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ONTOLOGY REPORT - ANNOTATIONS

Term:myotube differentiation involved in skeletal muscle regeneration
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Accession:GO:0014908 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.


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myotube differentiation involved in skeletal muscle regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl9 BCL9, transcription coactivator acts_upstream_of_or_within ISO MGI:1933114 (PMID:19699733) RGD PMID:19699733 NCBI chr 2:184,760,616...184,846,261
Ensembl chr 2:184,760,618...184,786,435 		JBrowse link
G Klf5 KLF transcription factor 5 acts_upstream_of_or_within ISO MGI:4353154|MGI:4421792 (PMID:27743478) RGD PMID:27743478 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445 		JBrowse link
G Myod1 myogenic differentiation 1 acts_upstream_of_or_within ISO (PMID:1348494) RGD PMID:1348494 NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554 		JBrowse link
G Tmem182 transmembrane protein 182 involved_in ISO (PMID:34427057) RGD PMID:34427057 NCBI chr 9:43,059,432...43,111,318
Ensembl chr 9:43,059,439...43,111,317 		JBrowse link
myoblast fusion involved in skeletal muscle regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 Cd81 molecule involved_in ISS
ISO		 GO_REF:0000024
(PMID:23575678)		 UniProt
RGD		 PMID:23575678 GO_REF:0000024 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660 		JBrowse link
G Cd9 CD9 molecule involved_in ISS
ISO		 GO_REF:0000024
(PMID:23575678)		 UniProt
RGD		 PMID:23575678 GO_REF:0000024 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222 		JBrowse link
G Mymk myomaker, myoblast fusion factor acts_upstream_of_or_within ISO MGI:4841439 (PMID:25085416) RGD PMID:25085416 NCBI chr 3:10,388,363...10,397,294
Ensembl chr 3:10,388,361...10,397,343 		JBrowse link
G Mymx myomixer, myoblast fusion factor involved_in ISO (PMID:35642635)
(PMID:29581287)		 RGD PMID:29581287 PMID:35642635 NCBI chr 9:15,397,086...15,398,263
Ensembl chr 9:15,397,144...15,398,263 		JBrowse link
G Ptgfrn prostaglandin F2 receptor inhibitor involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23575678)		 UniProt
Ensembl
RGD		 PMID:23575678 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:188,469,521...188,544,795
Ensembl chr 2:188,469,521...188,544,795 		JBrowse link
myotube cell development involved in skeletal muscle regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tmem182 transmembrane protein 182 involved_in ISO (PMID:34427057) RGD PMID:34427057 NCBI chr 9:43,059,432...43,111,318
Ensembl chr 9:43,059,439...43,111,317 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20537
    developmental process 7105
      developmental growth 894
        tissue regeneration 109
          skeletal muscle tissue regeneration 58
            myotube differentiation involved in skeletal muscle regeneration 9
              myoblast fusion involved in skeletal muscle regeneration 5
              myotube cell development involved in skeletal muscle regeneration 1
Path 2
Term Annotations click to browse term
  biological_process 20537
    cellular process 19526
      cellular developmental process 4810
        cell differentiation 4809
          muscle cell differentiation 483
            striated muscle cell differentiation 362
              myotube differentiation 147
                myotube differentiation involved in skeletal muscle regeneration 9
                  myoblast fusion involved in skeletal muscle regeneration 5
                  myotube cell development involved in skeletal muscle regeneration 1
paths to the root