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ONTOLOGY REPORT - ANNOTATIONS


Term:skeletal muscle hypertrophy
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Accession:GO:0014734 term browser browse the term
Definition:The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils.


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skeletal muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor IMP RGD PMID:7957162 RGD:10043318 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Myoc myocilin involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:5320812|PMID:22371502)
Ensembl
UniProt
RGD
PMID:22371502 GO_REF:0000024 GO_REF:0000107 MGI:5320812 NCBI chr13:80,517,531...80,527,928
Ensembl chr13:80,517,536...80,527,928
JBrowse link
negative regulation of skeletal muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igfbp5 insulin-like growth factor binding protein 5 ISO (MGI:3039207|PMID:15010534) RGD PMID:15010534 MGI:3039207 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
positive regulation of skeletal muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:23470307 RGD:10041029 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Mymk myomaker, myoblast fusion factor ISO (MGI:6116777|PMID:28186492) RGD PMID:28186492 MGI:6116777 NCBI chr 3:5,608,243...5,617,689
Ensembl chr 3:5,608,243...5,617,225
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20078
    response to stimulus 10589
      muscle adaptation 140
        striated muscle adaptation 56
          skeletal muscle adaptation 31
            skeletal muscle hypertrophy 5
              negative regulation of skeletal muscle hypertrophy 1
              positive regulation of skeletal muscle hypertrophy 2
              regulation of skeletal muscle hypertrophy + 3
Path 2
Term Annotations click to browse term
  biological_process 20078
    multicellular organismal process 9072
      system process 3458
        muscle system process 461
          muscle adaptation 140
            striated muscle adaptation 56
              skeletal muscle adaptation 31
                skeletal muscle hypertrophy 5
                  negative regulation of skeletal muscle hypertrophy 1
                  positive regulation of skeletal muscle hypertrophy 2
                  regulation of skeletal muscle hypertrophy + 3
paths to the root