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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of muscle hypertrophy
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Accession:GO:0014742 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of muscle hypertrophy.



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positive regulation of cardiac muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adk adenosine kinase IMP RGD PMID:21335462 RGD:6482642 NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510
JBrowse link
G Adra1a adrenoceptor alpha 1A acts_upstream_of_or_within ISO (MGI:5888970|PMID:27994061) RGD PMID:27994061 MGI:5888970 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
JBrowse link
G Agt angiotensinogen involved_in IDA PMID:8348686 BHF-UCL PMID:8348686 RGD:8553767 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Becn1 beclin 1 acts_upstream_of_or_within ISO MGI:2683833 (MGI:5888970|PMID:27994061) RGD PMID:27994061 MGI:5888970 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bmp10 bone morphogenetic protein 10 involved_in ISO
IEA
IMP
(PMID:17921333)
GO_REF:0000107
RGD
Ensembl
PMID:17921333 PMID:17921333 GO_REF:0000107, RGD:2302083 NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta involved_in ISO
ISS
(PMID:17179159)
GO_REF:0000024
RGD
UniProt
PMID:17179159 GO_REF:0000024 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178
JBrowse link
G Cdk9 cyclin-dependent kinase 9 IMP RGD PMID:20081228 RGD:9698419 NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410
JBrowse link
G Ece1 endothelin converting enzyme 1 IMP RGD PMID:20099522 RGD:7243873 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371
JBrowse link
G Edn1 endothelin 1 involved_in ISO (PMID:12847114) RGD PMID:12847114 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in ISO
IEA
UniProtKB:P63328|UniProtKB:Q02078 (PMID:24161931)
GO_REF:0000107
RGD
Ensembl
PMID:24161931 GO_REF:0000107 NCBI chr16:32,917,826...32,919,880
Ensembl chr16:32,917,823...32,919,891
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO (PMID:19654000), (PMID:19933931) RGD PMID:19654000 PMID:19933931 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Mef2a myocyte enhancer factor 2a involved_in ISO
IEA
UniProtKB:P61296 (PMID:24161931)
GO_REF:0000107
RGD
Ensembl
PMID:24161931 GO_REF:0000107 NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948
JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in IMP PMID:19654000 UniProt PMID:19654000 RGD:5131609 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Mtpn myotrophin involved_in ISO
IMP
(PMID:10329199)
PMID:18693253
RGD PMID:10329199 PMID:18693253 RGD:8553542 NCBI chr 4:64,159,273...64,186,686
Ensembl chr 4:64,157,641...64,186,724
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in IMP PMID:25625556 UniProt PMID:25625556 RGD:10054073 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in IMP PMID:25625556 UniProt PMID:25625556 RGD:10054073 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pde5a phosphodiesterase 5A involved_in IEA
ISO
GO_REF:0000107
(MGI:3836877|PMID:19127022)
Ensembl
RGD
PMID:19127022 GO_REF:0000107 MGI:3836877 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
JBrowse link
G Pde9a phosphodiesterase 9A involved_in ISS
ISO
GO_REF:0000024
(MGI:5634842|PMID:25799991)
UniProt
RGD
PMID:25799991 GO_REF:0000024 MGI:5634842 NCBI chr20:9,469,809...9,562,949
Ensembl chr20:9,469,848...9,562,948
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in ISO RNAcentral:URS0000021B51_10090|UniProtKB:P61296 (MGI:5562625|PMID:24161931), (MGI:5784969|PMID:24657879) RGD PMID:24161931 PMID:24657879 MGI:5562625 MGI:5784969 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Prkca protein kinase C, alpha involved_in IDA PMID:11864993 UniProt PMID:11864993 RGD:8554603 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Ptk2 protein tyrosine kinase 2 acts_upstream_of_or_within ISO (MGI:5888970|PMID:27994061) RGD PMID:27994061 MGI:5888970 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:28679962)
Ensembl
RGD
PMID:28679962 GO_REF:0000107 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in IMP
ISO
PMID:28679962
(MGI:6158813|PMID:28679962)
RGD PMID:28679962 PMID:28679962 MGI:6158813, RGD:13601991 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031
JBrowse link
G Slc9a1 solute carrier family 9 member A1 involved_in ISO (PMID:21359875) RGD PMID:21359875 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624
JBrowse link
G Twf1 twinfilin actin-binding protein 1 involved_in ISO (MGI:5882879|PMID:20571053) RGD PMID:20571053 MGI:5882879 NCBI chr 7:125,715,938...125,727,834
Ensembl chr 7:125,716,015...125,727,894
JBrowse link
positive regulation of cardiac muscle hypertrophy in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in ISO (MGI:3848765|PMID:19287093) RGD PMID:19287093 MGI:3848765 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 involved_in IEA
ISO
GO_REF:0000107
(PMID:19287093)
Ensembl
RGD
PMID:19287093 GO_REF:0000107 NCBI chr 2:119,481,313...119,619,333
Ensembl chr 2:119,481,400...119,558,855
JBrowse link
positive regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:18194989 RGD:5129139 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Akap6 A-kinase anchoring protein 6 IMP
IDA
RGD PMID:21550986 PMID:16306226 RGD:6902940, RGD:2312613 NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738
JBrowse link
G Ccn4 cellular communication network factor 4 IMP RGD PMID:21376054 RGD:5129173 NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248
JBrowse link
G Ddx39b DExD-box helicase 39B IMP RGD PMID:20116367 RGD:10401141 NCBI chr20:3,547,702...3,585,064
Ensembl chr20:3,572,056...3,584,996
JBrowse link
G Edn1 endothelin 1 involved_in ISO RNAcentral:URS000006FDD4_9606|RNAcentral:URS000013D17D_9606 (PMID:24117217) RGD PMID:24117217 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ep300 E1A binding protein p300 IMP RGD PMID:12724418 RGD:2312280 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Fdps farnesyl diphosphate synthase IMP RGD PMID:19716825 RGD:2316294 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Hamp hepcidin antimicrobial peptide IMP RGD PMID:24424338 RGD:11041632 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA
RNAcentral:URS000006FDD4_9606|RNAcentral:URS000013D17D_9606 (PMID:24117217)
GO_REF:0000107
RGD
Ensembl
PMID:24117217 GO_REF:0000107 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:21318349 PMID:21933187 RGD:10040977, RGD:10040978 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IMP RGD PMID:22989630 RGD:7174736 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Parp2 poly (ADP-ribose) polymerase 2 IMP RGD PMID:23261455 RGD:13514044 NCBI chr15:24,034,069...24,044,340
Ensembl chr15:24,034,106...24,044,338
JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 IMP RGD PMID:23487407 RGD:8693424 NCBI chr 8:19,189,408...19,200,785
Ensembl chr 8:19,189,373...19,200,785
JBrowse link
G Sirt1 sirtuin 1 IMP RGD PMID:25281201 RGD:13514043 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc25a4 solute carrier family 25 member 4 IDA RGD PMID:21325829 RGD:9681466 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
G Trip10 thyroid hormone receptor interactor 10 IMP RGD PMID:23915320 RGD:11535145 NCBI chr 9:2,133,085...2,147,795
Ensembl chr 9:2,133,671...2,147,799
JBrowse link
positive regulation of skeletal muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:23470307 RGD:10041029 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mymk myomaker, myoblast fusion factor involved_in ISO (MGI:6116777|PMID:28186492) RGD PMID:28186492 MGI:6116777 NCBI chr 3:10,388,361...10,397,364
Ensembl chr 3:10,388,361...10,397,343
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    positive regulation of biological process 6686
      positive regulation of multicellular organismal process 1672
        positive regulation of muscle hypertrophy 41
          positive regulation of cardiac muscle hypertrophy + 40
          positive regulation of skeletal muscle hypertrophy 2
          positive regulation of smooth muscle hypertrophy 0
Path 2
Term Annotations click to browse term
  biological_process 19497
    biological regulation 13606
      regulation of biological process 12866
        regulation of multicellular organismal process 2968
          regulation of system process 667
            regulation of muscle system process 266
              regulation of muscle hypertrophy 76
                positive regulation of muscle hypertrophy 41
                  positive regulation of cardiac muscle hypertrophy + 40
                  positive regulation of skeletal muscle hypertrophy 2
                  positive regulation of smooth muscle hypertrophy 0
paths to the root