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ONTOLOGY REPORT - ANNOTATIONS

Term:myotube differentiation involved in skeletal muscle regeneration
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Accession:GO:0014908 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.


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myotube differentiation involved in skeletal muscle regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL9 BCL9 transcription coactivator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19699733) Ensembl
MGI		 PMID:19699733 GO_REF:0000107 NCBI chr 4:99,970,388...100,058,291
Ensembl chr 4:99,970,394...100,058,164 		JBrowse link
G KLF5 KLF transcription factor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27743478) Ensembl
MGI		 PMID:27743478 GO_REF:0000107 NCBI chr11:45,370,009...45,386,673
Ensembl chr11:45,369,810...45,388,314 		JBrowse link
G MYOD1 myogenic differentiation 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:1348494) Ensembl
MGI		 PMID:1348494 GO_REF:0000107 NCBI chr 2:41,422,522...41,424,236
Ensembl chr 2:41,415,775...41,424,435 		JBrowse link
G TMEM182 transmembrane protein 182 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:51,258,464...51,492,690
Ensembl chr 3:51,400,171...51,496,293 		JBrowse link
myoblast fusion involved in skeletal muscle regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD81 CD81 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:1,625,728...1,641,662
Ensembl chr 2:1,625,736...1,641,663 		JBrowse link
G CD9 CD9 molecule involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:64,420,177...64,459,783
Ensembl chr 5:64,420,182...64,460,304 		JBrowse link
G LOC110261530 uncharacterized LOC110261530 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:39,215,933...39,217,275
Ensembl chr 7:39,216,513...39,216,779 		JBrowse link
G MYMK myomaker, myoblast fusion factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25085416) Ensembl
MGI		 PMID:25085416 GO_REF:0000107 NCBI chr 1:273,101,674...273,111,721
Ensembl chr 1:273,101,678...273,111,727 		JBrowse link
G PTGFRN prostaglandin F2 receptor inhibitor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:103,747,007...103,835,192
Ensembl chr 4:103,745,181...103,793,138 		JBrowse link
myotube cell development involved in skeletal muscle regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TMEM182 transmembrane protein 182 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:51,258,464...51,492,690
Ensembl chr 3:51,400,171...51,496,293 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17799
    developmental process 6719
      developmental growth 851
        tissue regeneration 103
          skeletal muscle tissue regeneration 58
            myotube differentiation involved in skeletal muscle regeneration 9
              myoblast fusion involved in skeletal muscle regeneration 5
              myotube cell development involved in skeletal muscle regeneration 1
Path 2
Term Annotations click to browse term
  biological_process 17799
    cellular process 16838
      cellular developmental process 4523
        cell differentiation 4522
          muscle cell differentiation 475
            striated muscle cell differentiation 354
              myotube differentiation 147
                myotube differentiation involved in skeletal muscle regeneration 9
                  myoblast fusion involved in skeletal muscle regeneration 5
                  myotube cell development involved in skeletal muscle regeneration 1
paths to the root