity
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Accession:GO:0015248 term browser browse the term
Definition:Enables the directed movement of sterols into, out of or within a cell, or between cells. Sterol are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
Synonyms:xref: RHEA:39747;   Reactome:R-HSA-5679101 "Defective ABCG8 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region";   Reactome:R-HSA-5679145 "Defective ABCG5 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region";   reactome:R-HSA-265783 "ABCG5:ABCG8 transports sterols from cytosol to extracellular region";   reactome:R-HSA-5250531 "ARV1 transports CHOL from ER membrane to plasma membrane";   reactome:R-HSA-8867667 "OSBPs transport 25OH-CHOL from ER membrane to plasma membrane";   reactome:R-HSA-8868402 "OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane"



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sterol transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Osbp oxysterol binding protein enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:208,888,697...208,918,511
Ensembl chr 1:208,887,895...208,918,506
JBrowse link
G Osbp2 oxysterol binding protein 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:78,585,088...78,746,785
Ensembl chr14:78,585,089...78,746,786
JBrowse link
G Osbpl10 oxysterol binding protein-like 10 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:114,661,050...114,918,664
Ensembl chr 8:114,660,743...114,918,625
JBrowse link
G Osbpl11 oxysterol binding protein-like 11 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:67,533,669...67,616,795
Ensembl chr11:67,533,672...67,596,444
JBrowse link
G Osbpl1a oxysterol binding protein-like 1A enables IBA
IEA
GO_REF:0000033
GO_REF:0000118
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000118 NCBI chr18:3,904,006...4,094,635
Ensembl chr18:3,904,006...4,094,585
JBrowse link
G Osbpl2 oxysterol binding protein-like 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:167,210,945...167,256,219
Ensembl chr 3:167,210,832...167,256,219
JBrowse link
G Osbpl3 oxysterol binding protein-like 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:79,346,583...79,523,523
Ensembl chr 4:79,350,349...79,523,393
JBrowse link
G Osbpl5 oxysterol binding protein-like 5 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:198,862,071...198,916,469
Ensembl chr 1:198,862,055...198,916,469
JBrowse link
G Osbpl6 oxysterol binding protein-like 6 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:61,343,776...61,541,170
Ensembl chr 3:61,343,809...61,537,102
JBrowse link
G Osbpl7 oxysterol binding protein-like 7 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:82,035,995...82,053,566
Ensembl chr10:82,036,042...82,053,557
JBrowse link
G Osbpl8 oxysterol binding protein-like 8 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:46,596,944...46,749,888
Ensembl chr 7:46,596,983...46,749,888
JBrowse link
G Osbpl9 oxysterol binding protein-like 9 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:123,819,106...123,962,213
Ensembl chr 5:123,819,104...123,962,196
JBrowse link
ABC-type sterol transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 enables ISO
IBA
(PMID:17408620)
GO_REF:0000033
RGD
GO_Central
PMID:17408620 GO_REF:0000033 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Abcg4 ATP binding cassette subfamily G member 4 enables ISS
IBA
IEA
ISO
GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(MGI:3047008|PMID:15210959)
UniProt
GO_Central
Ensembl
RGD
PMID:15210959 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:3047008 NCBI chr 8:44,611,187...44,629,818
Ensembl chr 8:44,611,187...44,626,881
JBrowse link
cholesterol transfer activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 enables ISO (PMID:12084722)
(MGI:3513719|PMID:15520449)
RGD PMID:12084722 PMID:15520449 MGI:3513719 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 enables ISO (PMID:15994327) RGD PMID:15994327 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 contributes_to ISO UniProtKB:Q99PE8 (PMID:14504269)
(MGI:2681374|PMID:14504269)
RGD PMID:14504269 MGI:2681374 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 contributes_to ISO
IBA
UniProtKB:Q9DBM0 (PMID:14504269)
(MGI:2681374|PMID:14504269)
GO_REF:0000033
RGD
GO_Central
PMID:14504269 GO_REF:0000033 MGI:2681374 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
JBrowse link
G Apoa1 apolipoprotein A1 contributes_to
enables
IDA
ISO
IEA
IBA
(PMID:9651324)
(PMID:15464323)
(MGI:3056863|PMID:15269218)
GO_REF:0000107
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:9651324 PMID:15269218 PMID:15464323 PMID:11773045 PMID:1537840 GO_REF:0000033 GO_REF:0000107 MGI:3056863, RGD:1298673, RGD:1626399 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa2 apolipoprotein A2 contributes_to
enables
IDA
ISO
IBA
(PMID:9651324)
GO_REF:0000033
RGD
GO_Central
PMID:9651324 PMID:1537840 GO_REF:0000033, RGD:1626399 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoa4 apolipoprotein A4 enables IEA
ISO
IBA
GO_REF:0000107
(PMID:1935934)
GO_REF:0000033
Ensembl
RGD
GO_Central
PMID:1935934 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoa5 apolipoprotein A5 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
JBrowse link
G Apob apolipoprotein B enables ISO
IEA
IBA
(PMID:15797858)
GO_REF:0000107
GO_REF:0000118
GO_REF:0000033
RGD
Ensembl
TreeGrafter
GO_Central
PMID:15797858 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Apoe apolipoprotein E enables ISO
IBA
(MGI:3056863|PMID:15269218)
GO_REF:0000033
RGD
GO_Central
PMID:15269218 GO_REF:0000033 MGI:3056863 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Gramd1a GRAM domain containing 1A enables IEA
ISS
ISO
IBA
GO_REF:0000107
GO_REF:0000024
(MGI:6242147|PMID:30220461)
GO_REF:0000118
GO_REF:0000033
Ensembl
UniProt
RGD
TreeGrafter
GO_Central
PMID:30220461 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:6242147 NCBI chr 1:86,367,001...86,393,348
Ensembl chr 1:86,367,001...86,393,336
JBrowse link
G Gramd1b GRAM domain containing 1B enables ISO
IBA
(MGI:6242147|PMID:30220461)
GO_REF:0000033
RGD
GO_Central
PMID:30220461 GO_REF:0000033 MGI:6242147 NCBI chr 8:40,654,492...40,893,869
Ensembl chr 8:40,659,182...40,893,925
JBrowse link
G Gramd1c GRAM domain containing 1C enables ISO (MGI:6242147|PMID:30220461) RGD PMID:30220461 MGI:6242147 NCBI chr11:56,633,229...56,718,570
Ensembl chr11:56,633,227...56,718,570
JBrowse link
G Mttp microsomal triglyceride transfer protein enables IDA
ISO
PMID:15897609
(PMID:15897609), (PMID:16478722), (PMID:8876250)
(MGI:6467714|PMID:15897609)
RGD PMID:8876250 PMID:15897609 PMID:16478722 PMID:15897609 MGI:6467714, RGD:39458034 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
JBrowse link
G Npc2 NPC intracellular cholesterol transporter 2 enables ISO (PMID:18772377), (PMID:25339683), (PMID:27238017) RGD PMID:18772377 PMID:25339683 PMID:27238017 NCBI chr 6:104,397,239...104,418,161
Ensembl chr 6:104,378,644...104,418,155
JBrowse link
G Osbpl2 oxysterol binding protein-like 2 enables ISO (PMID:30581148) RGD PMID:30581148 NCBI chr 3:167,210,945...167,256,219
Ensembl chr 3:167,210,832...167,256,219
JBrowse link
G Pltp phospholipid transfer protein enables ISO (MGI:1332889|PMID:10079112) RGD PMID:10079112 MGI:1332889 NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647
JBrowse link
G Scp2 sterol carrier protein 2 enables IDA
ISO
PMID:8063752
(PMID:7642518)
RGD PMID:7642518 PMID:8063752 PMID:8063752 RGD:9850162, RGD:9850162 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
JBrowse link
G Star steroidogenic acute regulatory protein TAS RGD PMID:11861536 RGD:634518 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Stard3 StAR-related lipid transfer domain containing 3 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:83,357,329...83,379,873
Ensembl chr10:83,357,359...83,550,976
JBrowse link
G Stard4 StAR-related lipid transfer domain containing 4 enables ISO
IBA
(PMID:18403318)
GO_REF:0000033
RGD
GO_Central
PMID:18403318 GO_REF:0000033 NCBI chr18:24,814,683...24,830,024
Ensembl chr18:24,817,107...24,830,024
JBrowse link
G Stard5 StAR-related lipid transfer domain containing 5 enables ISO
IBA
(PMID:18403318)
GO_REF:0000033
RGD
GO_Central
PMID:18403318 GO_REF:0000033 NCBI chr 1:137,606,151...137,616,017
Ensembl chr 1:137,606,177...137,616,469
JBrowse link
sterol transfer activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Osbp oxysterol binding protein enables ISO (PMID:24209621) RGD PMID:24209621 NCBI chr 1:208,888,697...208,918,511
Ensembl chr 1:208,887,895...208,918,506
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20893
    transporter activity 1260
      lipid transporter activity 183
        sterol transporter activity 34
          ABC-type sterol transporter activity 2
          sterol transfer activity + 23
paths to the root