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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
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Accession:GO:0014809 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.



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regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casq1 calsequestrin 1 involved_in
acts_upstream_of_or_within
ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
MGI:3530841 (MGI:3814667|PMID:17627988)
(MGI:5306707|PMID:22049211)
UniProt
RGD
PMID:17627988 PMID:22049211 PMID:21873635 GO_REF:0000024 MGI:3814667 MGI:5306707, RGD:13792537 NCBI chr13:84,670,648...84,680,339
Ensembl chr13:84,670,649...84,680,339
JBrowse link
G Dmd dystrophin involved_in ISO (MGI:3837615|PMID:19198614) RGD PMID:19198614 MGI:3837615 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19512
    biological regulation 13616
      regulation of biological quality 4216
        regulation of calcium ion transport into cytosol 118
          regulation of release of sequestered calcium ion into cytosol 89
            regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 28
              regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 2
                negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
                positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
Path 2
Term Annotations click to browse term
  biological_process 19512
    biological regulation 13616
      regulation of biological quality 4216
        homeostatic process 2024
          chemical homeostasis 1377
            ion homeostasis 881
              cellular ion homeostasis 745
                cellular cation homeostasis 729
                  cellular metal ion homeostasis 660
                    cellular calcium ion homeostasis 521
                      regulation of cytosolic calcium ion concentration 419
                        positive regulation of cytosolic calcium ion concentration 367
                          calcium ion transport into cytosol 182
                            calcium ion transmembrane import into cytosol 158
                              release of sequestered calcium ion into cytosol 132
                                release of sequestered calcium ion into cytosol by endoplasmic reticulum 32
                                  release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 31
                                    regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 28
                                      regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 2
                                        negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
                                        positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
paths to the root