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ONTOLOGY REPORT - ANNOTATIONS

Term:ferrous iron transmembrane transporter activity
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Accession:GO:0015093 term browser browse the term
Definition:Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other.
Synonyms:related_synonym: ferrous iron uptake transmembrane transporter activity
 alt_id: GO:0015639
 xref: MetaCyc:TRANS-RXN-8;   RHEA:28486;   Reactome:R-HSA-5655760 "Defective SLC40A1 does not transport Fe3+ from extracellular region to cytosol";   reactome:R-HSA-1362417 "Mitoferrin translocates iron from the mitochondrial intermembrane space to the mitochondrial matrix";   reactome:R-HSA-442368 "SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region"


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ferrous iron transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmgt1 membrane magnesium transporter 1 enables ISO (PMID:18057121) RGD PMID:18057121 NCBI chr  X:134,408,463...134,420,798
Ensembl chr  X:134,408,466...134,420,729 		JBrowse link
G Slc11a2 solute carrier family 11 member 2 enables IMP
ISO
ISS
IEA
IBA		 (PMID:12734107), (PMID:17293870), (PMID:25491917)
GO_REF:0000024
GO_REF:0000107
(PMID:17109629)
GO_REF:0000118
GO_REF:0000033		 RGD
UniProt
Ensembl
TreeGrafter
GO_Central		 PMID:12734107 PMID:17109629 PMID:17293870 PMID:25491917 PMID:16091957 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118, RGD:1580427 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145 		JBrowse link
G Slc25a28 solute carrier family 25 member 28 enables ISO
IBA		 (MGI:3690197|PMID:16511496), (MGI:3835911|PMID:19075006), (MGI:4361776|PMID:19805291)
GO_REF:0000033		 RGD
GO_Central		 PMID:16511496 PMID:19075006 PMID:19805291 GO_REF:0000033 MGI:3690197 MGI:3835911 MGI:4361776 NCBI chr 1:242,530,877...242,542,140
Ensembl chr 1:242,530,899...242,542,115 		JBrowse link
G Slc25a37 solute carrier family 25 member 37 enables ISO
IEA
IBA		 (MGI:3690197|PMID:16511496), (MGI:3835911|PMID:19075006), (MGI:4361776|PMID:19805291)
GO_REF:0000118
GO_REF:0000033		 RGD
TreeGrafter
GO_Central		 PMID:16511496 PMID:19075006 PMID:19805291 GO_REF:0000033 GO_REF:0000118 MGI:3690197 MGI:3835911 MGI:4361776 NCBI chr15:44,534,280...44,576,697
Ensembl chr15:44,536,727...44,577,199 		JBrowse link
G Slc39a14 solute carrier family 39 member 14 enables ISO (PMID:16950869) RGD PMID:16950869 NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524 		JBrowse link
G Slc40a1 solute carrier family 40 member 1 enables ISO (MGI:3521561|PMID:15514116) RGD PMID:15514116 MGI:3521561 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  molecular_function 21010
    transporter activity 1259
      transmembrane transporter activity 1163
        inorganic molecular entity transmembrane transporter activity 695
          inorganic cation transmembrane transporter activity 582
            metal ion transmembrane transporter activity 461
              transition metal ion transmembrane transporter activity 40
                iron ion transmembrane transporter activity 8
                  ferrous iron transmembrane transporter activity 6
                    high-affinity ferrous iron transmembrane transporter activity 0
paths to the root