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ONTOLOGY REPORT - ANNOTATIONS

Term:twitch skeletal muscle contraction
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Accession:GO:0014721 term browser browse the term
Definition:A process in which force is generated within twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The twitch skeletal muscle responds to neurostimulations with a contraction followed by a relaxation.


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fast-twitch skeletal muscle fiber contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SYNM synemin acts_upstream_of_or_within ISO (MGI:5661117|PMID:25567810) MGI PMID:25567810 MGI:5661117 NCBI chr 1:137,855,644...137,883,914 JBrowse link
positive regulation of fast-twitch skeletal muscle fiber contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:5,860,386...5,873,779
Ensembl chr 2:5,860,391...5,874,124 		JBrowse link
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 3:18,545,064...18,568,312
Ensembl chr 3:18,545,071...18,568,310 		JBrowse link
G MYLK2 myosin light chain kinase 2 ISO RGD PMID:12748068 RGD:1580242 NCBI chr17:35,499,828...35,513,096
Ensembl chr17:35,499,887...35,513,093 		JBrowse link
regulation of slow-twitch skeletal muscle fiber contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC106505720 uncharacterized LOC106505720 involved_in IEA InterPro GO_REF:0000002 NCBI chr13:95,231,572...95,285,354 JBrowse link
G MYH7 myosin heavy chain 7 involved_in ISO (PMID:7883988) BHF-UCL PMID:7883988 NCBI chr 7:75,650,841...75,672,908
Ensembl chr 7:75,648,442...75,673,225 		JBrowse link
G STRIT1 small transmembrane regulator of ion transport 1 involved_in IEA InterPro GO_REF:0000002 Ensembl chr13:95,231,763...95,235,353 JBrowse link
slow-twitch skeletal muscle fiber contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MB myoglobin ISO RGD PMID:15981298 RGD:1582404
G TNNT1 troponin T1, slow skeletal type involved_in IBA
ISO		 (PMID:21873635) GO_Central
GO_Central
RGD		 PMID:15788488 PMID:21873635 RGD:1599482 NCBI chr 6:59,351,445...59,365,584
Ensembl chr 6:59,347,582...59,365,284 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17625
    multicellular organismal process 8693
      multicellular organismal movement 69
        musculoskeletal movement 68
          skeletal muscle contraction 51
            voluntary skeletal muscle contraction 9
              twitch skeletal muscle contraction 9
                fast-twitch skeletal muscle fiber contraction + 4
                regulation of twitch skeletal muscle contraction + 6
                slow-twitch skeletal muscle fiber contraction + 5
Path 2
Term Annotations click to browse term
  biological_process 17625
    multicellular organismal process 8693
      system process 3260
        muscle system process 462
          muscle contraction 328
            striated muscle contraction 185
              skeletal muscle contraction 51
                voluntary skeletal muscle contraction 9
                  twitch skeletal muscle contraction 9
                    fast-twitch skeletal muscle fiber contraction + 4
                    regulation of twitch skeletal muscle contraction + 6
                    slow-twitch skeletal muscle fiber contraction + 5
paths to the root