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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
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Accession:GO:0014809 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.


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regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASQ1 calsequestrin 1 ISO (MGI:MGI:5306707|PMID:22049211)
(MGI:MGI:3814667|PMID:17627988)
UniProtKB
MGI
PMID:17627988, PMID:22049211 MGI:MGI:3814667, MGI:MGI:5306707 NCBI chr 1:135,544,249...135,555,545
Ensembl chr 1:139,465,605...139,476,969
JBrowse link
G DMD dystrophin ISO (MGI:MGI:3837615|PMID:19198614) BHF-UCL PMID:19198614 MGI:MGI:3837615 NCBI chr  X:23,728,650...26,338,849
Ensembl chr  X:31,282,415...33,492,733
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12555
    biological regulation 9151
      regulation of biological quality 3489
        regulation of calcium ion transport into cytosol 116
          regulation of release of sequestered calcium ion into cytosol 87
            regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 25
              regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 2
                negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
                positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
Path 2
Term Annotations click to browse term
  biological_process 12555
    biological regulation 9151
      regulation of biological quality 3489
        homeostatic process 1791
          chemical homeostasis 1102
            ion homeostasis 721
              cellular ion homeostasis 573
                cellular cation homeostasis 561
                  cellular metal ion homeostasis 512
                    cellular calcium ion homeostasis 421
                      regulation of cytosolic calcium ion concentration 326
                        positive regulation of cytosolic calcium ion concentration 289
                          calcium ion transport into cytosol 165
                            calcium ion transmembrane import into cytosol 140
                              release of sequestered calcium ion into cytosol 116
                                release of sequestered calcium ion into cytosol by endoplasmic reticulum 28
                                  release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 27
                                    regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 25
                                      regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 2
                                        negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
                                        positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
paths to the root

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