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ONTOLOGY REPORT - ANNOTATIONS

Term:twitch skeletal muscle contraction
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Accession:GO:0014721 term browser browse the term
Definition:A process in which force is generated within twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The twitch skeletal muscle responds to neurostimulations with a contraction followed by a relaxation.


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fast-twitch skeletal muscle fiber contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SYNM synemin acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:5661117|PMID:25567810)
(PMID:21873635)		 MGI
GO_Central		 PMID:21873635 PMID:25567810 MGI:5661117 NCBI chr 3:41,595,218...41,623,475
Ensembl chr 3:41,594,580...41,623,627 		JBrowse link
positive regulation of fast-twitch skeletal muscle fiber contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:50,787,353...50,801,036
Ensembl chr18:50,787,353...50,801,197 		JBrowse link
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:18,384,981...18,400,038
Ensembl chr 6:18,385,007...18,400,036 		JBrowse link
G MYLK2 myosin light chain kinase 2 ISO RGD PMID:12748068 RGD:1580242 NCBI chr24:21,284,309...21,297,889
Ensembl chr24:21,284,352...21,309,363 		JBrowse link
regulation of slow-twitch skeletal muscle fiber contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYH6 myosin heavy chain 6 involved_in IEA Ensembl GO_REF:0000107
G MYH7 myosin heavy chain 7 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 8:3,660,155...3,677,650
Ensembl chr 8:3,629,585...3,792,725 		JBrowse link
G STRIT1 small transmembrane regulator of ion transport 1 involved_in IEA InterPro
InterPro		 GO_REF:0000002 NCBI chr23:49,131,218...49,134,728
Ensembl chr23:49,131,221...49,134,942 		JBrowse link
slow-twitch skeletal muscle fiber contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MB myoglobin ISO RGD PMID:15981298 RGD:1582404 NCBI chr10:28,573,819...28,583,526
Ensembl chr10:28,552,749...28,583,522 		JBrowse link
G TNNT1 troponin T1, slow skeletal type involved_in ISO
IBA		 (PMID:21873635) RGD
GO_Central		 PMID:15788488 PMID:21873635 RGD:1599482 NCBI chr 1:102,479,617...102,490,776
Ensembl chr 1:102,366,801...102,491,147 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17405
    multicellular organismal process 8176
      multicellular organismal movement 70
        musculoskeletal movement 69
          skeletal muscle contraction 51
            voluntary skeletal muscle contraction 9
              twitch skeletal muscle contraction 9
                fast-twitch skeletal muscle fiber contraction + 4
                regulation of twitch skeletal muscle contraction + 6
                slow-twitch skeletal muscle fiber contraction + 5
Path 2
Term Annotations click to browse term
  biological_process 17405
    multicellular organismal process 8176
      system process 2694
        muscle system process 459
          muscle contraction 328
            striated muscle contraction 186
              skeletal muscle contraction 51
                voluntary skeletal muscle contraction 9
                  twitch skeletal muscle contraction 9
                    fast-twitch skeletal muscle fiber contraction + 4
                    regulation of twitch skeletal muscle contraction + 6
                    slow-twitch skeletal muscle fiber contraction + 5
paths to the root