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ONTOLOGY REPORT - ANNOTATIONS

Term:striated muscle hypertrophy
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Accession:GO:0014897 term browser browse the term
Definition:The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils.

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cardiac muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ang2 angiogenin, ribonuclease A family, member 2 ISO (MGI:5920524|PMID:29065170) RGD PMID:29065170 MGI:5920524 NCBI chr15:28,103,688...28,121,494
Ensembl chr15:28,103,703...28,104,206 		JBrowse link
G Csrp3 cysteine and glycine rich protein 3 involved_in ISO
IEA		 (PMID:12507422)
GO_REF:0000107		 RGD
Ensembl		 PMID:12507422 GO_REF:0000107 NCBI chr 1:104,147,205...104,166,389
Ensembl chr 1:104,147,206...104,166,367 		JBrowse link
G Hdac2 histone deacetylase 2 IEP RGD PMID:19713680 RGD:9590231 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 ISO MGI:2447620 (MGI:4454633|PMID:20382855) RGD PMID:20382855 MGI:4454633 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(MGI:4420536|PMID:19023134)		 Ensembl
UniProt
RGD		 PMID:19023134 GO_REF:0000024 GO_REF:0000107 MGI:4420536 NCBI chr 9:93,112,781...93,130,135
Ensembl chr 9:93,112,805...93,125,014 		JBrowse link
G Lep leptin IDA RGD PMID:20738325 RGD:8693628 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818 		JBrowse link
G Npm1 nucleophosmin 1 IEP RGD PMID:21444791 RGD:11535018 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950 		JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 IEP RGD PMID:22564263 RGD:9835036 NCBI chr11:72,829,407...72,865,815
Ensembl chr11:72,829,238...72,865,902 		JBrowse link
G Ryr2 ryanodine receptor 2 involved_in IEA
ISO		 GO_REF:0000107
MGI:3713774 (MGI:3713015|PMID:17431507)		 Ensembl
RGD		 PMID:17431507 GO_REF:0000107 MGI:3713015 NCBI chr17:65,533,998...65,955,606
Ensembl chr17:65,535,403...65,955,606 		JBrowse link
G Tcap titin-cap involved_in ISO (PMID:15582318) RGD PMID:15582318 NCBI chr10:86,337,705...86,338,414
Ensembl chr10:86,337,728...86,338,411 		JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 IMP RGD PMID:22564263 RGD:9835036 NCBI chr11:29,931,083...30,061,173
Ensembl chr11:29,933,163...30,051,103 		JBrowse link
G Ttn titin involved_in ISO (PMID:11846417) RGD PMID:11846417 NCBI chr 3:63,565,160...63,837,815 JBrowse link
G Zfp418 zinc finger protein 418 ISO MGI:3050453|MGI:6369036|MGI:6369039 (MGI:5920524|PMID:29065170) RGD PMID:29065170 MGI:5920524 NCBI chr 1:69,615,413...69,629,997
Ensembl chr 1:69,615,434...69,629,913 		JBrowse link
cardiac muscle hypertrophy in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO (MGI:5576864|PMID:24137001) RGD PMID:24137001 MGI:5576864 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326 		JBrowse link
G Camta2 calmodulin binding transcription activator 2 involved_in ISO (PMID:16678093) RGD PMID:16678093 NCBI chr10:57,291,192...57,309,638
Ensembl chr10:57,291,192...57,309,298 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO (MGI:5576864|PMID:24137001) RGD PMID:24137001 MGI:5576864 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011 		JBrowse link
G Gata4 GATA binding protein 4 ISO MGI:3054171|MGI:3778685 (MGI:5002493|PMID:20705924) RGD PMID:20705924 MGI:5002493 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965 		JBrowse link
G Gata6 GATA binding protein 6 IEA
ISO		 GO_REF:0000107
MGI:3054171|MGI:3654150 (MGI:5002493|PMID:20705924)		 Ensembl
RGD		 PMID:20705924 GO_REF:0000107 MGI:5002493 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 ISO (MGI:3624193|PMID:16603706) RGD PMID:16603706 MGI:3624193 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531 		JBrowse link
G Inpp5f inositol polyphosphate-5-phosphatase F ISO MGI:4128518 (MGI:4943859|PMID:19875726) RGD PMID:19875726 MGI:4943859 NCBI chr 1:200,037,749...200,116,524
Ensembl chr 1:200,037,749...200,116,524 		JBrowse link
G Kdm4a lysine demethylase 4A ISO (MGI:5050547|PMID:21555854) RGD PMID:21555854 MGI:5050547 NCBI chr 5:136,967,650...137,014,402
Ensembl chr 5:136,967,650...137,014,430 		JBrowse link
G Klf15 Kruppel-like factor 15 ISO (MGI:3709247|PMID:17438289) RGD PMID:17438289 MGI:3709247 NCBI chr 4:122,364,688...122,377,690
Ensembl chr 4:122,365,093...122,377,659 		JBrowse link
G Mef2c myocyte enhancer factor 2C ISO (MGI:1346950|PMID:10531040) RGD PMID:10531040 MGI:1346950 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787 		JBrowse link
G Mir208b microRNA 208b ISO (MGI:5576864|PMID:24137001) RGD PMID:24137001 MGI:5576864 NCBI chr15:33,639,510...33,639,621
Ensembl chr15:33,639,510...33,639,621 		JBrowse link
G Myh6 myosin heavy chain 6 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5576864|PMID:24137001)		 Ensembl
RGD		 PMID:24137001 GO_REF:0000107 MGI:5576864 NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699 		JBrowse link
G Myh7 myosin heavy chain 7 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5576864|PMID:24137001)		 Ensembl
RGD		 PMID:24137001 GO_REF:0000107 MGI:5576864 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089 		JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 ISO MGI:107164 (MGI:2388546|PMID:12370307) RGD PMID:12370307 MGI:2388546 NCBI chr19:38,039,542...38,114,003
Ensembl chr19:38,039,564...38,114,003 		JBrowse link
G Nppa natriuretic peptide A ISO MGI:1857231 (MGI:3606834|PMID:14985074), (MGI:3610438|PMID:15452027), (MGI:5576864|PMID:24137001) RGD PMID:14985074 PMID:15452027 PMID:24137001 MGI:3606834 MGI:3610438 MGI:5576864 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705 		JBrowse link
G Nppb natriuretic peptide B ISO (MGI:5576864|PMID:24137001) RGD PMID:24137001 MGI:5576864 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha ISO MGI:103296 (MGI:2388546|PMID:12370307) RGD PMID:12370307 MGI:2388546 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854 		JBrowse link
G Tcap titin-cap involved_in ISO
IEA		 (PMID:12507422)
GO_REF:0000107		 RGD
Ensembl		 PMID:12507422 GO_REF:0000107 NCBI chr10:86,337,705...86,338,414
Ensembl chr10:86,337,728...86,338,411 		JBrowse link
cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A ISO MGI:104774 (MGI:2664013|PMID:12782680) RGD PMID:12782680 MGI:2664013 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451 		JBrowse link
G Adra1b adrenoceptor alpha 1B ISO MGI:104773 (MGI:2664013|PMID:12782680) RGD PMID:12782680 MGI:2664013 NCBI chr10:29,392,762...29,450,644
Ensembl chr10:29,392,762...29,450,644 		JBrowse link
G Agt angiotensinogen IDA RGD PMID:21376054 RGD:5129173 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 IMP RGD PMID:21173078 RGD:6903878 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842 		JBrowse link
G Akap13 A-kinase anchoring protein 13 IMP RGD PMID:18951085 RGD:2312638 NCBI chr 1:137,089,558...137,315,272
Ensembl chr 1:137,014,272...137,315,272 		JBrowse link
G Ang2 angiogenin, ribonuclease A family, member 2 ISO (MGI:5920524|PMID:29065170) RGD PMID:29065170 MGI:5920524 NCBI chr15:28,103,688...28,121,494
Ensembl chr15:28,103,703...28,104,206 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta IMP RGD PMID:21554860 RGD:6907064 NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039 		JBrowse link
G Gata4 GATA binding protein 4 IDA RGD PMID:20971938 RGD:5131529 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IDA RGD PMID:27854077 RGD:13792737 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 IMP RGD PMID:9769323 RGD:7495831 NCBI chr10:52,196,121...52,301,887
Ensembl chr10:52,196,124...52,290,657 		JBrowse link
G Myl2 myosin light chain 2 IEP RGD PMID:7657802 RGD:1580138 NCBI chr12:39,951,863...39,959,065
Ensembl chr12:39,951,987...39,958,239 		JBrowse link
G Myocd myocardin IMP RGD PMID:18772130 RGD:5132877 NCBI chr10:51,682,053...51,781,458
Ensembl chr10:51,683,540...51,778,986 		JBrowse link
G Nppa natriuretic peptide A IEP RGD PMID:7657802 RGD:1580138 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705 		JBrowse link
G Nppb natriuretic peptide B IEP RGD PMID:7657802 RGD:1580138 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531 		JBrowse link
G Pdlim5 PDZ and LIM domain 5 involved_in IGI PMID:24743145 BHF-UCL PMID:24743145, PMID:24743145 RGD:10054083, RGD:10054083 NCBI chr 2:247,815,214...247,989,198
Ensembl chr 2:247,818,243...247,988,462 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IMP RGD PMID:19542178 RGD:7775063 NCBI chr 1:248,982,039...250,300,952 JBrowse link
G Sorbs2 sorbin and SH3 domain containing 2 involved_in IGI PMID:24743145 BHF-UCL PMID:24743145, PMID:24743145 RGD:10054083, RGD:10054083 NCBI chr16:49,626,205...49,820,223
Ensembl chr16:49,626,205...49,820,235 		JBrowse link
negative regulation of cardiac muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap1 A-kinase anchoring protein 1 IMP RGD PMID:19358331 RGD:2312604 NCBI chr10:76,151,013...76,183,987
Ensembl chr10:76,151,038...76,166,276 		JBrowse link
G Bmp10 bone morphogenetic protein 10 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3695247|PMID:16798733)		 Ensembl
RGD		 PMID:16798733 GO_REF:0000107 MGI:3695247 NCBI chr 4:119,224,906...119,230,534
Ensembl chr 4:119,225,040...119,230,728 		JBrowse link
G Cav3 caveolin 3 involved_in ISO (PMID:12847114)
MGI:2180558 (MGI:3804582|PMID:18552160)		 RGD PMID:12847114 PMID:18552160 MGI:3804582 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917 		JBrowse link
G Fbxo32 F-box protein 32 IMP PMID:24117217 BHF-UCL PMID:24117217 RGD:11079185 NCBI chr 7:98,065,664...98,098,071
Ensembl chr 7:98,063,735...98,098,268 		JBrowse link
G Gata5 GATA binding protein 5 ISO (MGI:5286818|PMID:21633169) RGD PMID:21633169 MGI:5286818 NCBI chr 3:175,701,278...175,709,465
Ensembl chr 3:175,701,280...175,709,465 		JBrowse link
G Glrx3 glutaredoxin 3 ISO (MGI:4461873|PMID:18258855) RGD PMID:18258855 MGI:4461873 NCBI chr 1:209,768,696...209,799,912
Ensembl chr 1:209,768,696...209,799,903 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO (MGI:2157270|PMID:11782539) RGD PMID:11782539 MGI:2157270 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268 		JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 involved_in IGI
IMP		 PMID:24657879 BHF-UCL PMID:24657879, PMID:24657879, PMID:24657879, PMID:24657879 RGD:11344938, RGD:11344938, RGD:11344938, RGD:11344938 NCBI chr17:20,183,440...20,365,219
Ensembl chr17:20,184,245...20,364,714 		JBrowse link
G Mlip muscular LMNA-interacting protein involved_in ISS
ISO		 GO_REF:0000024
(MGI:5581934|PMID:22343712)		 UniProt
RGD		 PMID:22343712 GO_REF:0000024 MGI:5581934 NCBI chr 8:84,409,957...84,634,637
Ensembl chr 8:84,434,784...84,632,817 		JBrowse link
G Notch1 notch receptor 1 ISO (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025 		JBrowse link
G P2rx4 purinergic receptor P2X 4 involved_in ISO (PMID:15130891) RGD PMID:15130891 NCBI chr12:39,308,022...39,325,673
Ensembl chr12:39,308,025...39,325,673 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 ISO (MGI:3836877|PMID:19127022) RGD PMID:19127022 MGI:3836877 NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094 		JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3689643|PMID:16151019)		 Ensembl
RGD		 PMID:16151019 GO_REF:0000107 MGI:3689643 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P25119 (MGI:6158728|PMID:26491108)		 Ensembl
RGD		 PMID:26491108 GO_REF:0000107 MGI:6158728 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO UniProtKB:P25118 (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299 		JBrowse link
G Trim63 tripartite motif containing 63 involved_in IMP PMID:24117217 BHF-UCL PMID:24117217, PMID:24117217 RGD:11079185, RGD:11079185 NCBI chr 5:152,533,362...152,547,138
Ensembl chr 5:152,533,349...152,547,179 		JBrowse link
negative regulation of cardiac muscle hypertrophy in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISO (PMID:19287093)
(MGI:3848765|PMID:19287093)		 RGD PMID:19287093 MGI:3848765 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 IDA RGD PMID:19204184 RGD:9685562 NCBI chr 5:167,951,564...167,966,011
Ensembl chr 5:167,952,728...167,966,009 		JBrowse link
G Foxo1 forkhead box O1 involved_in IMP PMID:26436652 UniProt PMID:26436652, PMID:26436652 RGD:13210548, RGD:13210548 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016 		JBrowse link
G Lmna lamin A/C involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(MGI:5700584|PMID:26436652)		 Ensembl
UniProt
RGD		 PMID:26436652 GO_REF:0000024 GO_REF:0000107 MGI:5700584 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516 		JBrowse link
G Mlip muscular LMNA-interacting protein ISO (MGI:5700584|PMID:26436652), (MGI:5908525|PMID:26359501) RGD PMID:26359501 PMID:26436652 MGI:5700584 MGI:5908525 NCBI chr 8:84,409,957...84,634,637
Ensembl chr 8:84,434,784...84,632,817 		JBrowse link
G Smad3 SMAD family member 3 involved_in IGI PMID:27038547 BHF-UCL PMID:27038547, PMID:27038547 RGD:11535100, RGD:11535100 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349 		JBrowse link
negative regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 IMP RGD PMID:21170593 RGD:6784534 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917 		JBrowse link
G Ctdp1 CTD phosphatase subunit 1 IMP RGD PMID:22569295 RGD:9686371 NCBI chr18:76,922,913...76,985,095
Ensembl chr18:76,922,934...76,984,203 		JBrowse link
G Foxp1 forkhead box P1 IMP RGD PMID:26333362 RGD:11561912 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IMP RGD PMID:24190878 RGD:10449133 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha ISO (MGI:4829580|PMID:20516643) RGD PMID:20516643 MGI:4829580 NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203 		JBrowse link
G Mir451a microRNA 451a IMP RGD PMID:25209900 RGD:11558015 NCBI chr10:65,291,204...65,291,275
Ensembl chr10:65,291,204...65,291,275 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 IMP RGD PMID:22082674 RGD:11533929 NCBI chr 1:162,768,156...162,883,356
Ensembl chr 1:162,768,156...162,883,355 		JBrowse link
G Pi16 peptidase inhibitor 16 ISO (MGI:3810223|PMID:17909105) RGD PMID:17909105 MGI:3810223 NCBI chr20:6,923,176...6,932,786
Ensembl chr20:6,923,489...6,932,786 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha IMP RGD PMID:22198280 RGD:5687133 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 IMP RGD PMID:16380388 RGD:13524577 NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 IDA RGD PMID:9918533 RGD:7207376 NCBI chr13:88,054,817...88,061,108
Ensembl chr13:88,054,817...88,061,108 		JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 IMP RGD PMID:25022898 RGD:13464131 NCBI chr11:45,477,053...45,511,409
Ensembl chr11:45,480,250...45,510,961 		JBrowse link
G Yy1 YY1 transcription factor IMP RGD PMID:18632988 RGD:9588273 NCBI chr 6:132,702,443...132,726,848
Ensembl chr 6:132,702,448...132,727,046 		JBrowse link
G Zfp418 zinc finger protein 418 ISO (MGI:5920524|PMID:29065170) RGD PMID:29065170 MGI:5920524 NCBI chr 1:69,615,413...69,629,997
Ensembl chr 1:69,615,434...69,629,913 		JBrowse link
negative regulation of skeletal muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igfbp5 insulin-like growth factor binding protein 5 ISO (MGI:3039207|PMID:15010534) RGD PMID:15010534 MGI:3039207 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033 		JBrowse link
positive regulation of cardiac muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adk adenosine kinase IMP RGD PMID:21335462 RGD:6482642 NCBI chr15:3,033,535...3,435,888
Ensembl chr15:3,033,495...3,435,888 		JBrowse link
G Adra1a adrenoceptor alpha 1A ISO (MGI:5888970|PMID:27994061) RGD PMID:27994061 MGI:5888970 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451 		JBrowse link
G Agt angiotensinogen IDA PMID:8348686 BHF-UCL PMID:8348686 RGD:8553767 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Becn1 beclin 1 ISO MGI:2683833 (MGI:5888970|PMID:27994061) RGD PMID:27994061 MGI:5888970 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297 		JBrowse link
G Bmp10 bone morphogenetic protein 10 involved_in ISO
IEA
IMP		 (PMID:17921333)
GO_REF:0000107		 RGD
Ensembl		 PMID:17921333, PMID:17921333, PMID:17921333 GO_REF:0000107, RGD:2302083, RGD:2302083 NCBI chr 4:119,224,906...119,230,534
Ensembl chr 4:119,225,040...119,230,728 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta involved_in ISO
ISS		 (PMID:17179159)
GO_REF:0000024		 RGD
UniProt		 PMID:17179159 GO_REF:0000024 NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039 		JBrowse link
G Cdk9 cyclin-dependent kinase 9 IMP RGD PMID:20081228 RGD:9698419 NCBI chr 3:11,742,269...11,747,117
Ensembl chr 3:11,742,266...11,747,113 		JBrowse link
G Ece1 endothelin converting enzyme 1 IMP RGD PMID:20099522 RGD:7243873 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671 		JBrowse link
G Edn1 endothelin 1 involved_in ISO (PMID:12847114) RGD PMID:12847114 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in ISO
IEA		 UniProtKB:P63328|UniProtKB:Q02078 (PMID:24161931)
GO_REF:0000107		 RGD
Ensembl		 PMID:24161931 GO_REF:0000107 NCBI chr16:36,371,489...36,373,551
Ensembl chr16:36,371,489...36,373,546 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO (PMID:19654000), (PMID:19933931) RGD PMID:19654000 PMID:19933931 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609 		JBrowse link
G Mef2a myocyte enhancer factor 2a involved_in ISO
IEA		 UniProtKB:P61296 (PMID:24161931)
GO_REF:0000107		 RGD
Ensembl		 PMID:24161931 GO_REF:0000107 NCBI chr 1:128,207,715...128,341,681
Ensembl chr 1:128,209,971...128,341,263 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in IMP PMID:19654000 UniProt PMID:19654000, PMID:19654000 RGD:5131609, RGD:5131609 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787 		JBrowse link
G Mtpn myotrophin involved_in IMP
ISO		 PMID:18693253
(PMID:10329199)		 RGD PMID:10329199, PMID:18693253, PMID:18693253 RGD:8553542, RGD:8553542 NCBI chr 4:63,012,009...63,039,422
Ensembl chr 4:63,012,011...63,039,422 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in IMP PMID:25625556 UniProt PMID:25625556, PMID:25625556 RGD:10054073, RGD:10054073 NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in IMP PMID:25625556 UniProt PMID:25625556, PMID:25625556 RGD:10054073, RGD:10054073 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
G Pde5a phosphodiesterase 5A involved_in IEA
ISO		 GO_REF:0000107
(MGI:3836877|PMID:19127022)		 Ensembl
RGD		 PMID:19127022 GO_REF:0000107 MGI:3836877 NCBI chr 2:226,899,604...227,044,916
Ensembl chr 2:226,900,619...227,041,576 		JBrowse link
G Pde9a phosphodiesterase 9A involved_in ISS
ISO		 GO_REF:0000024
(MGI:5634842|PMID:25799991)		 UniProt
RGD		 PMID:25799991 GO_REF:0000024 MGI:5634842 NCBI chr20:10,123,624...10,216,325
Ensembl chr20:10,123,651...10,216,548 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha ISO RNAcentral:URS0000021B51_10090|UniProtKB:P61296 (MGI:5562625|PMID:24161931), (MGI:5784969|PMID:24657879) RGD PMID:24161931 PMID:24657879 MGI:5562625 MGI:5784969 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854 		JBrowse link
G Prkca protein kinase C, alpha involved_in IDA PMID:11864993 UniProt PMID:11864993, PMID:11864993 RGD:8554603, RGD:8554603 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947 		JBrowse link
G Ptk2 protein tyrosine kinase 2 ISO (MGI:5888970|PMID:27994061) RGD PMID:27994061 MGI:5888970 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:28679962)		 Ensembl
RGD		 PMID:28679962 GO_REF:0000107 NCBI chr18:1,273,490...1,390,790
Ensembl chr18:1,273,453...1,390,190 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in IMP
ISO		 PMID:28679962
(MGI:6158813|PMID:28679962)		 RGD PMID:28679962, PMID:28679962, PMID:28679962 MGI:6158813, RGD:13601991, RGD:13601991 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 involved_in ISO (PMID:21359875) RGD PMID:21359875 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316 		JBrowse link
G Twf1 twinfilin actin-binding protein 1 ISO (MGI:5882879|PMID:20571053) RGD PMID:20571053 MGI:5882879 NCBI chr 7:135,838,647...135,850,542
Ensembl chr 7:135,838,648...135,850,542 		JBrowse link
positive regulation of cardiac muscle hypertrophy in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp3ca protein phosphatase 3 catalytic subunit alpha ISO (MGI:3848765|PMID:19287093) RGD PMID:19287093 MGI:3848765 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854 		JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 involved_in ISO
IEA		 (PMID:19287093)
GO_REF:0000107		 RGD
Ensembl		 PMID:19287093 GO_REF:0000107 NCBI chr 2:123,329,954...123,467,574
Ensembl chr 2:123,329,875...123,407,496 		JBrowse link
positive regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:18194989 RGD:5129139 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985 		JBrowse link
G Akap6 A-kinase anchoring protein 6 IMP
IDA		 RGD PMID:21550986, PMID:16306226 RGD:6902940, RGD:2312613 NCBI chr 6:73,553,111...73,991,992
Ensembl chr 6:73,553,210...73,990,534 		JBrowse link
G Ccn4 cellular communication network factor 4 IMP RGD PMID:21376054 RGD:5129173 NCBI chr 7:107,695,227...107,723,759
Ensembl chr 7:107,695,215...107,723,772 		JBrowse link
G Ddx39b DExD-box helicase 39B IMP RGD PMID:20116367 RGD:10401141 NCBI chr20:4,806,103...4,818,600
Ensembl chr20:4,806,108...4,818,568 		JBrowse link
G Edn1 endothelin 1 involved_in ISO RNAcentral:URS000006FDD4_9606|RNAcentral:URS000013D17D_9606 (PMID:24117217) RGD PMID:24117217 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G Ep300 E1A binding protein p300 IMP RGD PMID:12724418 RGD:2312280 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296 		JBrowse link
G Fdps farnesyl diphosphate synthase IMP RGD PMID:19716825 RGD:2316294 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219 		JBrowse link
G Hamp hepcidin antimicrobial peptide IMP RGD PMID:24424338 RGD:11041632 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA		 RNAcentral:URS000006FDD4_9606|RNAcentral:URS000013D17D_9606 (PMID:24117217)
GO_REF:0000107		 RGD
Ensembl		 PMID:24117217 GO_REF:0000107 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609 		JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:21318349, PMID:21933187 RGD:10040977, RGD:10040978 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IMP RGD PMID:22989630 RGD:7174736 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647 		JBrowse link
G Parp2 poly (ADP-ribose) polymerase 2 IMP RGD PMID:23261455 RGD:13514044 NCBI chr15:27,739,416...27,749,650
Ensembl chr15:27,739,251...27,749,648 		JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 IMP RGD PMID:23487407 RGD:8693424 NCBI chr 8:21,669,236...21,680,615
Ensembl chr 8:21,669,236...21,680,615 		JBrowse link
G Sirt1 sirtuin 1 IMP RGD PMID:25281201 RGD:13514043 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 IDA RGD PMID:21325829 RGD:9681466 NCBI chr16:49,266,903...49,270,698
Ensembl chr16:49,266,903...49,270,698 		JBrowse link
G Trip10 thyroid hormone receptor interactor 10 IMP RGD PMID:23915320 RGD:11535145 NCBI chr 9:9,689,214...9,702,353
Ensembl chr 9:9,689,475...9,702,306 		JBrowse link
positive regulation of skeletal muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:23470307 RGD:10041029 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967 		JBrowse link
G Mymk myomaker, myoblast fusion factor ISO (MGI:6116777|PMID:28186492) RGD PMID:28186492 MGI:6116777 NCBI chr 3:5,608,243...5,617,689
Ensembl chr 3:5,608,243...5,617,225 		JBrowse link
regulation of cardiac muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lmcd1 LIM and cysteine-rich domains 1 involved_in ISO (PMID:20026769)
(MGI:4442539|PMID:20026769)		 RGD PMID:20026769 MGI:4442539 NCBI chr 4:144,192,989...144,252,554
Ensembl chr 4:144,192,989...144,252,551 		JBrowse link
regulation of cardiac muscle hypertrophy in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp10 bone morphogenetic protein 10 involved_in ISO
IEA		 (PMID:17921333)
GO_REF:0000107		 RGD
Ensembl		 PMID:17921333 GO_REF:0000107 NCBI chr 4:119,224,906...119,230,534
Ensembl chr 4:119,225,040...119,230,728 		JBrowse link
regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col14a1 collagen type XIV alpha 1 chain ISO MGI:3846440 (MGI:5444801|PMID:22906538) RGD PMID:22906538 MGI:5444801 NCBI chr 7:95,054,877...95,274,073
Ensembl chr 7:95,074,236...95,273,298 		JBrowse link
skeletal muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor IMP RGD PMID:7957162 RGD:10043318 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
G Myoc myocilin involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(MGI:5320812|PMID:22371502)		 Ensembl
UniProt
RGD		 PMID:22371502 GO_REF:0000024 GO_REF:0000107 MGI:5320812 NCBI chr13:80,517,531...80,527,928
Ensembl chr13:80,517,536...80,527,928 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20078
    multicellular organismal process 9072
      system process 3458
        muscle system process 461
          muscle hypertrophy 115
            striated muscle hypertrophy 113
              cardiac muscle hypertrophy + 109
              skeletal muscle hypertrophy + 5
paths to the root