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ONTOLOGY REPORT - ANNOTATIONS


Term:organic cation transmembrane transporter activity
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Accession:GO:0015101 term browser browse the term
Definition:Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage.
Synonyms:xref: reactome:R-HSA-2161500 "abacavir [extracellular] => abacavir [cytosol]";   reactome:R-HSA-549129 "OCT1 transports organic cations into hepatic cells";   reactome:R-HSA-549279 "OCT2 mediates tubular uptake of organic cations in the kidney";   reactome:R-HSA-549304 "OCT3 mediates renal clearance of organic cations";   reactome:R-HSA-549322 "OCT1 transports organic cations out of hepatic cells";   reactome:R-HSA-561054 "OCT2 mediates tubular secretion of organic cations in the kidney";   reactome:R-HSA-561072 "OCT3 mediates renal uptake of organic cations"


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organic cation transmembrane transporter activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc22a1 solute carrier family 22 member 1 JBrowse link 1 48,273,639 48,300,645 RGD:634159
RGD:13792537
RGD:7243886
RGD:1624291
G Slc22a16 solute carrier family 22 member 16 JBrowse link 20 45,658,398 45,669,192 RGD:1624291
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:1624291
RGD:13792537
RGD:1600115
RGD:7243886
G Slc22a3 solute carrier family 22 member 3 JBrowse link 1 48,433,079 48,521,261 RGD:70010
RGD:13792537
RGD:1624291
G Slc22a4 solute carrier family 22 member 4 JBrowse link 10 39,334,972 39,373,508 RGD:633351
G Slc7a8 solute carrier family 7 member 8 JBrowse link 15 33,369,245 33,428,942 RGD:1624291
RGD:1600115
acetylcholine transmembrane transporter activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc18a3 solute carrier family 18 member A3 JBrowse link 16 8,682,668 8,685,529 RGD:61752
RGD:13792537
G Slc22a1 solute carrier family 22 member 1 JBrowse link 1 48,273,639 48,300,645 RGD:2317432
acyl carnitine transmembrane transporter activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc25a20 solute carrier family 25 member 20 JBrowse link 8 117,455,308 117,476,762 RGD:1624291
G Slc25a29 solute carrier family 25 member 29 JBrowse link 6 132,736,964 132,747,912 RGD:1624291
RGD:13792537
RGD:1600115
G Slc25a45 solute carrier family 25, member 45 JBrowse link 1 221,236,817 221,244,564 RGD:13792537
G Slc25a47 solute carrier family 25, member 47 JBrowse link 6 132,762,306 132,767,940 RGD:13792537
G Slc25a48 solute carrier family 25, member 48 JBrowse link 17 8,567,014 8,608,213 RGD:13792537
AMP transmembrane transporter activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc25a17 solute carrier family 25 member 17 JBrowse link 7 122,539,293 122,581,777 RGD:1624291
RGD:13792537
G Slc25a42 solute carrier family 25, member 42 JBrowse link 16 20,962,144 21,000,191 RGD:1600115
RGD:1624291
carnitine transmembrane transporter activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc22a16 solute carrier family 22 member 16 JBrowse link 20 45,658,398 45,669,192 RGD:1624291
G Slc22a4 solute carrier family 22 member 4 JBrowse link 10 39,334,972 39,373,508 RGD:1624291
G Slc22a5 solute carrier family 22 member 5 JBrowse link 10 39,201,101 39,228,090 RGD:730132
RGD:1624291
RGD:1643150
RGD:1643142
RGD:1643141
RGD:1643135
choline transmembrane transporter activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:628453
G Slc44a1 solute carrier family 44 member 1 JBrowse link 5 70,243,643 70,424,115 RGD:1624291
RGD:1600115
G Slc44a4 solute carrier family 44, member 4 JBrowse link 20 4,593,389 4,609,641 RGD:1624291
RGD:1600115
G Slc5a7 solute carrier family 5 member 7 JBrowse link 9 5,294,377 5,330,822 RGD:68853
RGD:1624291
G Slc6a8 solute carrier family 6 member 8 JBrowse link X 157,129,987 157,139,321 RGD:634748
RGD:13792537
RGD:737698
choline:sodium symporter activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc5a7 solute carrier family 5 member 7 JBrowse link 9 5,294,377 5,330,822 RGD:1624291
RGD:13792537
RGD:1600115
putrescine transmembrane transporter activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Azin2 antizyme inhibitor 2 JBrowse link 5 147,120,128 147,148,576 RGD:1600115
RGD:1624291
G Oaz3 ornithine decarboxylase antizyme 3 JBrowse link 2 195,675,925 195,678,859 RGD:1624291
quaternary ammonium group transmembrane transporter activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc22a1 solute carrier family 22 member 1 JBrowse link 1 48,273,639 48,300,645 RGD:1643122
RGD:1643126
RGD:1643123
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:1643123
G Slc22a3 solute carrier family 22 member 3 JBrowse link 1 48,433,079 48,521,261 RGD:70010
RGD:1624291
G Slc22a4 solute carrier family 22 member 4 JBrowse link 10 39,334,972 39,373,508 RGD:633351
RGD:13792537
RGD:1624291
RGD:1643126
G Slc22a5 solute carrier family 22 member 5 JBrowse link 10 39,201,101 39,228,090 RGD:70011
RGD:13792537
RGD:1624291
RGD:1643141
RGD:1643135
RGD:1643126
G Slc22a8 solute carrier family 22 member 8 JBrowse link 1 224,799,444 224,818,482 RGD:1643126
secondary active organic cation transmembrane transporter activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc22a1 solute carrier family 22 member 1 JBrowse link 1 48,273,639 48,300,645 RGD:634159
thiamine pyrophosphate transmembrane transporter activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc44a4 solute carrier family 44, member 4 JBrowse link 20 4,593,389 4,609,641 RGD:1624291
RGD:1600115

Term paths to the root
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Term Annotations click to browse term
  molecular_function 18263
    transporter activity 1190
      transmembrane transporter activity 1054
        ion transmembrane transporter activity 863
          cation transmembrane transporter activity 635
            organic cation transmembrane transporter activity 22
              AMP transmembrane transporter activity 2
              ATPase-coupled betaine transporter activity 0
              ATPase-coupled daunorubicin transmembrane transporter activity 0
              ATPase-coupled doxorubicin transmembrane transporter activity 0
              acetylcholine transmembrane transporter activity + 2
              acriflavine transmembrane transporter activity 0
              amiloride transmembrane transporter activity + 0
              arginine:agmatine antiporter activity 0
              choline transmembrane transporter activity + 5
              ethanolamine transmembrane transporter activity 0
              lysine:cadaverine antiporter activity 0
              methylammonium transmembrane transporter activity + 0
              putrescine transmembrane transporter activity + 2
              pyridoxal transmembrane transporter activity 0
              pyridoxamine transmembrane transporter activity 0
              quaternary ammonium group transmembrane transporter activity + 12
              secondary active organic cation transmembrane transporter activity 1
              spermidine transmembrane transporter activity + 0
              thiamine pyrophosphate transmembrane transporter activity 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.