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ONTOLOGY REPORT - ANNOTATIONS

Term:myotube differentiation involved in skeletal muscle regeneration
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Accession:GO:0014908 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.


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myotube differentiation involved in skeletal muscle regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl9 B cell CLL/lymphoma 9 acts_upstream_of_or_within IGI (PMID:19699733) MGI PMID:19699733 NCBI chr 3:97,110,974...97,205,718
Ensembl chr 3:97,110,978...97,205,233 		JBrowse link
G Klf5 Kruppel-like transcription factor 5 acts_upstream_of_or_within IMP
IDA		 (PMID:27743478) MGI PMID:27743478 NCBI chr14:99,536,127...99,550,848
Ensembl chr14:99,536,127...99,552,472 		JBrowse link
G Myod1 myogenic differentiation 1 acts_upstream_of_or_within IMP (PMID:1348494) MGI PMID:1348494 NCBI chr 7:46,025,898...46,028,516
Ensembl chr 7:46,025,898...46,028,523 		JBrowse link
G Tmem182 transmembrane protein 182 involved_in IMP (MGI:6810807|PMID:34427057) UniProt PMID:34427057 MGI:6810807 NCBI chr 1:40,844,738...40,896,047
Ensembl chr 1:40,844,761...40,896,047 		JBrowse link
myoblast fusion involved in skeletal muscle regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 CD81 antigen involved_in IMP (MGI:6282938|PMID:23575678) UniProt PMID:23575678 MGI:6282938 NCBI chr 7:142,606,487...142,621,667
Ensembl chr 7:142,606,476...142,621,671 		JBrowse link
G Cd9 CD9 antigen involved_in IMP (MGI:6282938|PMID:23575678) UniProt PMID:23575678 MGI:6282938 NCBI chr 6:125,437,229...125,471,723
Ensembl chr 6:125,437,229...125,471,754 		JBrowse link
G Mymk myomaker, myoblast fusion factor acts_upstream_of_or_within IMP (PMID:25085416) MGI PMID:25085416 NCBI chr 2:26,951,648...26,962,173
Ensembl chr 2:26,951,648...26,962,191 		JBrowse link
G Mymx myomixer, myoblast fusion factor involved_in IMP
ISO		 (MGI:6153677|PMID:29581287) UniProt
MGI		 PMID:29581287 GO_REF:0000119 MGI:4834177 MGI:6153677 NCBI chr17:45,911,887...45,913,122
Ensembl chr17:45,911,897...45,913,028 		JBrowse link
G Ptgfrn prostaglandin F2 receptor negative regulator involved_in IMP (MGI:6282938|PMID:23575678) UniProt PMID:23575678 MGI:6282938 NCBI chr 3:100,947,546...101,018,061
Ensembl chr 3:100,947,548...101,017,594 		JBrowse link
G Synb syncytin b acts_upstream_of_or_within IMP (PMID:27589388) MGI PMID:27589388 NCBI chr14:69,527,827...69,549,857
Ensembl chr14:69,526,793...69,531,748 		JBrowse link
myotube cell development involved in skeletal muscle regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tmem182 transmembrane protein 182 involved_in IMP (MGI:6810807|PMID:34427057) UniProt PMID:34427057 MGI:6810807 NCBI chr 1:40,844,738...40,896,047
Ensembl chr 1:40,844,761...40,896,047 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    developmental process 7369
      developmental growth 886
        tissue regeneration 110
          skeletal muscle tissue regeneration 62
            myotube differentiation involved in skeletal muscle regeneration 10
              myoblast fusion involved in skeletal muscle regeneration 6
              myotube cell development involved in skeletal muscle regeneration 1
Path 2
Term Annotations click to browse term
  biological_process 28573
    cellular process 17545
      cellular developmental process 5063
        cell differentiation 5062
          muscle cell differentiation 514
            striated muscle cell differentiation 382
              myotube differentiation 155
                myotube differentiation involved in skeletal muscle regeneration 10
                  myoblast fusion involved in skeletal muscle regeneration 6
                  myotube cell development involved in skeletal muscle regeneration 1
paths to the root