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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
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Accession:GO:0014809 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.


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regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casq1 calsequestrin 1 ISS
ISO
IBA
GO_REF:0000024
MGI:MGI:3530841 (MGI:MGI:3814667|PMID:17627988), (MGI:MGI:5306707|PMID:22049211)
PMID:21873635
UniProt
RGD
PMID:17627988, PMID:22049211, PMID:21873635 GO_REF:0000024, MGI:MGI:3814667, MGI:MGI:5306707, RGD:13792537 NCBI chr13:90,592,676...90,602,365
Ensembl chr13:90,592,681...90,602,365
JBrowse link
G Dmd dystrophin ISO (MGI:MGI:3837615|PMID:19198614) RGD PMID:19198614 MGI:MGI:3837615 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    biological regulation 13773
      regulation of biological quality 4280
        regulation of calcium ion transport into cytosol 117
          regulation of release of sequestered calcium ion into cytosol 88
            regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 28
              regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 2
                negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
                positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
Path 2
Term Annotations click to browse term
  biological_process 20027
    biological regulation 13773
      regulation of biological quality 4280
        homeostatic process 2077
          chemical homeostasis 1334
            ion homeostasis 887
              cellular ion homeostasis 730
                cellular cation homeostasis 717
                  cellular metal ion homeostasis 649
                    cellular calcium ion homeostasis 515
                      regulation of cytosolic calcium ion concentration 412
                        positive regulation of cytosolic calcium ion concentration 361
                          calcium ion transport into cytosol 176
                            calcium ion transmembrane import into cytosol 152
                              release of sequestered calcium ion into cytosol 127
                                release of sequestered calcium ion into cytosol by endoplasmic reticulum 32
                                  release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 31
                                    regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 28
                                      regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 2
                                        negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
                                        positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.