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ONTOLOGY REPORT - ANNOTATIONS


Term:alpha-ketoglutarate transmembrane transporter activity
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Accession:GO:0015139 term browser browse the term
Definition:Enables the transfer of alpha-ketoglutarate from one side of a membrane to the other. Alpha-ketoglutarate (or oxoglutarate) is a compound with important roles in carbohydrate and amino acid metabolism, especially in transamination reactions and as a component of the TCA cycle.
Synonyms:exact_synonym: 2-oxoglutarate transporter activity
 xref: reactome:R-HSA-372480 "2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix]"



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alpha-ketoglutarate transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc13a2 solute carrier family 13 member 2 enables ISO
IDA
IBA
(PMID:10894787)
PMID:9691021
GO_REF:0000033
RGD
GO_Central
PMID:10894787 PMID:9691021 GO_REF:0000033, RGD:153298959 NCBI chr10:63,291,813...63,319,127 JBrowse link
G Slc13a3 solute carrier family 13 member 3 enables IEA
ISO
GO_REF:0000107
(PMID:30635937)
Ensembl
RGD
PMID:30635937 GO_REF:0000107 NCBI chr 3:154,141,878...154,204,604 JBrowse link
G Slc22a6 solute carrier family 22 member 6 enables ISS
ISO
GO_REF:0000024
(PMID:9950961)
UniProt
RGD
PMID:9950961 GO_REF:0000024 NCBI chr 1:205,522,579...205,531,179 JBrowse link
G Slc22a7 solute carrier family 22 member 7 enables ISS
ISO
GO_REF:0000024
(PMID:11327718)
(PMID:12065749)
UniProt
RGD
PMID:11327718 PMID:12065749 GO_REF:0000024 NCBI chr 9:14,547,073...14,554,354 JBrowse link
G Slc25a11 solute carrier family 25 member 11 IMP RGD PMID:12939596 RGD:1299466 NCBI chr10:55,856,209...55,859,060 JBrowse link
G Slc25a21 solute carrier family 25 member 21 enables ISO
IEA
(PMID:11083877), (PMID:29517768)
GO_REF:0000107
RGD
Ensembl
PMID:11083877 PMID:29517768 GO_REF:0000107 NCBI chr 6:74,203,439...74,702,902 JBrowse link
oxoglutarate:malate antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a11 solute carrier family 25 member 11 enables IEA
ISO
GO_REF:0000107
(PMID:35507647)
Ensembl
RGD
PMID:35507647 GO_REF:0000107 NCBI chr10:55,856,209...55,859,060 JBrowse link

Term paths to the root
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Term Annotations click to browse term
  molecular_function 21086
    transporter activity 1269
      transmembrane transporter activity 1162
        organic anion transmembrane transporter activity 281
          carboxylic acid transmembrane transporter activity 192
            dicarboxylic acid transmembrane transporter activity 31
              alpha-ketoglutarate transmembrane transporter activity 6
                alpha-ketoglutarate:proton symporter activity 0
                oxoglutarate:malate antiporter activity 1
paths to the root