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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
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Accession:GO:0014809 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.


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regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASQ1 calsequestrin 1 ISS
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000024 NCBI chr 1:160,190,575...160,201,886
Ensembl chr 1:160,190,575...160,201,886
JBrowse link
G DMD dystrophin IEA
ISS
(PMID:19198614) Ensembl
BHF-UCL
PMID:19198614 GO_REF:0000107 NCBI chr  X:31,119,219...33,339,460
Ensembl chr  X:31,097,677...33,339,441
JBrowse link
G GSTM2 glutathione S-transferase mu 2 IC (PMID:17023043) BHF-UCL PMID:17023043 NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551
JBrowse link
positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSTO1 glutathione S-transferase omega 1 IC (PMID:11035031) BHF-UCL PMID:11035031 NCBI chr10:104,254,173...104,267,455
Ensembl chr10:104,235,356...104,267,459
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18670
    biological regulation 13306
      regulation of biological quality 4602
        regulation of calcium ion transport into cytosol 127
          regulation of release of sequestered calcium ion into cytosol 96
            regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 30
              regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 4
                negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
                positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 1
Path 2
Term Annotations click to browse term
  biological_process 18670
    biological regulation 13306
      regulation of biological quality 4602
        homeostatic process 2206
          chemical homeostasis 1390
            ion homeostasis 930
              cellular ion homeostasis 767
                cellular cation homeostasis 754
                  cellular metal ion homeostasis 671
                    cellular calcium ion homeostasis 527
                      regulation of cytosolic calcium ion concentration 414
                        positive regulation of cytosolic calcium ion concentration 371
                          calcium ion transport into cytosol 190
                            calcium ion transmembrane import into cytosol 165
                              release of sequestered calcium ion into cytosol 136
                                release of sequestered calcium ion into cytosol by endoplasmic reticulum 34
                                  release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 33
                                    regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 30
                                      regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 4
                                        negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
                                        positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.