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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of muscle hypertrophy
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Accession:GO:0014742 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of muscle hypertrophy.


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positive regulation of cardiac muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adk adenosine kinase IMP RGD PMID:21335462 RGD:6482642 NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510 		JBrowse link
G Adra1a adrenoceptor alpha 1A acts_upstream_of_or_within ISO (MGI:5888970|PMID:27994061) RGD PMID:27994061 MGI:5888970 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Agt angiotensinogen involved_in IDA PMID:8348686 BHF-UCL PMID:8348686 RGD:8553767 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Becn1 beclin 1 acts_upstream_of_or_within ISO MGI:2683833 (MGI:5888970|PMID:27994061) RGD PMID:27994061 MGI:5888970 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bmp10 bone morphogenetic protein 10 involved_in ISO
IEA
IMP		 (PMID:17921333)
GO_REF:0000107		 RGD
Ensembl		 PMID:17921333 PMID:17921333 GO_REF:0000107, RGD:2302083 NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta involved_in ISO
ISS		 (PMID:17179159)
GO_REF:0000024		 RGD
UniProt		 PMID:17179159 GO_REF:0000024 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178 		JBrowse link
G Cdk9 cyclin-dependent kinase 9 IMP RGD PMID:20081228 RGD:9698419 NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410 		JBrowse link
G Ece1 endothelin converting enzyme 1 IMP RGD PMID:20099522 RGD:7243873 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371 		JBrowse link
G Edn1 endothelin 1 involved_in ISO (PMID:12847114) RGD PMID:12847114 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in ISO
IEA		 UniProtKB:P63328|UniProtKB:Q02078 (PMID:24161931)
GO_REF:0000107		 RGD
Ensembl		 PMID:24161931 GO_REF:0000107 NCBI chr16:32,917,826...32,919,880
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO (PMID:19654000), (PMID:19933931) RGD PMID:19654000 PMID:19933931 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Mef2a myocyte enhancer factor 2a involved_in ISO
IEA		 UniProtKB:P61296 (PMID:24161931)
GO_REF:0000107		 RGD
Ensembl		 PMID:24161931 GO_REF:0000107 NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in IMP PMID:19654000 UniProt PMID:19654000 RGD:5131609 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mtpn myotrophin involved_in ISO
IMP		 (PMID:10329199)
PMID:18693253		 RGD PMID:10329199 PMID:18693253 RGD:8553542 NCBI chr 4:64,159,273...64,186,686
Ensembl chr 4:64,157,641...64,186,724 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in IMP PMID:25625556 UniProt PMID:25625556 RGD:10054073 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in IMP PMID:25625556 UniProt PMID:25625556 RGD:10054073 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pde5a phosphodiesterase 5A involved_in ISO (MGI:3836877|PMID:19127022) RGD PMID:19127022 MGI:3836877 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701 		JBrowse link
G Pde9a phosphodiesterase 9A involved_in ISS
ISO		 GO_REF:0000024
(MGI:5634842|PMID:25799991)		 UniProt
RGD		 PMID:25799991 GO_REF:0000024 MGI:5634842 NCBI chr20:9,469,809...9,562,949
Ensembl chr20:9,469,848...9,562,948 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in ISO RNAcentral:URS0000021B51_10090|UniProtKB:P61296 (MGI:5562625|PMID:24161931), (MGI:5784969|PMID:24657879) RGD PMID:24161931 PMID:24657879 MGI:5562625 MGI:5784969 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Prkca protein kinase C, alpha involved_in IDA PMID:11864993 UniProt PMID:11864993 RGD:8554603 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Ptk2 protein tyrosine kinase 2 acts_upstream_of_or_within ISO (MGI:5888970|PMID:27994061) RGD PMID:27994061 MGI:5888970 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:28679962)		 Ensembl
RGD		 PMID:28679962 GO_REF:0000107 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in IMP
ISO		 PMID:28679962
(MGI:6158813|PMID:28679962)		 RGD PMID:28679962 PMID:28679962 MGI:6158813, RGD:13601991 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 involved_in ISO (PMID:21359875) RGD PMID:21359875 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624 		JBrowse link
G Twf1 twinfilin actin-binding protein 1 involved_in ISO (MGI:5882879|PMID:20571053) RGD PMID:20571053 MGI:5882879 NCBI chr 7:125,715,938...125,727,834
Ensembl chr 7:125,716,015...125,727,894 		JBrowse link
positive regulation of cardiac muscle hypertrophy in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in ISO (MGI:3848765|PMID:19287093) RGD PMID:19287093 MGI:3848765 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 involved_in ISO (PMID:19287093) RGD PMID:19287093 NCBI chr 2:119,481,313...119,619,333
Ensembl chr 2:119,481,400...119,558,855 		JBrowse link
positive regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:18194989 RGD:5129139 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Akap6 A-kinase anchoring protein 6 IMP
IDA		 RGD PMID:21550986 PMID:16306226 RGD:6902940, RGD:2312613 NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738 		JBrowse link
G Ccn4 cellular communication network factor 4 IMP RGD PMID:21376054 RGD:5129173 NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248 		JBrowse link
G Ddx39b DExD-box helicase 39B IMP RGD PMID:20116367 RGD:10401141 NCBI chr20:3,547,702...3,585,064
Ensembl chr20:3,572,056...3,584,996 		JBrowse link
G Edn1 endothelin 1 involved_in ISO RNAcentral:URS000006FDD4_9606|RNAcentral:URS000013D17D_9606 (PMID:24117217) RGD PMID:24117217 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ep300 E1A binding protein p300 IMP RGD PMID:12724418 RGD:2312280 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Fdps farnesyl diphosphate synthase IMP RGD PMID:19716825 RGD:2316294 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776 		JBrowse link
G Hamp hepcidin antimicrobial peptide IMP RGD PMID:24424338 RGD:11041632 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA		 RNAcentral:URS000006FDD4_9606|RNAcentral:URS000013D17D_9606 (PMID:24117217)
GO_REF:0000107		 RGD
Ensembl		 PMID:24117217 GO_REF:0000107 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Mir19a microRNA 19a involved_in ISO UniProtKB:P05019 (PMID:24117217) RGD PMID:24117217 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993 		JBrowse link
G Mir19b1 microRNA 19b-1 involved_in ISO UniProtKB:P05019 (PMID:24117217) RGD PMID:24117217 NCBI chr15:92,181,214...92,181,300
Ensembl chr15:92,181,214...92,181,300 		JBrowse link
G Mir19b2 microRNA 19b-2 involved_in ISO UniProtKB:P05019 (PMID:24117217) RGD PMID:24117217 NCBI chr  X:132,422,072...132,422,167
Ensembl chr  X:132,422,072...132,422,167 		JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:21318349 PMID:21933187 RGD:10040977, RGD:10040978 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IMP RGD PMID:22989630 RGD:7174736 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Parp2 poly (ADP-ribose) polymerase 2 IMP RGD PMID:23261455 RGD:13514044 NCBI chr15:24,034,069...24,044,340
Ensembl chr15:24,034,106...24,044,338 		JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 IMP RGD PMID:23487407 RGD:8693424 NCBI chr 8:19,189,408...19,200,785
Ensembl chr 8:19,189,373...19,200,785 		JBrowse link
G Sirt1 sirtuin 1 IMP RGD PMID:25281201 RGD:13514043 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 IDA RGD PMID:21325829 RGD:9681466 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733 		JBrowse link
G Trip10 thyroid hormone receptor interactor 10 IMP RGD PMID:23915320 RGD:11535145 NCBI chr 9:2,133,085...2,147,795
Ensembl chr 9:2,133,671...2,147,799 		JBrowse link
positive regulation of skeletal muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:23470307 RGD:10041029 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Mymk myomaker, myoblast fusion factor involved_in ISO (MGI:6116777|PMID:28186492) RGD PMID:28186492 MGI:6116777 NCBI chr 3:10,388,361...10,397,364
Ensembl chr 3:10,388,361...10,397,343 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19903
    positive regulation of biological process 6770
      positive regulation of multicellular organismal process 1907
        positive regulation of muscle hypertrophy 44
          positive regulation of cardiac muscle hypertrophy + 43
          positive regulation of skeletal muscle hypertrophy 2
          positive regulation of smooth muscle hypertrophy 0
Path 2
Term Annotations click to browse term
  biological_process 19903
    biological regulation 13542
      regulation of biological process 13094
        regulation of multicellular organismal process 3380
          regulation of system process 698
            regulation of muscle system process 279
              regulation of muscle hypertrophy 83
                positive regulation of muscle hypertrophy 44
                  positive regulation of cardiac muscle hypertrophy + 43
                  positive regulation of skeletal muscle hypertrophy 2
                  positive regulation of smooth muscle hypertrophy 0
paths to the root