ONTOLOGY REPORT - ANNOTATIONS
Term: twitch skeletal muscle contraction
Accession: GO:0014721
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Definition: A process in which force is generated within twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The twitch skeletal muscle responds to neurostimulations with a contraction followed by a relaxation.
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Synm
synemin, intermediate filament protein
involved_in acts_upstream_of_or_within
IBA IMP
(MGI:6201960|PMID:21873635) (MGI:5661117|PMID:25567810)
GO_Central MGI
PMID:21873635 PMID:25567810
MGI:5661117 MGI:6201960
NCBI chr 7:67,379,909...67,409,490
Ensembl chr 7:67,379,908...67,409,490
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Actn3
actinin alpha 3
involved_in
IMP
(MGI:3778600|PMID:18178581)
UniProt
PMID:18178581
MGI:3778600
NCBI chr19:4,911,244...4,927,937
Ensembl chr19:4,911,244...4,927,937
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Atp2a1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr 7:126,045,032...126,062,245
Ensembl chr 7:126,045,030...126,062,280
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Mylk2
myosin, light polypeptide kinase 2, skeletal muscle
involved_in
ISO
RGD MGI
PMID:12748068
GO_REF:0000096 MGI:4417868 RGD:1580242
NCBI chr 2:152,753,265...152,764,985
Ensembl chr 2:152,753,272...152,764,988
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Myh7
myosin, heavy polypeptide 7, cardiac muscle, beta
involved_in
ISO
MGI
GO_REF:0000096 MGI:4834177
NCBI chr14:55,208,141...55,232,083
Ensembl chr14:55,208,141...55,232,083
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Strit1
small transmembrane regulator of ion transport 1
involved_in
IDA
(MGI:5751610|PMID:26816378)
UniProt
PMID:26816378
MGI:5751610
NCBI chr 3:63,388,516...63,391,327
Ensembl chr 3:63,388,533...63,391,300
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Mb
myoglobin
ISO
RGD
PMID:15981298
RGD:1582404
NCBI chr15:76,899,687...76,934,868
Ensembl chr15:76,899,687...76,934,870
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Tnnt1
troponin T1, skeletal, slow
involved_in
IBA ISO
(MGI:6201960|PMID:21873635)
GO_Central MGI RGD
PMID:15788488 PMID:21873635
GO_REF:0000096 MGI:4417868 MGI:6201960 RGD:1599482
NCBI chr 7:4,507,568...4,518,974
Ensembl chr 7:4,507,569...4,519,381
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