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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
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Accession:GO:0014809 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.


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regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casq1 calsequestrin 1 ISO (MGI:MGI:5306707|PMID:22049211)
(MGI:MGI:3814667|PMID:17627988)
UniProtKB
MGI
PMID:17627988, PMID:22049211 MGI:MGI:3814667, MGI:MGI:5306707 NCBI chrNW_004936740:430,367...442,468 JBrowse link
G Dmd dystrophin ISO (MGI:MGI:3837615|PMID:19198614) BHF-UCL PMID:19198614 MGI:MGI:3837615 NCBI chrNW_004936553:7,157,526...7,943,703 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12001
    biological regulation 8793
      regulation of biological quality 3394
        regulation of calcium ion transport into cytosol 107
          regulation of release of sequestered calcium ion into cytosol 80
            regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 24
              regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 2
                negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
                positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
Path 2
Term Annotations click to browse term
  biological_process 12001
    biological regulation 8793
      regulation of biological quality 3394
        homeostatic process 1727
          chemical homeostasis 1063
            ion homeostasis 692
              cellular ion homeostasis 548
                cellular cation homeostasis 536
                  cellular metal ion homeostasis 488
                    cellular calcium ion homeostasis 399
                      regulation of cytosolic calcium ion concentration 307
                        positive regulation of cytosolic calcium ion concentration 270
                          calcium ion transport into cytosol 156
                            calcium ion transmembrane import into cytosol 133
                              release of sequestered calcium ion into cytosol 108
                                release of sequestered calcium ion into cytosol by endoplasmic reticulum 26
                                  release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 25
                                    regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 24
                                      regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 2
                                        negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
                                        positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
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