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ONTOLOGY REPORT - ANNOTATIONS


Term:myotube cell development
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Accession:GO:0014904 term browser browse the term
Definition:The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.


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myotube cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmd dystrophin acts_upstream_of_or_within ISO MGI:1856328 (MGI:3849772|PMID:19535499) RGD PMID:19535499 MGI:3849772 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA
(PMID:17531227)
GO_REF:0000107
RGD
Ensembl
PMID:17531227 GO_REF:0000107 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Myod1 myogenic differentiation 1 involved_in ISO (PMID:10672515) RGD PMID:10672515 NCBI chr 1:102,396,538...102,399,248
Ensembl chr 1:102,396,538...102,399,248
JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 acts_upstream_of_or_within ISO (MGI:3821556|PMID:18676376) RGD PMID:18676376 MGI:3821556 NCBI chr 3:165,241,750...165,374,644
Ensembl chr 3:165,245,238...165,360,292
JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 acts_upstream_of_or_within ISO (MGI:3821556|PMID:18676376) RGD PMID:18676376 MGI:3821556 NCBI chr19:38,039,542...38,114,003
Ensembl chr19:38,039,564...38,114,003
JBrowse link
G Smyd3 SET and MYND domain containing 3 acts_upstream_of_or_within ISO (MGI:5500979|PMID:23752591) RGD PMID:23752591 MGI:5500979 NCBI chr13:97,330,120...97,807,813 JBrowse link
neuromuscular junction development, skeletal muscle fiber term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO MGI:1856217 (MGI:5605930|PMID:25014022) RGD PMID:25014022 MGI:5605930 NCBI chr10:49,538,588...49,568,583
Ensembl chr10:49,538,588...49,568,583
JBrowse link
positive regulation of skeletal muscle fiber development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:3778600|PMID:18178581) RGD PMID:18178581 MGI:3778600 NCBI chr 1:220,120,532...220,136,460
Ensembl chr 1:220,120,533...220,136,470
JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857134 (MGI:1928555|PMID:11146504)
Ensembl
RGD
PMID:11146504 GO_REF:0000107 MGI:1928555 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Lmod3 leiomodin 3 involved_in ISO (PMID:25250574) RGD PMID:25250574 NCBI chr 4:129,604,378...129,619,136
Ensembl chr 4:129,604,267...129,619,142
JBrowse link
G Myf5 myogenic factor 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:49,729,533...49,732,974
Ensembl chr 7:49,729,533...49,732,764
JBrowse link
G Myf6 myogenic factor 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:49,739,643...49,741,490
Ensembl chr 7:49,739,646...49,741,540
JBrowse link
G Myod1 myogenic differentiation 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:102,396,538...102,399,248
Ensembl chr 1:102,396,538...102,399,248
JBrowse link
G Myog myogenin involved_in IBA
ISO
ISS
PMID:21873635
(MGI:62381|PMID:8393145)
GO_REF:0000024
RGD
UniProt
PMID:8393145, PMID:21873635 GO_REF:0000024 MGI:62381, RGD:13792537 NCBI chr13:51,126,459...51,129,048
Ensembl chr13:51,126,459...51,129,048
JBrowse link
G Shox2 short stature homeobox 2 involved_in ISO (MGI:4946446|PMID:21156168) RGD PMID:21156168 MGI:4946446 NCBI chr 2:164,118,175...164,126,783
Ensembl chr 2:164,118,191...164,126,783
JBrowse link
regulation of skeletal muscle fiber development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo22 F-box protein 22 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3840749|PMID:19319192)
RGD PMID:19319192, PMID:21873635 MGI:3840749, RGD:13792537 NCBI chr 8:59,770,032...59,786,061
Ensembl chr 8:59,769,994...59,786,065
JBrowse link
G Hdac4 histone deacetylase 4 acts_upstream_of_or_within ISO MGI:1333784|MGI:1931221 (MGI:3763703|PMID:17786239) RGD PMID:17786239 MGI:3763703 NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715
JBrowse link
G Hdac5 histone deacetylase 5 acts_upstream_of_or_within ISO MGI:1931221|MGI:3036234 (MGI:3763703|PMID:17786239) RGD PMID:17786239 MGI:3763703 NCBI chr10:90,140,183...90,169,853
Ensembl chr10:90,140,183...90,151,042
JBrowse link
G Hdac9 histone deacetylase 9 acts_upstream_of_or_within ISO MGI:1333784|MGI:3036284 (MGI:3763703|PMID:17786239) RGD PMID:17786239 MGI:3763703 NCBI chr 6:53,487,367...54,358,694
Ensembl chr 6:53,488,883...54,059,119
JBrowse link
G Naca nascent polypeptide associated complex subunit alpha involved_in ISO (MGI:4867362|PMID:21071677) RGD PMID:21071677 MGI:4867362 NCBI chr 7:2,458,283...2,470,674
Ensembl chr 7:2,458,264...2,470,674
JBrowse link
skeletal muscle fiber development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta1 actin, alpha 1, skeletal muscle involved_in ISS
ISO
GO_REF:0000024
(MGI:78319|PMID:2731651)
UniProt
RGD
PMID:2731651 GO_REF:0000024 MGI:78319 NCBI chr19:56,674,072...56,677,084
Ensembl chr19:56,674,074...56,677,084
JBrowse link
G Actn1 actinin, alpha 1 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 6:103,376,557...103,470,497
Ensembl chr 6:103,375,799...103,470,555
JBrowse link
G Bin3 bridging integrator 3 acts_upstream_of_or_within ISO MGI:3512131 (MGI:5517720|PMID:23872330) RGD PMID:23872330 MGI:5517720 NCBI chr15:51,799,339...51,818,697
Ensembl chr15:51,779,839...51,818,699
JBrowse link
G Cacna1s calcium voltage-gated channel subunit alpha1 S acts_upstream_of_or_within ISO MGI:1856326 (MGI:3630139|PMID:289331), (MGI:53207|PMID:8462749), (MGI:66718|PMID:8143864) RGD PMID:289331 PMID:8143864 PMID:8462749 MGI:3630139 MGI:53207 MGI:66718 NCBI chr13:52,889,570...52,964,558
Ensembl chr13:52,889,737...52,964,155
JBrowse link
G Cav2 caveolin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
ISS
GO_REF:0000107
MGI:2180372 (MGI:3695802|PMID:17200204)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:17200204 GO_REF:0000024 GO_REF:0000107 MGI:3695802 NCBI chr 4:44,573,264...44,580,640
Ensembl chr 4:44,573,264...44,580,638
JBrowse link
G Dner delta/notch-like EGF repeat containing acts_upstream_of_or_within ISO (MGI:3583881|PMID:15965470) RGD PMID:15965470 MGI:3583881 NCBI chr 9:91,965,866...92,291,172
Ensembl chr 9:91,965,866...92,291,220
JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2158814 (MGI:3662804|PMID:16962942)
Ensembl
RGD
PMID:16962942 GO_REF:0000107 MGI:3662804 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Homer1 homer scaffold protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3526529 (MGI:3784629|PMID:18268005)
Ensembl
RGD
PMID:18268005 GO_REF:0000107 MGI:3784629 NCBI chr 2:22,909,550...23,012,303
Ensembl chr 2:22,909,569...23,009,678
JBrowse link
G Kel Kell metallo-endopeptidase (Kell blood group) acts_upstream_of_or_within ISO MGI:103569 (MGI:5550316|PMID:24405768) RGD PMID:24405768 MGI:5550316 NCBI chr 4:70,979,504...70,996,920
Ensembl chr 4:70,979,504...70,996,395
JBrowse link
G Klhl40 kelch-like family member 40 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5700633|PMID:25940086)
MGI:4843038 (MGI:5586592|PMID:24960163)
RGD PMID:24960163 PMID:25940086, PMID:21873635 MGI:5586592 MGI:5700633, RGD:13792537 NCBI chr 8:130,416,265...130,421,871
Ensembl chr 8:130,416,355...130,421,871
JBrowse link
G Klhl41 kelch-like family member 41 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:55,910,177...55,923,303
Ensembl chr 3:55,910,177...55,923,303
JBrowse link
G Lmod3 leiomodin 3 involved_in ISO (MGI:5644091|PMID:25774500), (MGI:5648755|PMID:26035871) RGD PMID:25774500 PMID:26035871 MGI:5644091 MGI:5648755 NCBI chr 4:129,604,378...129,619,136
Ensembl chr 4:129,604,267...129,619,142
JBrowse link
G Myod1 myogenic differentiation 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3840749|PMID:19319192)
Ensembl
RGD
PMID:19319192 GO_REF:0000107 MGI:3840749 NCBI chr 1:102,396,538...102,399,248
Ensembl chr 1:102,396,538...102,399,248
JBrowse link
G Myog myogenin acts_upstream_of_or_within ISO MGI:1857667 (MGI:62381|PMID:8393145) RGD PMID:8393145 MGI:62381 NCBI chr13:51,126,459...51,129,048
Ensembl chr13:51,126,459...51,129,048
JBrowse link
G Myorg myogenesis regulating glycosidase involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:19706595)
(MGI:4422154|PMID:19706595)
PMID:21873635
RGD PMID:19706595, PMID:21873635 MGI:4422154, RGD:13792537 NCBI chr 5:57,873,404...57,882,008
Ensembl chr 5:57,876,498...57,881,944
JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 acts_upstream_of_or_within ISO MGI:2182778 (MGI:1933051|PMID:11254352) RGD PMID:11254352 MGI:1933051 NCBI chr19:38,039,542...38,114,003
Ensembl chr19:38,039,564...38,114,003
JBrowse link
G P2rx2 purinergic receptor P2X 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2687349 (MGI:3766888|PMID:17706883)
Ensembl
RGD
PMID:17706883 GO_REF:0000107 MGI:3766888 NCBI chr12:52,397,666...52,401,005
Ensembl chr12:52,397,792...52,401,015
JBrowse link
G Plec plectin involved_in ISO MGI:3799315 (MGI:3797705|PMID:18490514), (MGI:5567855|PMID:24487589) RGD PMID:18490514 PMID:24487589 MGI:3797705 MGI:5567855 NCBI chr 7:117,230,319...117,291,859
Ensembl chr 7:117,230,319...117,289,961
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha acts_upstream_of_or_within ISO (MGI:3586394|PMID:16024798) RGD PMID:16024798 MGI:3586394 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854
JBrowse link
G Rcan1 regulator of calcineurin 1 acts_upstream_of_or_within ISO (MGI:3586394|PMID:16024798) RGD PMID:16024798 MGI:3586394 NCBI chr11:32,539,689...32,620,274
Ensembl chr11:32,539,683...32,550,539
JBrowse link
G Ripor2 RHO family interacting cell polarization regulator 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:42,324,594...42,549,907
Ensembl chr17:42,324,594...42,422,053
JBrowse link
G Ryr1 ryanodine receptor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3764002|PMID:18003898)
UniProt
RGD
PMID:18003898 GO_REF:0000024 MGI:3764002 NCBI chr 1:87,959,596...88,066,252
Ensembl chr 1:87,959,712...88,066,101
JBrowse link
G Selenon selenoprotein N involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5494499|PMID:23325319)
RGD PMID:23325319, PMID:21873635 MGI:5494499, RGD:13792537 NCBI chr 5:152,748,497...152,765,489
Ensembl chr 5:152,750,284...152,762,165
JBrowse link
G Six1 SIX homeobox 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:95,929,060...95,934,296
Ensembl chr 6:95,929,060...95,934,296
JBrowse link
G Ski SKI proto-oncogene acts_upstream_of_or_within ISO MGI:2177555 (MGI:1095997|PMID:9284043) RGD PMID:9284043 MGI:1095997 NCBI chr 5:172,556,196...172,623,878
Ensembl chr 5:172,559,135...172,623,899
JBrowse link
G Smo smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2176256|MGI:3573783 (MGI:5438143|PMID:22987639)
Ensembl
RGD
PMID:22987639 GO_REF:0000107 MGI:5438143 NCBI chr 4:57,019,941...57,041,779
Ensembl chr 4:57,019,941...57,042,770
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 acts_upstream_of_or_within ISO (MGI:5508972|PMID:23626854) RGD PMID:23626854 MGI:5508972 NCBI chr 7:70,807,427...70,815,271
Ensembl chr 7:70,807,867...70,815,270
JBrowse link
G Wnt10b Wnt family member 10B acts_upstream_of_or_within ISO MGI:3582610 (MGI:3581945|PMID:15673614) RGD PMID:15673614 MGI:3581945 NCBI chr 7:140,448,284...140,466,159
Ensembl chr 7:140,448,465...140,454,268
JBrowse link
G Xk X-linked Kx blood group involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1346053 (MGI:5550316|PMID:24405768)
Ensembl
RGD
PMID:24405768 GO_REF:0000107 MGI:5550316 NCBI chr  X:14,497,376...14,534,479
Ensembl chr  X:14,498,119...14,534,473
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19610
    developmental process 6757
      anatomical structure development 6182
        cell development 2443
          muscle cell development 216
            myotube cell development 44
              myotube cell development involved in skeletal muscle regeneration 0
              skeletal muscle fiber development + 40
Path 2
Term Annotations click to browse term
  biological_process 19610
    developmental process 6757
      cellular developmental process 4463
        cell differentiation 4367
          muscle cell differentiation 429
            striated muscle cell differentiation 324
              myotube differentiation 133
                myotube cell development 44
                  myotube cell development involved in skeletal muscle regeneration 0
                  skeletal muscle fiber development + 40
paths to the root