Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:twitch skeletal muscle contraction
go back to main search page
Accession:GO:0014721 term browser browse the term
Definition:A process in which force is generated within twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The twitch skeletal muscle responds to neurostimulations with a contraction followed by a relaxation.


show annotations for term's descendants           Sort by:
fast-twitch skeletal muscle fiber contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SYNM synemin involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 (PMID:21873635)
(MGI:5661117|PMID:25567810)		 GO_Central
Ensembl
GO_Central
MGI		 PMID:21873635 PMID:25567810 GO_REF:0000107 MGI:5661117 NCBI chr15:99,105,080...99,141,767
Ensembl chr15:99,098,217...99,135,593 		JBrowse link
positive regulation of fast-twitch skeletal muscle fiber contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in IEA
ISS		 Ensembl
Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:66,546,395...66,563,334
Ensembl chr11:66,546,395...66,563,334 		JBrowse link
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in IDA (PMID:12479237) UniProt
UniProt		 PMID:12479237 NCBI chr16:28,878,488...28,904,466
Ensembl chr16:28,878,405...28,904,466 		JBrowse link
G MYLK2 myosin light chain kinase 2 ISO RGD PMID:12748068 RGD:1580242 NCBI chr20:31,819,356...31,834,684
Ensembl chr20:31,819,308...31,834,689 		JBrowse link
regulation of slow-twitch skeletal muscle fiber contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYH7 myosin heavy chain 7 involved_in IMP (PMID:7883988) BHF-UCL
BHF-UCL		 PMID:7883988 NCBI chr14:23,412,740...23,435,660
Ensembl chr14:23,412,740...23,435,660 		JBrowse link
G STRIT1 small transmembrane regulator of ion transport 1 involved_in ISS
IEA		 UniProt
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000024 NCBI chr 3:155,290,227...155,293,683
Ensembl chr 3:155,290,227...155,293,683 		JBrowse link
slow-twitch skeletal muscle fiber contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MB myoglobin ISO RGD PMID:15981298 RGD:1582404 NCBI chr22:35,606,764...35,623,354
Ensembl chr22:35,606,764...35,637,951 		JBrowse link
G TNNT1 troponin T1, slow skeletal type involved_in IBA
IEA
ISO		 (PMID:21873635) GO_Central
Ensembl
GO_Central
RGD		 PMID:15788488 PMID:21873635 GO_REF:0000107 RGD:1599482 NCBI chr19:55,132,698...55,149,206
Ensembl chr19:55,132,698...55,149,206 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19815
    multicellular organismal process 8942
      multicellular organismal movement 72
        musculoskeletal movement 71
          skeletal muscle contraction 54
            voluntary skeletal muscle contraction 8
              twitch skeletal muscle contraction 8
                fast-twitch skeletal muscle fiber contraction + 4
                regulation of twitch skeletal muscle contraction + 5
                slow-twitch skeletal muscle fiber contraction + 4
Path 2
Term Annotations click to browse term
  biological_process 19815
    multicellular organismal process 8942
      system process 2652
        muscle system process 549
          muscle contraction 399
            striated muscle contraction 214
              skeletal muscle contraction 54
                voluntary skeletal muscle contraction 8
                  twitch skeletal muscle contraction 8
                    fast-twitch skeletal muscle fiber contraction + 4
                    regulation of twitch skeletal muscle contraction + 5
                    slow-twitch skeletal muscle fiber contraction + 4
paths to the root