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ONTOLOGY REPORT - ANNOTATIONS


Term:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
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Accession:GO:0014808 term browser browse the term
Definition:The process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.


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release of sequestered calcium ion into cytosol by sarcoplasmic reticulum term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL3L1 chemokine (C-C motif) ligand 3-like 1 ISS UniProt GO_REF:0000024 NCBI chr12:39,491,999...39,493,345
Ensembl chr12:39,491,885...39,493,370
JBrowse link
G CCR5 chemokine (C-C motif) receptor 5 IEA Ensembl GO_REF:0000107 NCBI chr13:29,382,383...29,387,902
Ensembl chr13:29,383,303...29,387,902
JBrowse link
G LOC100523672 heat shock factor protein 4 IEA Ensembl GO_REF:0000107 NCBI chr 6:27,808,658...27,818,256
Ensembl chr 6:27,808,652...27,813,404
Ensembl chr 6:27,808,652...27,813,404
JBrowse link
G RYR1 ryanodine receptor 1 ISS UniProt GO_REF:0000024 NCBI chr 6:47,339,759...47,458,457 JBrowse link
G RYR2 ryanodine receptor 2 IEA Ensembl GO_REF:0000107 NCBI chr14:53,652,140...54,406,691
Ensembl chr14:53,652,245...54,406,355
JBrowse link
G TMEM38A transmembrane protein 38A IEA Ensembl GO_REF:0000107 NCBI chr 2:60,929,043...60,960,527
Ensembl chr 2:60,929,049...60,960,467
JBrowse link
G TMEM38B transmembrane protein 38B IEA Ensembl GO_REF:0000107 NCBI chr 1:246,973,447...247,024,019
Ensembl chr 1:246,973,436...247,027,527
JBrowse link
G TRDN triadin IEA Ensembl GO_REF:0000107 NCBI chr 1:39,180,544...39,567,245
Ensembl chr 1:39,180,879...39,567,240
JBrowse link
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 ISO (PMID:17178715)
(MGI:5427070|PMID:21859974), (MGI:5430893|PMID:17178715)
BHF-UCL PMID:17178715, PMID:21859974 MGI:5427070, MGI:5430893 NCBI chr 8:109,306,793...109,661,970 JBrowse link
G ASPH aspartate beta-hydroxylase ISO (PMID:17400717) BHF-UCL PMID:17400717 NCBI chr 4:71,902,891...72,107,047
Ensembl chr 4:71,903,359...72,107,046
JBrowse link
G CASQ2 calsequestrin 2 IEA
IBA
(PMID:21873635) Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 4:104,918,204...104,984,019
Ensembl chr 4:104,918,501...104,999,787
JBrowse link
G DMD dystrophin IEA Ensembl GO_REF:0000107 NCBI chr  X:27,028,223...29,650,728
Ensembl chr  X:27,028,223...29,181,689
JBrowse link
G FKBP1B FKBP prolyl isomerase 1B ISO (MGI:3621834|PMID:12837242) BHF-UCL PMID:12837242 MGI:3621834 NCBI chr 3:114,623,529...114,636,200
Ensembl chr 3:114,623,529...114,634,628
JBrowse link
G PLN phospholamban ISO (MGI:82999|PMID:8831698) MGI PMID:8831698 MGI:82999 NCBI chr 1:43,449,354...43,458,925 JBrowse link
G RYR2 ryanodine receptor 2 IEA Ensembl GO_REF:0000107 NCBI chr14:53,652,140...54,406,691
Ensembl chr14:53,652,245...54,406,355
JBrowse link
G SLC8A1 solute carrier family 8 member A1 ISO PMID:21779914 BHF-UCL PMID:21779914 RGD:8554732 NCBI chr 3:99,823,503...100,257,306
Ensembl chr 3:99,897,162...100,245,140
JBrowse link
G TMEM38A transmembrane protein 38A IEA Ensembl GO_REF:0000107 NCBI chr 2:60,929,043...60,960,527
Ensembl chr 2:60,929,049...60,960,467
JBrowse link
G TMEM38B transmembrane protein 38B IEA Ensembl GO_REF:0000107 NCBI chr 1:246,973,447...247,024,019
Ensembl chr 1:246,973,436...247,027,527
JBrowse link
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALM1 calmodulin 1 IEA Ensembl GO_REF:0000107 NCBI chr 7:112,160,823...112,171,754
Ensembl chr 7:112,154,880...112,171,744
JBrowse link
G CALM2 calmodulin 2 ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chr 3:93,371,765...93,386,378
Ensembl chr 3:93,372,045...93,438,068
JBrowse link
G CALM3 calmodulin 3 IEA Ensembl GO_REF:0000107 NCBI chr 6:52,506,979...52,516,704
Ensembl chr 6:52,506,674...52,516,703
JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta ISO PMID:12676813 BHF-UCL PMID:12676813 RGD:10047271 NCBI chr 8:108,916,019...109,221,317
Ensembl chr 8:108,710,660...109,228,901
JBrowse link
G CASQ1 calsequestrin 1 ISO (MGI:3814667|PMID:17627988)
(MGI:2449410|PMID:12419813)
MGI PMID:12419813, PMID:17627988 MGI:2449410, MGI:3814667 NCBI chr 4:90,276,752...90,288,990
Ensembl chr 4:90,276,754...90,288,011
JBrowse link
G CASQ2 calsequestrin 2 ISO (PMID:15041652)
(MGI:3689635|PMID:16932808)
BHF-UCL
UniProt
PMID:15041652, PMID:16932808 MGI:3689635 NCBI chr 4:104,918,204...104,984,019
Ensembl chr 4:104,918,501...104,999,787
JBrowse link
G CHD7 chromodomain helicase DNA binding protein 7 IEA Ensembl GO_REF:0000107 NCBI chr 4:72,572,455...72,754,443
Ensembl chr 4:72,571,874...72,754,432
JBrowse link
G CLIC2 chloride intracellular channel 2 IEA Ensembl GO_REF:0000107 NCBI chr  X:125,546,451...125,560,059
Ensembl chr  X:125,546,467...125,570,523
JBrowse link
G DHRS7C dehydrogenase/reductase 7C IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:54,647,773...54,661,442
Ensembl chr12:54,639,773...54,661,662
JBrowse link
G DMD dystrophin ISO (MGI:4420848|PMID:20080623), (MGI:5487906|PMID:23263329) BHF-UCL PMID:20080623, PMID:23263329 MGI:4420848, MGI:5487906 NCBI chr  X:27,028,223...29,650,728
Ensembl chr  X:27,028,223...29,181,689
JBrowse link
G FKBP1B FKBP prolyl isomerase 1B IEA Ensembl GO_REF:0000107 NCBI chr 3:114,623,529...114,636,200
Ensembl chr 3:114,623,529...114,634,628
JBrowse link
G GSTO1 glutathione S-transferase omega 1 ISO (PMID:11035031) BHF-UCL PMID:11035031 NCBI chr14:115,206,434...115,216,624
Ensembl chr14:115,206,188...115,216,613
JBrowse link
G HRC histidine rich calcium binding protein IEA Ensembl GO_REF:0000107 NCBI chr 6:54,337,348...54,341,638
Ensembl chr 6:54,337,347...54,341,626
JBrowse link
G METTL21C methyltransferase like 21C IEA Ensembl GO_REF:0000107 NCBI chr11:71,008,854...71,021,640
Ensembl chr11:71,010,850...71,020,730
JBrowse link
G PDE4D phosphodiesterase 4D IEA Ensembl GO_REF:0000107 NCBI chr16:37,897,300...39,406,534
Ensembl chr16:37,897,300...39,154,586
JBrowse link
G PLN phospholamban ISO (MGI:3655341|PMID:9118481) MGI PMID:9118481 MGI:3655341 NCBI chr 1:43,449,354...43,458,925 JBrowse link
G TRDN triadin IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:39,180,544...39,567,245
Ensembl chr 1:39,180,879...39,567,240
JBrowse link
regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASQ1 calsequestrin 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:90,276,752...90,288,990
Ensembl chr 4:90,276,754...90,288,011
JBrowse link
G DMD dystrophin IEA Ensembl GO_REF:0000107 NCBI chr  X:27,028,223...29,650,728
Ensembl chr  X:27,028,223...29,181,689
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16548
    cellular process 15780
      negative regulation of cellular process 4869
        negative regulation of sequestering of calcium ion 122
          release of sequestered calcium ion into cytosol 121
            release of sequestered calcium ion into cytosol by endoplasmic reticulum 28
              release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 27
                regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum + 23
Path 2
Term Annotations click to browse term
  biological_process 16548
    biological regulation 12014
      regulation of biological quality 3986
        homeostatic process 1962
          cellular homeostasis 960
            cellular chemical homeostasis 878
              cellular ion homeostasis 673
                cellular cation homeostasis 660
                  cellular divalent inorganic cation homeostasis 508
                    cellular calcium ion homeostasis 480
                      regulation of cytosolic calcium ion concentration 379
                        positive regulation of cytosolic calcium ion concentration 334
                          calcium ion transport into cytosol 172
                            calcium ion transmembrane import into cytosol 149
                              release of sequestered calcium ion into cytosol 121
                                release of sequestered calcium ion into cytosol by endoplasmic reticulum 28
                                  release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 27
                                    regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum + 23
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.