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ONTOLOGY REPORT - ANNOTATIONS

Term:myotube differentiation involved in skeletal muscle regeneration
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Accession:GO:0014908 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.


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myotube differentiation involved in skeletal muscle regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL9 BCL9 transcription coactivator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19699733) Ensembl
MGI		 PMID:19699733 GO_REF:0000107 NCBI chr17:58,105,914...58,189,065
Ensembl chr17:58,168,375...58,189,062 		JBrowse link
G KLF5 KLF transcription factor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27743478) Ensembl
MGI		 PMID:27743478 GO_REF:0000107 NCBI chr22:27,163,179...27,185,241
Ensembl chr22:27,162,397...27,200,871 		JBrowse link
G MYOD1 myogenic differentiation 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:1348494) Ensembl
MGI		 PMID:1348494 GO_REF:0000107 NCBI chr21:40,257,792...40,260,461
Ensembl chr21:40,258,027...40,259,712 		JBrowse link
G TMEM182 transmembrane protein 182 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:40,227,230...40,283,747
Ensembl chr10:40,102,097...40,283,703 		JBrowse link
myoblast fusion involved in skeletal muscle regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD81 CD81 molecule involved_in ISO (PMID:23575678) UniProt PMID:23575678 NCBI chr18:46,466,484...46,474,236
Ensembl chr18:46,466,499...46,473,868 		JBrowse link
G CD9 CD9 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:38,742,539...38,754,984
Ensembl chr27:38,742,963...38,774,576 		JBrowse link
G LOC119881605 syncytin-1-like acts_upstream_of_or_within ISO (PMID:27589388) MGI PMID:27589388
G MYMK myomaker, myoblast fusion factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25085416) Ensembl
MGI		 PMID:25085416 GO_REF:0000107 NCBI chr 9:49,905,580...49,919,849
Ensembl chr 9:49,907,228...49,921,007 		JBrowse link
G MYMX myomixer, myoblast fusion factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:12,626,482...12,630,058 JBrowse link
G PTGFRN prostaglandin F2 receptor inhibitor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:54,337,778...54,378,363
Ensembl chr17:54,296,361...54,379,662 		JBrowse link
myotube cell development involved in skeletal muscle regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TMEM182 transmembrane protein 182 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:40,227,230...40,283,747
Ensembl chr10:40,102,097...40,283,703 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22103
    developmental process 6888
      developmental growth 881
        tissue regeneration 107
          skeletal muscle tissue regeneration 59
            myotube differentiation involved in skeletal muscle regeneration 10
              myoblast fusion involved in skeletal muscle regeneration 6
              myotube cell development involved in skeletal muscle regeneration 1
Path 2
Term Annotations click to browse term
  biological_process 22103
    cellular process 21633
      cellular developmental process 4646
        cell differentiation 4645
          muscle cell differentiation 488
            striated muscle cell differentiation 363
              myotube differentiation 150
                myotube differentiation involved in skeletal muscle regeneration 10
                  myoblast fusion involved in skeletal muscle regeneration 6
                  myotube cell development involved in skeletal muscle regeneration 1
paths to the root