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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of muscle hypertrophy
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Accession:GO:0014742 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of muscle hypertrophy.

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positive regulation of cardiac muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adk adenosine kinase IMP RGD PMID:21335462 RGD:6482642 NCBI chr15:3,033,535...3,435,888
Ensembl chr15:3,033,495...3,435,888 		JBrowse link
G Adra1a adrenoceptor alpha 1A ISO (MGI:5888970|PMID:27994061) RGD PMID:27994061 MGI:5888970 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451 		JBrowse link
G Agt angiotensinogen IDA PMID:8348686 BHF-UCL PMID:8348686 RGD:8553767 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Becn1 beclin 1 ISO MGI:2683833 (MGI:5888970|PMID:27994061) RGD PMID:27994061 MGI:5888970 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297 		JBrowse link
G Bmp10 bone morphogenetic protein 10 involved_in ISO
IEA
IMP		 (PMID:17921333)
GO_REF:0000107		 RGD
Ensembl		 PMID:17921333, PMID:17921333, PMID:17921333 GO_REF:0000107, RGD:2302083, RGD:2302083 NCBI chr 4:119,224,906...119,230,534
Ensembl chr 4:119,225,040...119,230,728 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta involved_in ISO
ISS		 (PMID:17179159)
GO_REF:0000024		 RGD
UniProt		 PMID:17179159 GO_REF:0000024 NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039 		JBrowse link
G Cdk9 cyclin-dependent kinase 9 IMP RGD PMID:20081228 RGD:9698419 NCBI chr 3:11,742,269...11,747,117
Ensembl chr 3:11,742,266...11,747,113 		JBrowse link
G Ece1 endothelin converting enzyme 1 IMP RGD PMID:20099522 RGD:7243873 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671 		JBrowse link
G Edn1 endothelin 1 involved_in ISO (PMID:12847114) RGD PMID:12847114 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in ISO
IEA		 UniProtKB:P63328|UniProtKB:Q02078 (PMID:24161931)
GO_REF:0000107		 RGD
Ensembl		 PMID:24161931 GO_REF:0000107 NCBI chr16:36,371,489...36,373,551
Ensembl chr16:36,371,489...36,373,546 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO (PMID:19654000), (PMID:19933931) RGD PMID:19654000 PMID:19933931 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609 		JBrowse link
G Mef2a myocyte enhancer factor 2a involved_in ISO
IEA		 UniProtKB:P61296 (PMID:24161931)
GO_REF:0000107		 RGD
Ensembl		 PMID:24161931 GO_REF:0000107 NCBI chr 1:128,207,715...128,341,681
Ensembl chr 1:128,209,971...128,341,263 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in IMP PMID:19654000 UniProt PMID:19654000, PMID:19654000 RGD:5131609, RGD:5131609 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787 		JBrowse link
G Mtpn myotrophin involved_in IMP
ISO		 PMID:18693253
(PMID:10329199)		 RGD PMID:10329199, PMID:18693253, PMID:18693253 RGD:8553542, RGD:8553542 NCBI chr 4:63,012,009...63,039,422
Ensembl chr 4:63,012,011...63,039,422 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in IMP PMID:25625556 UniProt PMID:25625556, PMID:25625556 RGD:10054073, RGD:10054073 NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in IMP PMID:25625556 UniProt PMID:25625556, PMID:25625556 RGD:10054073, RGD:10054073 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
G Pde5a phosphodiesterase 5A involved_in IEA
ISO		 GO_REF:0000107
(MGI:3836877|PMID:19127022)		 Ensembl
RGD		 PMID:19127022 GO_REF:0000107 MGI:3836877 NCBI chr 2:226,899,604...227,044,916
Ensembl chr 2:226,900,619...227,041,576 		JBrowse link
G Pde9a phosphodiesterase 9A involved_in ISS
ISO		 GO_REF:0000024
(MGI:5634842|PMID:25799991)		 UniProt
RGD		 PMID:25799991 GO_REF:0000024 MGI:5634842 NCBI chr20:10,123,624...10,216,325
Ensembl chr20:10,123,651...10,216,548 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha ISO RNAcentral:URS0000021B51_10090|UniProtKB:P61296 (MGI:5562625|PMID:24161931), (MGI:5784969|PMID:24657879) RGD PMID:24161931 PMID:24657879 MGI:5562625 MGI:5784969 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854 		JBrowse link
G Prkca protein kinase C, alpha involved_in IDA PMID:11864993 UniProt PMID:11864993, PMID:11864993 RGD:8554603, RGD:8554603 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947 		JBrowse link
G Ptk2 protein tyrosine kinase 2 ISO (MGI:5888970|PMID:27994061) RGD PMID:27994061 MGI:5888970 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:28679962)		 Ensembl
RGD		 PMID:28679962 GO_REF:0000107 NCBI chr18:1,273,490...1,390,790
Ensembl chr18:1,273,453...1,390,190 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in IMP
ISO		 PMID:28679962
(MGI:6158813|PMID:28679962)		 RGD PMID:28679962, PMID:28679962, PMID:28679962 MGI:6158813, RGD:13601991, RGD:13601991 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 involved_in ISO (PMID:21359875) RGD PMID:21359875 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316 		JBrowse link
G Twf1 twinfilin actin-binding protein 1 ISO (MGI:5882879|PMID:20571053) RGD PMID:20571053 MGI:5882879 NCBI chr 7:135,838,647...135,850,542
Ensembl chr 7:135,838,648...135,850,542 		JBrowse link
positive regulation of cardiac muscle hypertrophy in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp3ca protein phosphatase 3 catalytic subunit alpha ISO (MGI:3848765|PMID:19287093) RGD PMID:19287093 MGI:3848765 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854 		JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 involved_in ISO
IEA		 (PMID:19287093)
GO_REF:0000107		 RGD
Ensembl		 PMID:19287093 GO_REF:0000107 NCBI chr 2:123,329,954...123,467,574
Ensembl chr 2:123,329,875...123,407,496 		JBrowse link
positive regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:18194989 RGD:5129139 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985 		JBrowse link
G Akap6 A-kinase anchoring protein 6 IMP
IDA		 RGD PMID:21550986, PMID:16306226 RGD:6902940, RGD:2312613 NCBI chr 6:73,553,111...73,991,992
Ensembl chr 6:73,553,210...73,990,534 		JBrowse link
G Ccn4 cellular communication network factor 4 IMP RGD PMID:21376054 RGD:5129173 NCBI chr 7:107,695,227...107,723,759
Ensembl chr 7:107,695,215...107,723,772 		JBrowse link
G Ddx39b DExD-box helicase 39B IMP RGD PMID:20116367 RGD:10401141 NCBI chr20:4,806,103...4,818,600
Ensembl chr20:4,806,108...4,818,568 		JBrowse link
G Edn1 endothelin 1 involved_in ISO RNAcentral:URS000006FDD4_9606|RNAcentral:URS000013D17D_9606 (PMID:24117217) RGD PMID:24117217 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G Ep300 E1A binding protein p300 IMP RGD PMID:12724418 RGD:2312280 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296 		JBrowse link
G Fdps farnesyl diphosphate synthase IMP RGD PMID:19716825 RGD:2316294 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219 		JBrowse link
G Hamp hepcidin antimicrobial peptide IMP RGD PMID:24424338 RGD:11041632 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA		 RNAcentral:URS000006FDD4_9606|RNAcentral:URS000013D17D_9606 (PMID:24117217)
GO_REF:0000107		 RGD
Ensembl		 PMID:24117217 GO_REF:0000107 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609 		JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:21318349, PMID:21933187 RGD:10040977, RGD:10040978 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IMP RGD PMID:22989630 RGD:7174736 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647 		JBrowse link
G Parp2 poly (ADP-ribose) polymerase 2 IMP RGD PMID:23261455 RGD:13514044 NCBI chr15:27,739,416...27,749,650
Ensembl chr15:27,739,251...27,749,648 		JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 IMP RGD PMID:23487407 RGD:8693424 NCBI chr 8:21,669,236...21,680,615
Ensembl chr 8:21,669,236...21,680,615 		JBrowse link
G Sirt1 sirtuin 1 IMP RGD PMID:25281201 RGD:13514043 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 IDA RGD PMID:21325829 RGD:9681466 NCBI chr16:49,266,903...49,270,698
Ensembl chr16:49,266,903...49,270,698 		JBrowse link
G Trip10 thyroid hormone receptor interactor 10 IMP RGD PMID:23915320 RGD:11535145 NCBI chr 9:9,689,214...9,702,353
Ensembl chr 9:9,689,475...9,702,306 		JBrowse link
positive regulation of skeletal muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:23470307 RGD:10041029 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967 		JBrowse link
G Mymk myomaker, myoblast fusion factor ISO (MGI:6116777|PMID:28186492) RGD PMID:28186492 MGI:6116777 NCBI chr 3:5,608,243...5,617,689
Ensembl chr 3:5,608,243...5,617,225 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20078
    positive regulation of biological process 6624
      positive regulation of multicellular organismal process 1654
        positive regulation of muscle hypertrophy 41
          positive regulation of cardiac muscle hypertrophy + 40
          positive regulation of skeletal muscle hypertrophy 2
          positive regulation of smooth muscle hypertrophy 0
Path 2
Term Annotations click to browse term
  biological_process 20078
    biological regulation 13898
      regulation of biological process 13140
        regulation of multicellular organismal process 2925
          regulation of system process 655
            regulation of muscle system process 267
              regulation of muscle hypertrophy 76
                positive regulation of muscle hypertrophy 41
                  positive regulation of cardiac muscle hypertrophy + 40
                  positive regulation of skeletal muscle hypertrophy 2
                  positive regulation of smooth muscle hypertrophy 0
paths to the root