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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
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Accession:GO:0014809 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.


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regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASQ1 calsequestrin 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:90,276,752...90,288,990
Ensembl chr 4:90,276,754...90,288,011
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G DMD dystrophin IEA Ensembl GO_REF:0000107 NCBI chr  X:27,028,223...29,650,728
Ensembl chr  X:27,028,223...29,181,689
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16545
    biological regulation 12011
      regulation of biological quality 3985
        regulation of calcium ion transport into cytosol 111
          regulation of release of sequestered calcium ion into cytosol 83
            regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 23
              regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 2
                negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
                positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
Path 2
Term Annotations click to browse term
  biological_process 16545
    biological regulation 12011
      regulation of biological quality 3985
        homeostatic process 1962
          chemical homeostasis 1249
            ion homeostasis 828
              cellular ion homeostasis 672
                cellular cation homeostasis 659
                  cellular metal ion homeostasis 592
                    cellular calcium ion homeostasis 481
                      regulation of cytosolic calcium ion concentration 380
                        positive regulation of cytosolic calcium ion concentration 335
                          calcium ion transport into cytosol 172
                            calcium ion transmembrane import into cytosol 149
                              release of sequestered calcium ion into cytosol 121
                                release of sequestered calcium ion into cytosol by endoplasmic reticulum 28
                                  release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 27
                                    regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 23
                                      regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 2
                                        negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
                                        positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.