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ONTOLOGY REPORT - ANNOTATIONS


Term:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
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Accession:GO:0014808 term browser browse the term
Definition:The process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.


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release of sequestered calcium ion into cytosol by sarcoplasmic reticulum term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl3 chemokine (C-C motif) ligand 3 ISO (PMID:19523456) UniProtKB PMID:19523456 NCBI chr11:83,647,843...83,649,378
Ensembl chr11:83,647,844...83,649,355
JBrowse link
G Ccr5 chemokine (C-C motif) receptor 5 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 9:124,121,543...124,127,183
Ensembl chr 9:124,121,543...124,147,699
JBrowse link
G Nol3 nucleolar protein 3 (apoptosis repressor with CARD domain) ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 8:105,276,145...105,281,939
Ensembl chr 8:105,276,140...105,281,939
JBrowse link
G Ryr1 ryanodine receptor 1, skeletal muscle ISO
IMP
(MGI:3764002|PMID:18003898) MGI
UniProt
PMID:18003898 GO_REF:0000096, MGI:3764002, MGI:4417868 NCBI chr 7:29,003,340...29,125,179
Ensembl chr 7:29,003,344...29,125,179
JBrowse link
G Ryr2 ryanodine receptor 2, cardiac IDA
ISO
IMP
(MGI:4442115|PMID:20226167)
(MGI:2182484|PMID:12089338)
BHF-UCL
MGI
PMID:12089338, PMID:20226167 GO_REF:0000096, MGI:2182484, MGI:4442115, MGI:4834177 NCBI chr13:11,553,099...12,106,945
Ensembl chr13:11,553,102...12,106,945
JBrowse link
G Tmem38a transmembrane protein 38A IGI (MGI:3715564|PMID:17611541) MGI PMID:17611541 MGI:3715564 NCBI chr 8:72,571,189...72,587,284
Ensembl chr 8:72,572,055...72,587,282
JBrowse link
G Tmem38b transmembrane protein 38B IGI (MGI:3715564|PMID:17611541) MGI PMID:17611541 MGI:3715564 NCBI chr 4:53,825,988...53,862,019
Ensembl chr 4:53,826,045...53,862,019
JBrowse link
G Trdn triadin IMP (MGI:3849347|PMID:19383796) MGI PMID:19383796 MGI:3849347 NCBI chr10:33,083,483...33,476,709
Ensembl chr10:33,080,554...33,476,709
JBrowse link
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2, brain IMP
IC
(MGI:5427070|PMID:21859974), (MGI:5430893|PMID:17178715)
(MGI:2449848|PMID:12571597)
BHF-UCL PMID:12571597, PMID:17178715, PMID:21859974 MGI:2449848, MGI:5427070, MGI:5430893 NCBI chr 3:126,921,607...127,500,347
Ensembl chr 3:126,921,612...127,499,350
JBrowse link
G Asph aspartate-beta-hydroxylase ISO (PMID:17400717) BHF-UCL PMID:17400717 NCBI chr 4:9,449,085...9,669,344
Ensembl chr 4:9,448,069...9,669,344
JBrowse link
G Casq2 calsequestrin 2 ISO
IDA
IBA
IMP
(MGI:1202079|PMID:9525981)
(MGI:6201960|PMID:21873635)
(MGI:3689635|PMID:16932808)
MGI
GO_Central
UniProt
PMID:9525981, PMID:16932808, PMID:21873635 GO_REF:0000096, MGI:1202079, MGI:3689635, MGI:4417868, MGI:4834177, MGI:6201960 NCBI chr 3:102,086,415...102,146,514
Ensembl chr 3:102,086,415...102,146,514
JBrowse link
G Dmd dystrophin, muscular dystrophy IMP (MGI:4420848|PMID:20080623) BHF-UCL PMID:20080623 MGI:4420848 NCBI chr  X:82,814,664...85,205,050
Ensembl chr  X:82,948,870...85,206,141
JBrowse link
G Fkbp1b FK506 binding protein 1b IBA
IMP
(MGI:6201960|PMID:21873635)
(MGI:3621834|PMID:12837242)
GO_Central
BHF-UCL
PMID:12837242, PMID:21873635 MGI:3621834, MGI:6201960 NCBI chr12:4,833,176...4,841,573
Ensembl chr12:4,833,174...4,841,591
JBrowse link
G Pln phospholamban IMP (MGI:82999|PMID:8831698) MGI PMID:8831698 MGI:82999 NCBI chr10:53,337,686...53,345,999
Ensembl chr10:53,337,667...53,345,987
JBrowse link
G Ryr2 ryanodine receptor 2, cardiac IGI (MGI:3621834|PMID:12837242) BHF-UCL PMID:12837242 MGI:3621834 NCBI chr13:11,553,099...12,106,945
Ensembl chr13:11,553,102...12,106,945
JBrowse link
G Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 ISO MGI GO_REF:0000096, MGI:4417868 NCBI chr17:81,373,105...81,738,387
Ensembl chr17:81,373,105...81,738,377
JBrowse link
G Tmem38a transmembrane protein 38A IGI (MGI:3715564|PMID:17611541) MGI PMID:17611541 MGI:3715564 NCBI chr 8:72,571,189...72,587,284
Ensembl chr 8:72,572,055...72,587,282
JBrowse link
G Tmem38b transmembrane protein 38B IGI (MGI:3715564|PMID:17611541) MGI PMID:17611541 MGI:3715564 NCBI chr 4:53,825,988...53,862,019
Ensembl chr 4:53,826,045...53,862,019
JBrowse link
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chr12:100,199,435...100,209,824
Ensembl chr12:100,199,435...100,209,814
JBrowse link
G Calm2 calmodulin 2 ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chr17:87,433,401...87,446,935
Ensembl chr12:100,199,435...100,209,814
Ensembl chr17:100,199,435...100,209,814
JBrowse link
G Calm3 calmodulin 3 ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chr 7:16,915,379...16,924,032
Ensembl chr 7:16,915,379...16,924,114
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II, delta ISO MGI GO_REF:0000096, MGI:4417868 NCBI chr 3:126,595,487...126,846,326
Ensembl chr 3:126,596,302...126,846,326
JBrowse link
G Casq1 calsequestrin 1 IDA
IMP
(MGI:2449410|PMID:12419813)
(MGI:3814667|PMID:17627988)
MGI PMID:12419813, PMID:17627988 MGI:2449410, MGI:3814667 NCBI chr 1:172,209,894...172,219,895
Ensembl chr 1:172,209,894...172,219,868
JBrowse link
G Casq2 calsequestrin 2 IMP (MGI:3689635|PMID:16932808) UniProt PMID:16932808 MGI:3689635 NCBI chr 3:102,086,415...102,146,514
Ensembl chr 3:102,086,415...102,146,514
JBrowse link
G Chd7 chromodomain helicase DNA binding protein 7 IMP (MGI:5694290|PMID:26102480) MGI PMID:26102480 MGI:5694290 NCBI chr 4:8,690,402...8,868,449
Ensembl chr 4:8,690,406...8,867,659
JBrowse link
G Dhrs7c dehydrogenase/reductase (SDR family) member 7C IDA
IBA
(MGI:5306721|PMID:21995425)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:21873635, PMID:21995425 MGI:5306721, MGI:6201960 NCBI chr11:67,798,271...67,816,002
Ensembl chr11:67,798,187...67,816,002
JBrowse link
G Dmd dystrophin, muscular dystrophy IMP (MGI:4420848|PMID:20080623), (MGI:5487906|PMID:23263329) BHF-UCL PMID:20080623, PMID:23263329 MGI:4420848, MGI:5487906 NCBI chr  X:82,814,664...85,205,050
Ensembl chr  X:82,948,870...85,206,141
JBrowse link
G Fkbp1b FK506 binding protein 1b ISO
IMP
(MGI:3028710|PMID:14592808), (MGI:5007884|PMID:19578067)
(MGI:3639647|PMID:16672364)
MGI PMID:14592808, PMID:16672364, PMID:19578067 GO_REF:0000096, MGI:3028710, MGI:3639647, MGI:4834177, MGI:5007884 NCBI chr12:4,833,176...4,841,573
Ensembl chr12:4,833,174...4,841,591
JBrowse link
G Gstm2 glutathione S-transferase, mu 2 ISO (PMID:17023043) BHF-UCL PMID:17023043 NCBI chr 3:107,981,702...107,986,420
Ensembl chr 3:107,981,702...107,986,453
JBrowse link
G Gstm7 glutathione S-transferase, mu 7 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 3:107,926,334...107,931,877
Ensembl chr 3:107,926,334...107,931,817
JBrowse link
G Gsto1 glutathione S-transferase omega 1 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr19:47,854,973...47,864,790
Ensembl chr19:47,854,970...47,864,790
JBrowse link
G Hrc histidine rich calcium binding protein ISO (PMID:24125847) BHF-UCL PMID:24125847 NCBI chr 7:45,335,269...45,338,973
Ensembl chr 7:45,335,290...45,338,974
JBrowse link
G Mettl21c methyltransferase like 21C IMP (MGI:5781029|PMID:24677265) MGI PMID:24677265 MGI:5781029 NCBI chr 1:44,009,399...44,042,620
Ensembl chr 1:44,009,408...44,020,034
JBrowse link
G Nol3 nucleolar protein 3 (apoptosis repressor with CARD domain) ISO MGI GO_REF:0000096, MGI:4417868 NCBI chr 8:105,276,145...105,281,939
Ensembl chr 8:105,276,140...105,281,939
JBrowse link
G Pde4d phosphodiesterase 4D, cAMP specific IMP (MGI:3690823|PMID:16213210) BHF-UCL PMID:16213210 MGI:3690823 NCBI chr13:108,654,177...109,955,969
Ensembl chr13:108,449,948...109,953,461
JBrowse link
G Pln phospholamban IMP (MGI:3655341|PMID:9118481) MGI PMID:9118481 MGI:3655341 NCBI chr10:53,337,686...53,345,999
Ensembl chr10:53,337,667...53,345,987
JBrowse link
G Trdn triadin IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096, MGI:4417868, MGI:6201960 NCBI chr10:33,083,483...33,476,709
Ensembl chr10:33,080,554...33,476,709
JBrowse link
regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casq1 calsequestrin 1 IMP
IBA
(MGI:3814667|PMID:17627988)
(MGI:6201960|PMID:21873635)
(MGI:5306707|PMID:22049211)
MGI
GO_Central
UniProt
PMID:17627988, PMID:21873635, PMID:22049211 MGI:3814667, MGI:5306707, MGI:6201960 NCBI chr 1:172,209,894...172,219,895
Ensembl chr 1:172,209,894...172,219,868
JBrowse link
G Dmd dystrophin, muscular dystrophy IMP (MGI:3837615|PMID:19198614) BHF-UCL PMID:19198614 MGI:3837615 NCBI chr  X:82,814,664...85,205,050
Ensembl chr  X:82,948,870...85,206,141
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23386
    cellular process 17420
      negative regulation of cellular process 5091
        negative regulation of sequestering of calcium ion 120
          release of sequestered calcium ion into cytosol 119
            release of sequestered calcium ion into cytosol by endoplasmic reticulum 29
              release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 28
                regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum + 25
Path 2
Term Annotations click to browse term
  biological_process 23386
    biological regulation 13124
      regulation of biological quality 4277
        homeostatic process 2083
          cellular homeostasis 1044
            cellular chemical homeostasis 925
              cellular ion homeostasis 707
                cellular cation homeostasis 693
                  cellular divalent inorganic cation homeostasis 529
                    cellular calcium ion homeostasis 501
                      regulation of cytosolic calcium ion concentration 396
                        positive regulation of cytosolic calcium ion concentration 351
                          calcium ion transport into cytosol 172
                            calcium ion transmembrane import into cytosol 148
                              release of sequestered calcium ion into cytosol 119
                                release of sequestered calcium ion into cytosol by endoplasmic reticulum 29
                                  release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 28
                                    regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum + 25
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.