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ONTOLOGY REPORT - ANNOTATIONS


Term:muscle atrophy
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Accession:GO:0014889 term browser browse the term
Definition:A process, occurring in the muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.
Comment:GO:0014889 should only be used for annotation when muscle atrophy is a normal physiological process and not a disease process.
Synonyms:xref: Wikipedia:Muscle_atrophy



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muscle atrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo32 F-box protein 32 IDA RGD PMID:11679633 RGD:633893 NCBI chr 7:89,731,626...89,764,761
Ensembl chr 7:89,730,232...89,765,436
JBrowse link
G Gatm glycine amidinotransferase involved_in IEA
ISO
GO_REF:0000107
(PMID:26490222)
Ensembl
RGD
PMID:26490222 GO_REF:0000107 NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IEP RGD PMID:17622304 RGD:4892297 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 IEP RGD PMID:14678786 RGD:9854636 NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512
JBrowse link
G Tbce tubulin folding cofactor E acts_upstream_of_or_within ISO MGI:1856997 (MGI:77306|PMID:7472523) RGD PMID:7472523 MGI:77306 NCBI chr17:51,290,143...51,336,090
Ensembl chr17:51,290,202...51,336,089
JBrowse link
negative regulation of muscle atrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:19260063 RGD:10041027 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Nol3 nucleolar protein 3 involved_in IEA
ISO
GO_REF:0000107
(MGI:5573029|PMID:24312627)
Ensembl
RGD
PMID:24312627 GO_REF:0000107 MGI:5573029 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
positive regulation of muscle atrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ep300 E1A binding protein p300 IMP RGD PMID:22292478 RGD:7349318 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Foxo3 forkhead box O3 involved_in ISO (MGI:3771642|PMID:18054316), (MGI:3771681|PMID:18054315) RGD PMID:18054315 PMID:18054316 MGI:3771642 MGI:3771681 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Myog myogenin involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:5508727|PMID:21465538)
UniProt
Ensembl
RGD
PMID:21465538 GO_REF:0000024 GO_REF:0000107 MGI:5508727 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039
JBrowse link
skeletal muscle atrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:5554485|PMID:24234654) RGD PMID:24234654 MGI:5554485 NCBI chr 1:202,159,081...202,175,012
Ensembl chr 1:202,159,082...202,175,012
JBrowse link
G Asb2 ankyrin repeat and SOCS box-containing 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:6716965|PMID:27182554)
UniProt
RGD
PMID:27182554 GO_REF:0000024 MGI:6716965 NCBI chr 6:122,474,754...122,511,014
Ensembl chr 6:122,474,756...122,510,854
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in ISO (MGI:5707584|PMID:21364645) RGD PMID:21364645 MGI:5707584 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Il15 interleukin 15 IEP RGD PMID:17135303 RGD:1626613 NCBI chr19:25,640,013...25,706,818
Ensembl chr19:25,640,251...25,706,820
JBrowse link
G Ireb2 iron responsive element binding protein 2 IEP RGD PMID:23994517 RGD:12904021 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
JBrowse link
G Mstn myostatin IEP RGD PMID:15758361 RGD:2303594 NCBI chr 9:48,453,982...48,458,809
Ensembl chr 9:48,452,533...48,458,933
JBrowse link
G Myod1 myogenic differentiation 1 IEP RGD PMID:12839833 RGD:1302305 NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554
JBrowse link
G Myog myogenin IEP RGD PMID:12839833 RGD:1302305 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IEP RGD PMID:16870628 RGD:10053649 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 IEP RGD PMID:17885021 RGD:1642984 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Trim63 tripartite motif containing 63 IEP RGD PMID:11679633 RGD:633893 NCBI chr 5:146,533,492...146,547,332
Ensembl chr 5:146,533,507...146,547,322
JBrowse link
striated muscle atrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsn gelsolin involved_in ISO (PMID:19549824) RGD PMID:19549824 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Myog myogenin involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:5508727|PMID:21465538)
UniProt
Ensembl
RGD
PMID:21465538 GO_REF:0000024 GO_REF:0000107 MGI:5508727 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19876
    response to stimulus 10557
      muscle adaptation 148
        muscle atrophy 21
          negative regulation of muscle atrophy 2
          positive regulation of muscle atrophy 3
          regulation of muscle atrophy + 5
          smooth muscle atrophy 0
          striated muscle atrophy + 12
Path 2
Term Annotations click to browse term
  biological_process 19876
    multicellular organismal process 9238
      system process 3555
        muscle system process 475
          muscle adaptation 148
            muscle atrophy 21
              negative regulation of muscle atrophy 2
              positive regulation of muscle atrophy 3
              regulation of muscle atrophy + 5
              smooth muscle atrophy 0
              striated muscle atrophy + 12
paths to the root