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ONTOLOGY REPORT - ANNOTATIONS


Term:malate transmembrane transporter activity
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Accession:GO:0015140 term browser browse the term
Definition:Enables the transfer of malate from one side of a membrane to the other. Malate is a chiral hydroxydicarboxylic acid, hydroxybutanedioic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
Synonyms:related_synonym: dicarboxylate (succinate/fumarate/malate) antiporter activity



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malate transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a10 solute carrier family 25 member 10 enables IDA
ISO
IBA
(PMID:16027120)
GO_REF:0000033
RGD
GO_Central
PMID:16027120 PMID:9733776 GO_REF:0000033, RGD:634162 NCBI chr10:106,264,396...106,271,895
Ensembl chr10:105,765,372...105,773,556
JBrowse link
G Ucp2 uncoupling protein 2 enables ISS
ISO
GO_REF:0000024
(PMID:24395786)
UniProt
RGD
PMID:24395786 GO_REF:0000024 NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
oxoglutarate:malate antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a11 solute carrier family 25 member 11 enables IEA
ISO
GO_REF:0000107
(PMID:35507647)
Ensembl
RGD
PMID:35507647 GO_REF:0000107 NCBI chr10:55,357,590...55,360,441
Ensembl chr10:55,357,597...55,360,410
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  molecular_function 21090
    transporter activity 1270
      transmembrane transporter activity 1162
        organic acid transmembrane transporter activity 193
          carboxylic acid transmembrane transporter activity 192
            dicarboxylic acid transmembrane transporter activity 31
              malate transmembrane transporter activity 3
                malate:proton symporter activity 0
                malate:sodium symporter activity 0
                oxoglutarate:malate antiporter activity 1
paths to the root