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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of muscle hypertrophy
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Accession:GO:0014741 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy.


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negative regulation of muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mstn myostatin IMP RGD PMID:16810717 RGD:2303557 NCBI chr 9:53,310,977...53,315,804
Ensembl chr 9:53,309,598...53,315,915
JBrowse link
negative regulation of cardiac muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap1 A-kinase anchoring protein 1 IMP RGD PMID:19358331 RGD:2312604 NCBI chr10:76,151,013...76,183,987
Ensembl chr10:76,151,038...76,166,276
JBrowse link
G Bmp10 bone morphogenetic protein 10 involved_in IEA
ISO
GO_REF:0000107
(MGI:3695247|PMID:16798733)
Ensembl
RGD
PMID:16798733 GO_REF:0000107 MGI:3695247 NCBI chr 4:119,224,906...119,230,534
Ensembl chr 4:119,225,040...119,230,728
JBrowse link
G Cav3 caveolin 3 acts_upstream_of_or_within
involved_in
ISO (PMID:12847114)
MGI:2180558 (MGI:3804582|PMID:18552160)
RGD PMID:12847114 PMID:18552160 MGI:3804582 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917
JBrowse link
G Fbxo32 F-box protein 32 involved_in IMP PMID:24117217 BHF-UCL PMID:24117217, PMID:24117217 RGD:11079185, RGD:11079185 NCBI chr 7:98,065,664...98,098,071
Ensembl chr 7:98,063,735...98,098,268
JBrowse link
G Gata5 GATA binding protein 5 involved_in ISO (MGI:5286818|PMID:21633169) RGD PMID:21633169 MGI:5286818 NCBI chr 3:175,701,278...175,709,465
Ensembl chr 3:175,701,280...175,709,465
JBrowse link
G Glrx3 glutaredoxin 3 involved_in ISO (MGI:4461873|PMID:18258855) RGD PMID:18258855 MGI:4461873 NCBI chr 1:209,768,696...209,799,912
Ensembl chr 1:209,768,696...209,799,903
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta acts_upstream_of_or_within ISO (MGI:2157270|PMID:11782539) RGD PMID:11782539 MGI:2157270 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 involved_in IGI
IMP
PMID:24657879 BHF-UCL PMID:24657879, PMID:24657879, PMID:24657879, PMID:24657879 RGD:11344938, RGD:11344938, RGD:11344938, RGD:11344938 NCBI chr17:20,183,440...20,365,219
Ensembl chr17:20,184,245...20,364,714
JBrowse link
G Mlip muscular LMNA-interacting protein acts_upstream_of_or_within
involved_in
ISS
ISO
GO_REF:0000024
(MGI:5581934|PMID:22343712)
UniProt
RGD
PMID:22343712 GO_REF:0000024 MGI:5581934 NCBI chr 8:84,409,957...84,634,637
Ensembl chr 8:84,434,784...84,632,817
JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G P2rx4 purinergic receptor P2X 4 involved_in ISO (PMID:15130891) RGD PMID:15130891 NCBI chr12:39,308,022...39,325,673
Ensembl chr12:39,308,025...39,325,673
JBrowse link
G Rgs2 regulator of G-protein signaling 2 involved_in ISO (MGI:3836877|PMID:19127022) RGD PMID:19127022 MGI:3836877 NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094
JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:3689643|PMID:16151019)
Ensembl
RGD
PMID:16151019 GO_REF:0000107 MGI:3689643 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P25119 (MGI:6158728|PMID:26491108)
Ensembl
RGD
PMID:26491108 GO_REF:0000107 MGI:6158728 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO UniProtKB:P25118 (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
G Trim63 tripartite motif containing 63 involved_in IMP PMID:24117217 BHF-UCL PMID:24117217, PMID:24117217 RGD:11079185, RGD:11079185 NCBI chr 5:152,533,362...152,547,138
Ensembl chr 5:152,533,349...152,547,179
JBrowse link
negative regulation of cardiac muscle hypertrophy in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISO (PMID:19287093)
(MGI:3848765|PMID:19287093)
RGD PMID:19287093 MGI:3848765 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 IDA RGD PMID:19204184 RGD:9685562 NCBI chr 5:167,951,564...167,966,011
Ensembl chr 5:167,952,728...167,966,009
JBrowse link
G Foxo1 forkhead box O1 involved_in IMP PMID:26436652 UniProt PMID:26436652, PMID:26436652 RGD:13210548, RGD:13210548 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
JBrowse link
G Lmna lamin A/C involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5700584|PMID:26436652)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:26436652 GO_REF:0000024 GO_REF:0000107 MGI:5700584 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G Mlip muscular LMNA-interacting protein involved_in ISO (MGI:5700584|PMID:26436652), (MGI:5908525|PMID:26359501) RGD PMID:26359501 PMID:26436652 MGI:5700584 MGI:5908525 NCBI chr 8:84,409,957...84,634,637
Ensembl chr 8:84,434,784...84,632,817
JBrowse link
G Smad3 SMAD family member 3 involved_in IGI PMID:27038547 BHF-UCL PMID:27038547, PMID:27038547 RGD:11535100, RGD:11535100 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
negative regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 IMP RGD PMID:21170593 RGD:6784534 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917
JBrowse link
G Ctdp1 CTD phosphatase subunit 1 IMP RGD PMID:22569295 RGD:9686371 NCBI chr18:76,922,913...76,985,095
Ensembl chr18:76,922,934...76,984,203
JBrowse link
G Foxp1 forkhead box P1 IMP RGD PMID:26333362 RGD:11561912 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IMP RGD PMID:24190878 RGD:10449133 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO (MGI:4829580|PMID:20516643) RGD PMID:20516643 MGI:4829580 NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203
JBrowse link
G Mir451a microRNA 451a IMP RGD PMID:25209900 RGD:11558015 NCBI chr10:65,291,204...65,291,275
Ensembl chr10:65,291,204...65,291,275
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 IMP RGD PMID:22082674 RGD:11533929 NCBI chr 1:162,768,156...162,883,356
Ensembl chr 1:162,768,156...162,883,355
JBrowse link
G Pi16 peptidase inhibitor 16 acts_upstream_of_or_within ISO (MGI:3810223|PMID:17909105) RGD PMID:17909105 MGI:3810223 NCBI chr20:6,923,176...6,932,786
Ensembl chr20:6,923,489...6,932,786
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha IMP RGD PMID:22198280 RGD:5687133 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Rgs2 regulator of G-protein signaling 2 IMP RGD PMID:16380388 RGD:13524577 NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094
JBrowse link
G Rgs4 regulator of G-protein signaling 4 IDA RGD PMID:9918533 RGD:7207376 NCBI chr13:88,054,817...88,061,108
Ensembl chr13:88,054,817...88,061,108
JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 IMP RGD PMID:25022898 RGD:13464131 NCBI chr11:45,477,053...45,511,409
Ensembl chr11:45,480,250...45,510,961
JBrowse link
G Yy1 YY1 transcription factor IMP RGD PMID:18632988 RGD:9588273 NCBI chr 6:132,702,443...132,726,848
Ensembl chr 6:132,702,448...132,727,046
JBrowse link
G Zfp418 zinc finger protein 418 acts_upstream_of_or_within ISO (MGI:5920524|PMID:29065170) RGD PMID:29065170 MGI:5920524 NCBI chr 1:69,615,413...69,629,997
Ensembl chr 1:69,615,434...69,629,913
JBrowse link
negative regulation of skeletal muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igfbp5 insulin-like growth factor binding protein 5 involved_in ISO (MGI:3039207|PMID:15010534) RGD PMID:15010534 MGI:3039207 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20082
    negative regulation of biological process 5713
      negative regulation of multicellular organismal process 1133
        negative regulation of muscle hypertrophy 35
          negative regulation of cardiac muscle hypertrophy + 33
          negative regulation of skeletal muscle hypertrophy 1
          negative regulation of smooth muscle hypertrophy 0
Path 2
Term Annotations click to browse term
  biological_process 20082
    biological regulation 13906
      regulation of biological process 13141
        regulation of multicellular organismal process 2932
          regulation of system process 660
            regulation of muscle system process 267
              regulation of muscle hypertrophy 76
                negative regulation of muscle hypertrophy 35
                  negative regulation of cardiac muscle hypertrophy + 33
                  negative regulation of skeletal muscle hypertrophy 1
                  negative regulation of smooth muscle hypertrophy 0
paths to the root