ONTOLOGY REPORT - ANNOTATIONS
Term: glucuronosyltransferase activity
Accession: GO:0015020
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Definition: Catalysis of the reaction: glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + H+ + UDP.
Synonyms: narrow_synonym: 1-naphthol glucuronyltransferase activity; 1-naphthol-UDP-glucuronosyltransferase activity; 17-OH steroid UDPGT activity; 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity; 17beta-hydroxysteroid UDP-glucuronosyltransferase activity; 3-OH androgenic UDPGT activity; 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity; 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity; 4-hydroxybiphenyl UDP-glucuronosyltransferase activity; 4-methylumbelliferone UDP-glucuronosyltransferase activity; 4-nitrophenol UDP-glucuronyltransferase activity; 4-nitrophenol UDPGT activity; Phenyl-UDP-glucuronosyltransferase activity; UDP glucuronate-estradiol-glucuronosyltransferase activity; UDP glucuronate-estriol glucuronosyltransferase activity; UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity; UDP-glucuronate-bilirubin glucuronyltransferase activity; UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity; bilirubin UDP-glucuronosyltransferase activity; bilirubin UDPGT activity; bilirubin glucuronyltransferase activity; bilirubin monoglucuronide glucuronyltransferase activity; bilirubin uridine diphosphoglucuronyltransferase activity; ciramadol UDP-glucuronyltransferase activity; estriol UDPglucuronosyltransferase activity; estrone UDPglucuronosyltransferase activity; morphine glucuronyltransferase activity; p-hydroxybiphenyl UDP glucuronyltransferase activity; p-nitrophenol UDP-glucuronosyltransferase activity; p-nitrophenol UDP-glucuronyltransferase activity; p-nitrophenylglucuronosyltransferase activity; p-phenylphenol glucuronyltransferase activity; pnp-UDPGT activity; uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity; uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity; uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity; uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity; uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity; uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity; uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity; uridine diphosphoglucuronate-estriol glucuronosyltransferase activity
related_synonym: GT activity; PNP-UDPGT; UDP glucuronic acid transferase activity; UDP glucuronosyltransferase activity; UDP glucuronyltransferase activity; UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific); UDPGA transferase activity; UDPGA-glucuronyltransferase activity; UDPGT activity; uridine 5'-diphosphoglucuronyltransferase activity; uridine diphosphate glucuronyltransferase activity; uridine diphosphoglucuronosyltransferase activity; uridine diphosphoglucuronyltransferase activity
alt_id: GO:0003981
xref: EC:2.4.1.17; MetaCyc:UDP-GLUCURONOSYLTRANSFERASE-RXN; RHEA:21032; Reactome:R-HSA-158546 "UGTs glucuronate APAP to APAP-GlcA"; Reactome:R-HSA-159179 "UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG"; Reactome:R-HSA-159194 "UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG"; Reactome:R-HSA-5604954 "Defective UGT1A4 does not transfer GlcA from UDP-GlcA to BIL"; Reactome:R-HSA-5604975 "Defective UGT1A1 does not transfer GlcA from UDP-GlcA to BIL"; Reactome:R-HSA-5617143 "B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA"; Reactome:R-HSA-9036102 "Defective UGT1A1 does not transfer GlcA from UDP-GlcA to BMG"; Reactome:R-HSA-9036104 "Defective UGT1A4 does not transfer GlcA from UDP-GlcA to BMG"; Reactome:R-HSA-9632038 "UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG"; Reactome:R-HSA-9632039 "UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG"; Reactome:R-HSA-9638097 "B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA"; Reactome:R-HSA-9749977 "UGT1A6 glucuronates ST"; Reactome:R-HSA-9756134 "UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL"; Reactome:R-HSA-9756156 "UGT1A3 lactonizes ATV to ATVL"; Reactome:R-HSA-9756183 "UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL"; Reactome:R-HSA-9758661 "UGT2B7,2B17,1A3 glucuronidates PRED metabolites"; reactome:R-HSA-174916 "Formation of N-glucuronides"; reactome:R-HSA-174931 "UGTs transfer GlcA from UDP-GlcA to O-centre substrates"; reactome:R-HSA-2162099 "abacavir + UDP-glucuronate => abacavir 5'-glucuronide + UDP"; reactome:R-HSA-8941701 "UGT1A10 transfers GlcA from UDP-GlcA to GCTN"
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AC114845.1
enables
IEA
GO_REF:0000003 GO_REF:0000116
UniProt RHEA
GO_REF:0000003 GO_REF:0000116
Ensembl chr14:20,717,581...20,737,286
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B3gat3
beta-1,3-glucuronyltransferase 3
enables
ISO
(PMID:21763480), (PMID:25893793)
RGD
PMID:21763480 PMID:25893793
NCBI chr 1:205,817,374...205,823,928
Ensembl chr 1:205,817,378...205,837,807
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B4gat1
beta-1,4-glucuronyltransferase 1
enables
ISO IBA
(PMID:23359570), (PMID:25279697), (PMID:25279699) GO_REF:0000033
RGD GO_Central
PMID:23359570 PMID:25279697 PMID:25279699
GO_REF:0000033
NCBI chr 1:202,343,268...202,345,490
Ensembl chr 1:202,343,240...202,346,065
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Csgalnact1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
enables
ISO
(PMID:11514575)
RGD
PMID:11514575
NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319
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ENSRNOG00000065137
enables
IEA
GO_REF:0000116 GO_REF:0000003
RHEA UniProt
GO_REF:0000003 GO_REF:0000116
Ensembl chr14:20,944,992...20,958,722
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Ext1
exostosin glycosyltransferase 1
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
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Ext2
exostosin glycosyltransferase 2
enables
ISO
(PMID:12907669) (PMID:10639137)
RGD
PMID:10639137 PMID:12907669
NCBI chr 3:79,665,414...79,798,077
Ensembl chr 3:79,665,415...79,798,059
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Extl1
exostosin-like glycosyltransferase 1
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 5:146,573,911...146,589,115
Ensembl chr 5:146,573,912...146,589,115
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Large1
LARGE xylosyl- and glucuronyltransferase 1
enables
ISO IBA
(PMID:22223806), (PMID:25279697), (PMID:25279699) (PMID:23125099), (PMID:23135544), (PMID:23723439), (PMID:25138275) GO_REF:0000033
RGD GO_Central
PMID:22223806 PMID:23125099 PMID:23135544 PMID:23723439 PMID:25138275 PMID:25279697 PMID:25279699 More...
GO_REF:0000033
NCBI chr19:11,603,129...12,048,930
Ensembl chr19:11,603,129...12,048,930
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Large2
LARGE xylosyl- and glucuronyltransferase 2
enables
ISS IBA ISO
GO_REF:0000024 GO_REF:0000033 (PMID:23125099), (PMID:23135544), (PMID:25138275)
UniProt GO_Central RGD
PMID:23125099 PMID:23135544 PMID:25138275
GO_REF:0000024 GO_REF:0000033
NCBI chr 3:78,334,627...78,347,167
Ensembl chr 3:78,336,056...78,342,184
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Ugt1a1
UDP glucuronosyltransferase family 1 member A1
enables
IDA ISO
(PMID:15231852), (PMID:15472229), (PMID:17179145), (PMID:18052087), (PMID:18719240), (PMID:1898728), (PMID:19830808), (PMID:19996319), (PMID:20056724), (PMID:20308471), (PMID:21422672), (PMID:22579593), (PMID:38211441)
RGD
PMID:1898728 PMID:15231852 PMID:15472229 PMID:17179145 PMID:18052087 PMID:18719240 PMID:19830808 PMID:19996319 PMID:20056724 PMID:20308471 PMID:21422672 PMID:22579593 PMID:38211441 PMID:11829457 More...
RGD:70480
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Ugt1a2
UDP glucuronosyltransferase 1 family, polypeptide A2
enables
IEA ISO
GO_REF:0000003 (PMID:17179145), (PMID:18052087), (PMID:18719240), (PMID:20056724), (PMID:20308471), (PMID:21422672), (PMID:22579593)
UniProt RGD
PMID:17179145 PMID:18052087 PMID:18719240 PMID:20056724 PMID:20308471 PMID:21422672 PMID:22579593 More...
GO_REF:0000003
NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Ugt1a3
UDP glycosyltransferase 1 family, polypeptide A3
enables
ISS IEA
GO_REF:0000024 GO_REF:0000003
UniProt
GO_REF:0000003 GO_REF:0000024
NCBI chr 9:88,780,328...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Ugt1a5
UDP glucuronosyltransferase family 1 member A5
enables
IEA ISO
GO_REF:0000003 (PMID:15231852), (PMID:18177842), (PMID:1898728), (PMID:22579593), (PMID:24641623)
UniProt RGD
PMID:1898728 PMID:15231852 PMID:18177842 PMID:22579593 PMID:24641623
GO_REF:0000003
NCBI chr 9:88,762,250...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Ugt1a6
UDP glucuronosyltransferase family 1 member A6
enables
IDA IEA ISO
GO_REF:0000003 (PMID:15231852), (PMID:21422672), (PMID:22579593)
UniProt RGD
PMID:15231852 PMID:21422672 PMID:22579593 PMID:11854153
GO_REF:0000003, RGD:634454
NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Ugt1a7c
UDP glucuronosyltransferase 1 family, polypeptide A7C
IDA
RGD
PMID:8999837
RGD:634473
NCBI chr 9:88,739,577...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Ugt1a8
UDP glucuronosyltransferase family 1 member A8
TAS IDA
RGD
PMID:11854153 PMID:15502008
RGD:634454 , RGD:2317077
NCBI chr 9:88,727,094...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Ugt1a9
UDP glucuronosyltransferase family 1 member A9
NOT|enables
ISO
UniProtKB:Q9HAW9-1 (PMID:20610558) (PMID:15231852), (PMID:18052087), (PMID:20056724), (PMID:20308471), (PMID:21422672), (PMID:22579593), (PMID:38211441)
RGD
PMID:15231852 PMID:18052087 PMID:20056724 PMID:20308471 PMID:20610558 PMID:21422672 PMID:22579593 PMID:38211441 More...
NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Ugt2a1
UDP glucuronosyltransferase family 2 member A1
enables
TAS ISO IEA IBA
(PMID:10359671), (PMID:19858781), (PMID:23756265) GO_REF:0000003 GO_REF:0000033
RGD UniProt GO_Central
PMID:10359671 PMID:19858781 PMID:23756265 PMID:1900353
GO_REF:0000003 GO_REF:0000033, RGD:69395
NCBI chr14:20,521,018...20,545,934
Ensembl chr14:20,517,951...20,545,531
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Ugt2a3
UDP glucuronosyltransferase family 2 member A3
enables
ISO IBA
(PMID:19858781) GO_REF:0000033
RGD GO_Central
PMID:19858781
GO_REF:0000033
NCBI chr14:20,572,793...20,590,795
Ensembl chr14:20,572,808...20,590,729
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Ugt2b
UDP glycosyltransferase 2 family, polypeptide B
enables
IDA IBA IEA
GO_REF:0000033 GO_REF:0000116 GO_REF:0000003
GO_Central RHEA UniProt RGD
PMID:2429951
GO_REF:0000003 GO_REF:0000033 GO_REF:0000116, RGD:634431
NCBI chr14:20,630,572...20,665,062
Ensembl chr14:20,630,250...20,651,776
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Ugt2b1
UDP glucuronosyltransferase 2 family, polypeptide B1
enables
IMP IDA ISO IBA
(PMID:18719240), (PMID:22579593) GO_REF:0000033
RGD GO_Central
PMID:18719240 PMID:22579593 PMID:3084479 PMID:16006569 PMID:18719240
GO_REF:0000033, RGD:1299519 , RGD:1600442 , RGD:40902964
NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
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Ugt2b10
UDP glucuronosyltransferase 2 family, polypeptide B10
enables
IEA
GO_REF:0000003 GO_REF:0000116
UniProt RHEA
GO_REF:0000003 GO_REF:0000116
NCBI chr14:21,107,996...21,128,648
Ensembl chr14:21,108,006...21,127,828
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Ugt2b15
UDP glucuronosyltransferase family 2 member B15
enables
IDA IEA IBA
GO_REF:0000003 GO_REF:0000116 GO_REF:0000033
UniProt RHEA GO_Central RGD
PMID:3110162
GO_REF:0000003 GO_REF:0000033 GO_REF:0000116, RGD:634452
NCBI chr14:20,768,015...20,783,599
Ensembl chr14:20,768,015...20,783,589
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Ugt2b34l1
UDP glucuronosyltransferase 2 family, polypeptide B34 like 1
enables
ISO IBA
(PMID:11300766) GO_REF:0000033
RGD GO_Central
PMID:11300766
GO_REF:0000033
NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704
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Ugt2b35
UDP glucuronosyltransferase 2 family, polypeptide B35
enables
IEA IBA
GO_REF:0000003 GO_REF:0000033
UniProt GO_Central
GO_REF:0000003 GO_REF:0000033
NCBI chr14:20,853,441...20,891,039
Ensembl chr14:20,853,587...20,891,037
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Ugt2b37
UDP-glucuronosyltransferase 2 family, member 37
enables
IDA IEA IBA
GO_REF:0000003 GO_REF:0000116 GO_REF:0000033
UniProt RHEA GO_Central RGD
PMID:1692835
GO_REF:0000003 GO_REF:0000033 GO_REF:0000116, RGD:70049
NCBI chr14:20,817,285...20,833,917
Ensembl chr14:20,817,285...20,833,917
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Ugt2b7
UDP glucuronosyltransferase family 2 member B7
enables
ISS IEA IBA ISO
GO_REF:0000024 GO_REF:0000003 GO_REF:0000116 GO_REF:0000033 (PMID:15231852), (PMID:17442341), (PMID:18052087), (PMID:18719240), (PMID:20056724), (PMID:21422672), (PMID:22579593), (PMID:38211441)
UniProt RHEA GO_Central RGD
PMID:15231852 PMID:17442341 PMID:18052087 PMID:18719240 PMID:20056724 PMID:21422672 PMID:22579593 PMID:38211441 More...
GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000116
NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
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Ugt3a1
UDP glycosyltransferase family 3 member A1
enables
ISO IBA
(PMID:22621930) GO_REF:0000033
RGD GO_Central
PMID:22621930
GO_REF:0000033
NCBI chr 2:58,327,058...58,350,186
Ensembl chr 2:58,334,603...58,350,186
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B3gat1
beta-1,3-glucuronyltransferase 1
enables
IDA ISO IBA
MGI:3759445 (PMID:12032138) GO_REF:0000033 PMID:19181664
RGD GO_Central
PMID:12032138 PMID:9177175 PMID:19181664
GO_REF:0000033, RGD:70805 , RGD:11535107
NCBI chr 8:25,087,123...25,114,692
Ensembl chr 8:25,087,547...25,113,395
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B3gat2
beta-1,3-glucuronyltransferase 2
enables
IMP IBA IEA IDA
GO_REF:0000033 GO_REF:0000104 PMID:10358066 GO_REF:0000116 GO_REF:0000003
GO_Central UniProt RHEA RGD
PMID:10082676 PMID:10358066
GO_REF:0000003 GO_REF:0000033 GO_REF:0000104 GO_REF:0000116, RGD:632232 , RGD:632231
NCBI chr 9:26,167,174...26,250,153
Ensembl chr 9:26,167,174...26,250,153
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B3gat3
beta-1,3-glucuronyltransferase 3
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:205,817,374...205,823,928
Ensembl chr 1:205,817,378...205,837,807
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Eml3
EMAP like 3
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:205,826,354...205,837,790
Ensembl chr 1:205,817,378...205,837,807
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Chpf
chondroitin polymerizing factor
enables
ISO
(PMID:12761225) MGI:1926173|MGI:2681120 (PMID:17253960), (PMID:22952769)
RGD
PMID:12761225 PMID:17253960 PMID:22952769
NCBI chr 9:76,963,178...76,967,878
Ensembl chr 9:76,963,184...76,967,878
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Chsy1
chondroitin sulfate synthase 1
enables
ISO
(PMID:11514575) MGI:106576 (PMID:22952769)
RGD
PMID:11514575 PMID:22952769
NCBI chr 1:119,689,626...119,750,711
Ensembl chr 1:119,686,350...119,750,601
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Chsy3
chondroitin sulfate synthase 3
enables
ISO
MGI:106576 (PMID:17253960)
RGD
PMID:17253960
NCBI chr18:52,644,356...52,901,257
Ensembl chr18:52,644,461...52,898,098
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Ext1
exostosin glycosyltransferase 1
enables
ISO
(PMID:12907669), (PMID:36593275) MGI:108050 (PMID:10639137)
RGD
PMID:10639137 PMID:12907669 PMID:36593275
NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
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Ext2
exostosin glycosyltransferase 2
contributes_to enables
ISO IBA
(PMID:36593275) GO_REF:0000033 MGI:894663 (PMID:10639137)
RGD GO_Central
PMID:10639137 PMID:36593275
GO_REF:0000033
NCBI chr 3:79,665,414...79,798,077
Ensembl chr 3:79,665,415...79,798,059
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