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ONTOLOGY REPORT - ANNOTATIONS


Term:myotube differentiation involved in skeletal muscle regeneration
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Accession:GO:0014908 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.



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myotube differentiation involved in skeletal muscle regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl9 BCL9, transcription coactivator acts_upstream_of_or_within ISO MGI:1933114 (MGI:4368064|PMID:19699733) RGD PMID:19699733 MGI:4368064 NCBI chr 2:184,760,616...184,846,261
Ensembl chr 2:184,760,618...184,786,435
JBrowse link
G Klf5 Kruppel-like factor 5 acts_upstream_of_or_within ISO MGI:4353154|MGI:4421792 (MGI:5823533|PMID:27743478) RGD PMID:27743478 MGI:5823533 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
JBrowse link
G Myod1 myogenic differentiation 1 acts_upstream_of_or_within ISO (MGI:48687|PMID:1348494) RGD PMID:1348494 MGI:48687 NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554
JBrowse link
G Tmem182 transmembrane protein 182 involved_in ISO (MGI:6810807|PMID:34427057) RGD PMID:34427057 MGI:6810807 NCBI chr 9:43,059,432...43,111,318
Ensembl chr 9:43,059,439...43,111,317
JBrowse link
myoblast fusion involved in skeletal muscle regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 Cd81 molecule involved_in ISS
ISO
GO_REF:0000024
(MGI:6282938|PMID:23575678)
UniProt
RGD
PMID:23575678 GO_REF:0000024 MGI:6282938 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660
JBrowse link
G Cd9 CD9 molecule involved_in ISS
ISO
GO_REF:0000024
(MGI:6282938|PMID:23575678)
UniProt
RGD
PMID:23575678 GO_REF:0000024 MGI:6282938 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
JBrowse link
G Mymk myomaker, myoblast fusion factor acts_upstream_of_or_within ISO MGI:4841439 (MGI:5608518|PMID:25085416) RGD PMID:25085416 MGI:5608518 NCBI chr 3:10,388,361...10,397,364
Ensembl chr 3:10,388,361...10,397,343
JBrowse link
G Mymx myomixer, myoblast fusion factor involved_in ISO (MGI:6153677|PMID:29581287) RGD PMID:29581287 MGI:6153677 NCBI chr 9:15,396,638...15,398,264
Ensembl chr 9:15,397,144...15,398,263
JBrowse link
G Ptgfrn prostaglandin F2 receptor inhibitor involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:6282938|PMID:23575678)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:23575678 GO_REF:0000024 GO_REF:0000107 MGI:6282938 NCBI chr 2:188,469,521...188,544,795
Ensembl chr 2:188,469,521...188,544,795
JBrowse link
myotube cell development involved in skeletal muscle regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tmem182 transmembrane protein 182 involved_in ISO (MGI:6810807|PMID:34427057) RGD PMID:34427057 MGI:6810807 NCBI chr 9:43,059,432...43,111,318
Ensembl chr 9:43,059,439...43,111,317
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19512
    developmental process 6931
      developmental growth 840
        tissue regeneration 99
          skeletal muscle tissue regeneration 54
            myotube differentiation involved in skeletal muscle regeneration 9
              myoblast fusion involved in skeletal muscle regeneration 5
              myotube cell development involved in skeletal muscle regeneration 1
Path 2
Term Annotations click to browse term
  biological_process 19512
    cellular process 18319
      cellular developmental process 4585
        cell differentiation 4489
          muscle cell differentiation 440
            striated muscle cell differentiation 331
              myotube differentiation 139
                myotube differentiation involved in skeletal muscle regeneration 9
                  myoblast fusion involved in skeletal muscle regeneration 5
                  myotube cell development involved in skeletal muscle regeneration 1
paths to the root