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ONTOLOGY REPORT - ANNOTATIONS


Term:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
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Accession:GO:0014808 term browser browse the term
Definition:The process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.



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release of sequestered calcium ion into cytosol by sarcoplasmic reticulum term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl3 C-C motif chemokine ligand 3 involved_in ISO
ISS
(PMID:19523456)
GO_REF:0000024
RGD
UniProt
PMID:19523456 GO_REF:0000024 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 involved_in ISO (PMID:19523456) RGD PMID:19523456 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G ENSRNOG00000067970 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 3:99,631,867...99,979,128 JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO
IEA
(PMID:15509781)
GO_REF:0000107
RGD
Ensembl
PMID:15509781 GO_REF:0000107 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Ryr1 ryanodine receptor 1 involved_in ISS
IEA
IBA
ISO
IDA
GO_REF:0000024
GO_REF:0000118
GO_REF:0000033
(MGI:3764002|PMID:18003898)
PMID:11316255
UniProt
TreeGrafter
GO_Central
RGD
PMID:18003898 PMID:11316255 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 MGI:3764002, RGD:12903237 NCBI chr 1:84,292,578...84,423,824
Ensembl chr 1:84,292,578...84,423,812
JBrowse link
G Ryr2 ryanodine receptor 2 involved_in
acts_upstream_of_or_within
IEA
IBA
ISS
ISO
GO_REF:0000107
GO_REF:0000033
GO_REF:0000118
GO_REF:0000024
(PMID:12919952), (PMID:27733687), (PMID:33536282)
(MGI:2182484|PMID:12089338)
(MGI:4442115|PMID:20226167)
Ensembl
GO_Central
TreeGrafter
UniProt
RGD
PMID:12089338 PMID:12919952 PMID:20226167 PMID:27733687 PMID:33536282 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:2182484 MGI:4442115 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142
JBrowse link
G Tmem38a transmembrane protein 38a involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1098718 (MGI:3715564|PMID:17611541)
Ensembl
RGD
PMID:17611541 GO_REF:0000107 MGI:3715564 NCBI chr16:17,258,160...17,274,204
Ensembl chr16:17,258,164...17,273,415
JBrowse link
G Tmem38b transmembrane protein 38B acts_upstream_of_or_within ISO MGI:1921416 (MGI:3715564|PMID:17611541) RGD PMID:17611541 MGI:3715564 NCBI chr 5:68,460,304...68,496,026
Ensembl chr 5:68,460,304...68,496,025
JBrowse link
G Trdn triadin acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:3769415 (MGI:3849347|PMID:19383796)
GO_REF:0000107
RGD
Ensembl
PMID:19383796 GO_REF:0000107 MGI:3849347 NCBI chr 1:23,955,651...24,410,494
Ensembl chr 1:23,955,651...24,410,595
JBrowse link
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 involved_in ISO UniProtKB:Q8C8R3 (PMID:17178715)
(MGI:5427070|PMID:21859974), (MGI:5430893|PMID:17178715)
RGD PMID:17178715 PMID:21859974 MGI:5427070 MGI:5430893 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta involved_in IC PMID:12676813 BHF-UCL PMID:12676813 RGD:10047271 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178
JBrowse link
G Casq2 calsequestrin 2 involved_in
acts_upstream_of_or_within
ISO
IMP
IEA
IBA
(PMID:16601229), (PMID:16908766)
PMID:17569730
(MGI:3689635|PMID:16932808)
(MGI:1202079|PMID:9525981)
GO_REF:0000107
GO_REF:0000118
GO_REF:0000033
RGD
Ensembl
TreeGrafter
GO_Central
PMID:9525981 PMID:16601229 PMID:16908766 PMID:16932808 PMID:17569730 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:1202079 MGI:3689635, RGD:2314601 NCBI chr 2:189,526,003...189,582,276
Ensembl chr 2:189,525,960...189,582,267
JBrowse link
G Dmd dystrophin involved_in ISO (MGI:4420848|PMID:20080623) RGD PMID:20080623 MGI:4420848 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B involved_in ISO
IBA
IEA
(MGI:3621834|PMID:12837242)
GO_REF:0000033
GO_REF:0000118
RGD
GO_Central
TreeGrafter
PMID:12837242 GO_REF:0000033 GO_REF:0000118 MGI:3621834 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653
JBrowse link
G Pln phospholamban acts_upstream_of_or_within ISO MGI:2158357 (MGI:82999|PMID:8831698) RGD PMID:8831698 MGI:82999 NCBI chr20:32,629,537...32,639,559 JBrowse link
G Ryr2 ryanodine receptor 2 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:Q9Z2I2 (MGI:3621834|PMID:12837242)
Ensembl
RGD
PMID:12837242 GO_REF:0000107 MGI:3621834 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142
JBrowse link
G Slc8a1 solute carrier family 8 member A1 involved_in IDA PMID:21779914 BHF-UCL PMID:21779914 RGD:8554732 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628
JBrowse link
G Tmem38a transmembrane protein 38a involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1098718 (MGI:3715564|PMID:17611541)
Ensembl
RGD
PMID:17611541 GO_REF:0000107 MGI:3715564 NCBI chr16:17,258,160...17,274,204
Ensembl chr16:17,258,164...17,273,415
JBrowse link
G Tmem38b transmembrane protein 38B acts_upstream_of_or_within ISO MGI:1921416 (MGI:3715564|PMID:17611541) RGD PMID:17611541 MGI:3715564 NCBI chr 5:68,460,304...68,496,026
Ensembl chr 5:68,460,304...68,496,025
JBrowse link
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap6 A-kinase anchoring protein 6 involved_in IC PMID:12709444 BHF-UCL PMID:12709444 RGD:8554839 NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738
JBrowse link
G Calm1 calmodulin 1 involved_in ISO
IEA
(PMID:20226167)
GO_REF:0000107
RGD
Ensembl
PMID:20226167 GO_REF:0000107 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm2 calmodulin 2 involved_in ISO (PMID:20226167) RGD PMID:20226167 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287
JBrowse link
G Calm3 calmodulin 3 involved_in ISO (PMID:20226167) RGD PMID:20226167 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta involved_in IDA PMID:12676813 BHF-UCL PMID:12676813 RGD:10047271 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178
JBrowse link
G Casq1 calsequestrin 1 acts_upstream_of_or_within ISO MGI:3530841 (MGI:2449410|PMID:12419813), (MGI:3814667|PMID:17627988) RGD PMID:12419813 PMID:17627988 MGI:2449410 MGI:3814667 NCBI chr13:84,670,648...84,680,339
Ensembl chr13:84,670,649...84,680,339
JBrowse link
G Casq2 calsequestrin 2 involved_in ISO (PMID:15041652)
(MGI:3689635|PMID:16932808)
RGD PMID:15041652 PMID:16932808 MGI:3689635 NCBI chr 2:189,526,003...189,582,276
Ensembl chr 2:189,525,960...189,582,267
JBrowse link
G Chd7 chromodomain helicase DNA binding protein 7 acts_upstream_of_or_within ISO MGI:2176467|MGI:4433295 (MGI:5694290|PMID:26102480) RGD PMID:26102480 MGI:5694290 NCBI chr 5:21,812,007...21,995,358
Ensembl chr 5:21,812,070...21,995,358
JBrowse link
G Clic2 chloride intracellular channel 2 involved_in ISO (PMID:15147738), (PMID:15916532) RGD PMID:15147738 PMID:15916532 NCBI chr20:149,337...164,375
Ensembl chr20:148,907...164,355
JBrowse link
G Dhrs7c dehydrogenase/reductase 7C acts_upstream_of_or_within
involved_in
ISO
ISS
(MGI:5306721|PMID:21995425)
GO_REF:0000024
RGD
UniProt
PMID:21995425 GO_REF:0000024 MGI:5306721 NCBI chr10:52,495,262...52,513,338
Ensembl chr10:52,495,262...52,513,338
JBrowse link
G Dmd dystrophin involved_in ISO (MGI:4420848|PMID:20080623), (MGI:5487906|PMID:23263329) RGD PMID:20080623 PMID:23263329 MGI:4420848 MGI:5487906 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B involved_in
acts_upstream_of_or_within
ISO (PMID:20431056)
MGI:2182644|MGI:3623214 (MGI:3028710|PMID:14592808), (MGI:3639647|PMID:16672364), (MGI:5007884|PMID:19578067)
RGD PMID:14592808 PMID:16672364 PMID:19578067 PMID:20431056 MGI:3028710 MGI:3639647 MGI:5007884 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653
JBrowse link
G Gstm2 glutathione S-transferase mu 2 involved_in ISO (PMID:17023043) RGD PMID:17023043 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gstm7 glutathione S-transferase, mu 7 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:195,566,701...195,572,149
Ensembl chr 2:195,566,701...195,572,203
JBrowse link
G Gsto1 glutathione S-transferase omega 1 involved_in ISO (PMID:11035031) RGD PMID:11035031 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
JBrowse link
G Hrc histidine rich calcium binding protein involved_in ISO UniProtKB:B9EIW1 (PMID:24125847) RGD PMID:24125847 NCBI chr 1:95,813,262...95,816,987
Ensembl chr 1:95,813,253...95,816,984
JBrowse link
G Mettl21c methyltransferase 21C, AARS1 lysine acts_upstream_of_or_within ISO (MGI:5781029|PMID:24677265) RGD PMID:24677265 MGI:5781029 NCBI chr 9:46,130,451...46,145,128
Ensembl chr 9:46,134,001...46,145,112
JBrowse link
G Mir1 microRNA 1 involved_in
acts_upstream_of
ISO (PMID:19131648) RGD PMID:19131648 NCBI chr18:1,887,537...1,887,623 JBrowse link
G Mir1b microRNA 1b involved_in
acts_upstream_of
ISO (PMID:19131648) RGD PMID:19131648 NCBI chr 3:167,487,117...167,487,201
Ensembl chr 3:167,487,117...167,487,201
JBrowse link
G Nol3 nucleolar protein 3 involved_in IMP PMID:23382383 UniProt PMID:23382383 RGD:10047354 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Pde4d phosphodiesterase 4D involved_in ISO (MGI:3690823|PMID:16213210) RGD PMID:16213210 MGI:3690823 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884
JBrowse link
G Pln phospholamban acts_upstream_of_or_within ISO MGI:2158357 (MGI:3655341|PMID:9118481) RGD PMID:9118481 MGI:3655341 NCBI chr20:32,629,537...32,639,559 JBrowse link
G Trdn triadin involved_in IMP
IBA
IEA
ISO
GO_REF:0000033
GO_REF:0000118
(PMID:15041652)
GO_Central
TreeGrafter
RGD
PMID:15041652 PMID:17569730 GO_REF:0000033 GO_REF:0000118, RGD:2314601 NCBI chr 1:23,955,651...24,410,494
Ensembl chr 1:23,955,651...24,410,595
JBrowse link
regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casq1 calsequestrin 1 involved_in
acts_upstream_of_or_within
ISS
ISO
IBA
GO_REF:0000024
MGI:3530841 (MGI:3814667|PMID:17627988)
(MGI:5306707|PMID:22049211)
GO_REF:0000033
UniProt
RGD
GO_Central
PMID:17627988 PMID:22049211 GO_REF:0000024 GO_REF:0000033 MGI:3814667 MGI:5306707 NCBI chr13:84,670,648...84,680,339
Ensembl chr13:84,670,649...84,680,339
JBrowse link
G Dmd dystrophin involved_in ISO (MGI:3837615|PMID:19198614) RGD PMID:19198614 MGI:3837615 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20325
    negative regulation of biological process 5774
      negative regulation of cellular process 5409
        negative regulation of sequestering of calcium ion 131
          release of sequestered calcium ion into cytosol 130
            release of sequestered calcium ion into cytosol by endoplasmic reticulum 34
              release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 33
                regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum + 29
Path 2
Term Annotations click to browse term
  biological_process 20325
    homeostatic process 1968
      cellular homeostasis 972
        intracellular chemical homeostasis 865
          intracellular monoatomic ion homeostasis 590
            intracellular monoatomic cation homeostasis 579
              intracellular calcium ion homeostasis 339
                sequestering of calcium ion 135
                  regulation of sequestering of calcium ion 133
                    negative regulation of sequestering of calcium ion 131
                      release of sequestered calcium ion into cytosol 130
                        release of sequestered calcium ion into cytosol by endoplasmic reticulum 34
                          release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 33
                            regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum + 29
paths to the root