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ONTOLOGY REPORT - ANNOTATIONS


Term:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
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Accession:GO:0014808 term browser browse the term
Definition:The process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.


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release of sequestered calcium ion into cytosol by sarcoplasmic reticulum term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nol3 nucleolar protein 3 ISO (PMID:15509781) UniProtKB PMID:15509781 NCBI chrNW_004936475:17,644,299...17,648,213 JBrowse link
G Ryr1 ryanodine receptor 1 ISO PMID:11316255
(MGI:3764002|PMID:18003898)
UniProt PMID:11316255, PMID:18003898 MGI:3764002, RGD:12903237 NCBI chrNW_004936801:1,185,615...1,298,416 JBrowse link
G Ryr2 ryanodine receptor 2 ISO (PMID:12919952)
(MGI:2182484|PMID:12089338)
(MGI:4442115|PMID:20226167)
(PMID:15041652)
BHF-UCL
MGI
PMID:12089338, PMID:12919952, PMID:15041652, PMID:20226167 MGI:2182484, MGI:4442115 NCBI chrNW_004936484:15,402,488...15,825,410 JBrowse link
G Tmem38a transmembrane protein 38A ISO (MGI:3715564|PMID:17611541) MGI PMID:17611541 MGI:3715564 NCBI chrNW_004936596:3,965,220...3,984,120 JBrowse link
G Tmem38b transmembrane protein 38B ISO (MGI:3715564|PMID:17611541) MGI PMID:17611541 MGI:3715564 NCBI chrNW_004936559:6,501,890...6,553,446 JBrowse link
G Trdn triadin ISO (MGI:3849347|PMID:19383796) MGI PMID:19383796 MGI:3849347 NCBI chrNW_004936802:389,653...637,372 JBrowse link
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 ISO (PMID:17178715)
(MGI:5427070|PMID:21859974), (MGI:5430893|PMID:17178715)
BHF-UCL PMID:17178715, PMID:21859974 MGI:5427070, MGI:5430893 NCBI chrNW_004936563:3,520,195...4,170,716 JBrowse link
G Asph aspartate beta-hydroxylase ISO (PMID:17400717) BHF-UCL PMID:17400717 NCBI chrNW_004936496:11,604,992...11,815,680 JBrowse link
G Casq2 calsequestrin 2 ISO (PMID:16601229), (PMID:16908766)
(MGI:3689635|PMID:16932808)
(MGI:1202079|PMID:9525981)
PMID:17569730
BHF-UCL
UniProt
MGI
PMID:9525981, PMID:16601229, PMID:16908766, PMID:16932808, PMID:17569730 MGI:1202079, MGI:3689635, RGD:2314601 NCBI chrNW_004936627:1,001,681...1,069,377 JBrowse link
G Dmd dystrophin ISO (MGI:4420848|PMID:20080623) BHF-UCL PMID:20080623 MGI:4420848 NCBI chrNW_004936553:7,157,526...7,943,703 JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B ISO (MGI:3621834|PMID:12837242) BHF-UCL PMID:12837242 MGI:3621834 NCBI chrNW_004936493:7,916,002...7,922,747 JBrowse link
G Pln phospholamban ISO (MGI:82999|PMID:8831698) MGI PMID:8831698 MGI:82999 NCBI chrNW_004936658:1,443,626...1,453,770 JBrowse link
G Ryr2 ryanodine receptor 2 ISO (MGI:3621834|PMID:12837242) BHF-UCL PMID:12837242 MGI:3621834 NCBI chrNW_004936484:15,402,488...15,825,410 JBrowse link
G Slc8a1 solute carrier family 8 member A1 ISO PMID:21779914 BHF-UCL PMID:21779914 RGD:8554732 NCBI chrNW_004936508:10,894,918...11,256,084 JBrowse link
G Tmem38a transmembrane protein 38A ISO (MGI:3715564|PMID:17611541) MGI PMID:17611541 MGI:3715564 NCBI chrNW_004936596:3,965,220...3,984,120 JBrowse link
G Tmem38b transmembrane protein 38B ISO (MGI:3715564|PMID:17611541) MGI PMID:17611541 MGI:3715564 NCBI chrNW_004936559:6,501,890...6,553,446 JBrowse link
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm2 calmodulin 2 ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chrNW_004936508:5,207,909...5,223,780 JBrowse link
G Calm3 calmodulin 3 ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chrNW_004936664:471,446...480,858 JBrowse link
G Camk2d calcium/calmodulin dependent protein kinase II delta ISO PMID:12676813 BHF-UCL PMID:12676813 RGD:10047271 NCBI chrNW_004936563:4,226,412...4,526,139 JBrowse link
G Casq1 calsequestrin 1 ISO (MGI:3814667|PMID:17627988)
(MGI:2449410|PMID:12419813)
MGI PMID:12419813, PMID:17627988 MGI:2449410, MGI:3814667 NCBI chrNW_004936740:430,367...442,468 JBrowse link
G Casq2 calsequestrin 2 ISO (PMID:15041652)
(MGI:3689635|PMID:16932808)
BHF-UCL
UniProt
PMID:15041652, PMID:16932808 MGI:3689635 NCBI chrNW_004936627:1,001,681...1,069,377 JBrowse link
G Chd7 chromodomain helicase DNA binding protein 7 ISO (MGI:5694290|PMID:26102480) MGI PMID:26102480 MGI:5694290 NCBI chrNW_004936496:12,381,225...12,505,121 JBrowse link
G Clic2 chloride intracellular channel 2 ISO (PMID:15147738), (PMID:15916532) BHF-UCL PMID:15147738, PMID:15916532 NCBI chrNW_004936927:514,989...543,691 JBrowse link
G Dhrs7c dehydrogenase/reductase 7C ISO (MGI:5306721|PMID:21995425) MGI PMID:21995425 MGI:5306721 NCBI chrNW_004936595:2,732,106...2,769,782 JBrowse link
G Dmd dystrophin ISO (MGI:4420848|PMID:20080623), (MGI:5487906|PMID:23263329) BHF-UCL PMID:20080623, PMID:23263329 MGI:4420848, MGI:5487906 NCBI chrNW_004936553:7,157,526...7,943,703 JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B ISO (PMID:20431056)
(MGI:3028710|PMID:14592808), (MGI:5007884|PMID:19578067)
(MGI:3639647|PMID:16672364)
BHF-UCL
MGI
PMID:14592808, PMID:16672364, PMID:19578067, PMID:20431056 MGI:3028710, MGI:3639647, MGI:5007884 NCBI chrNW_004936493:7,916,002...7,922,747 JBrowse link
G Gsto1 glutathione S-transferase omega 1 ISO (PMID:11035031) BHF-UCL PMID:11035031 NCBI chrNW_004936600:1,932,152...1,943,342 JBrowse link
G Hrc histidine rich calcium binding protein ISO (PMID:24125847) BHF-UCL PMID:24125847 NCBI chrNW_004936664:3,088,072...3,092,034 JBrowse link
G LOC101967074 calmodulin ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chrNW_004936488:17,580,425...17,588,480 JBrowse link
G Mettl21c methyltransferase like 21C ISO (MGI:5781029|PMID:24677265) MGI PMID:24677265 MGI:5781029 NCBI chrNW_004936472:8,355,075...8,366,229 JBrowse link
G Nol3 nucleolar protein 3 ISO PMID:23382383 UniProt PMID:23382383 RGD:10047354 NCBI chrNW_004936475:17,644,299...17,648,213 JBrowse link
G Pde4d phosphodiesterase 4D ISO (MGI:3690823|PMID:16213210) BHF-UCL PMID:16213210 MGI:3690823 NCBI chrNW_004936480:8,123,437...9,235,586 JBrowse link
G Pln phospholamban ISO (MGI:3655341|PMID:9118481) MGI PMID:9118481 MGI:3655341 NCBI chrNW_004936658:1,443,626...1,453,770 JBrowse link
G Trdn triadin ISO (PMID:15041652) BHF-UCL
RGD
PMID:15041652, PMID:17569730 RGD:2314601 NCBI chrNW_004936802:389,653...637,372 JBrowse link
regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casq1 calsequestrin 1 ISO (MGI:3814667|PMID:17627988)
(MGI:5306707|PMID:22049211)
MGI
UniProt
PMID:17627988, PMID:22049211 MGI:3814667, MGI:5306707 NCBI chrNW_004936740:430,367...442,468 JBrowse link
G Dmd dystrophin ISO (MGI:3837615|PMID:19198614) BHF-UCL PMID:19198614 MGI:3837615 NCBI chrNW_004936553:7,157,526...7,943,703 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12003
    cellular process 11179
      negative regulation of cellular process 4249
        negative regulation of sequestering of calcium ion 108
          release of sequestered calcium ion into cytosol 108
            release of sequestered calcium ion into cytosol by endoplasmic reticulum 26
              release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 25
                regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum + 24
Path 2
Term Annotations click to browse term
  biological_process 12003
    biological regulation 8797
      regulation of biological quality 3387
        homeostatic process 1727
          cellular homeostasis 803
            cellular chemical homeostasis 739
              cellular ion homeostasis 549
                cellular cation homeostasis 537
                  cellular divalent inorganic cation homeostasis 419
                    cellular calcium ion homeostasis 398
                      regulation of cytosolic calcium ion concentration 306
                        positive regulation of cytosolic calcium ion concentration 269
                          calcium ion transport into cytosol 156
                            calcium ion transmembrane import into cytosol 133
                              release of sequestered calcium ion into cytosol 108
                                release of sequestered calcium ion into cytosol by endoplasmic reticulum 26
                                  release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 25
                                    regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum + 24
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.