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ONTOLOGY REPORT - ANNOTATIONS

Term:response to isoquinoline alkaloid
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Accession:GO:0014072 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.


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cellular response to isoquinoline alkaloid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egr1 early growth response 1 IEP berberine RGD PMID:16448624 RGD:5131909 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Mecp2 methyl CpG binding protein 2 IDA bicuculline RGD PMID:22262897 RGD:12790719 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689 		JBrowse link
cellular response to morphine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy8 adenylate cyclase 8 involved_in IEA
ISO
ISS
IDA		 GO_REF:0000107
(PMID:18222416)
GO_REF:0000024
PMID:16186630		 Ensembl
RGD
UniProt		 PMID:18222416 PMID:16186630 GO_REF:0000024 GO_REF:0000107, RGD:13825193 NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911 		JBrowse link
G Aif1 allograft inflammatory factor 1 IEP morphine RGD PMID:19176808 RGD:2313012 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Atg7 autophagy related 7 IEP RGD PMID:23800874 RGD:11557986 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEP RGD PMID:20578038 RGD:4889899 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 IEP RGD PMID:18178009 RGD:6483056 NCBI chr11:34,061,702...34,308,758
Ensembl chr11:34,061,708...34,308,758 		JBrowse link
G Oprm1 opioid receptor, mu 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B involved_in ISS
ISO		 GO_REF:0000024
(PMID:18439408)		 UniProt
RGD		 PMID:18439408 GO_REF:0000024 NCBI chr10:79,938,055...79,954,085
Ensembl chr10:79,938,066...79,954,083 		JBrowse link
G Ptk2 protein tyrosine kinase 2 IEP RGD PMID:26821693 RGD:401959306 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G RT1-Bb RT1 class II, locus Bb IEP RGD PMID:14742686 RGD:7488923 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
response to codeine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A IEP RGD PMID:24914722 RGD:11041146 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
response to morphine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1b adrenoceptor alpha 1B acts_upstream_of_or_within ISO MGI:2148638 (PMID:11923452) RGD PMID:11923452 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919 		JBrowse link
G Adra2a adrenoceptor alpha 2A IEP RGD PMID:9105684 RGD:401976538 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Ago2 argonaute RISC catalytic component 2 IEP RGD PMID:23927484 RGD:401900655 NCBI chr 7:105,018,202...105,105,118
Ensembl chr 7:105,029,120...105,104,974 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein IEP RGD PMID:21549764 PMID:30550948 RGD:401851922, RGD:401959617 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Arrb1 arrestin, beta 1 IEP RGD PMID:12614678 RGD:401938620 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Arrb2 arrestin, beta 2 IEP RGD PMID:12614678 RGD:401938620 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Bdnf brain-derived neurotrophic factor IEP RGD PMID:30550948 RGD:401959617 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Cartpt CART prepropeptide IEP RGD PMID:32198124 RGD:407571681 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 IEP RGD PMID:19324071 RGD:401901600 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Drd2 dopamine receptor D2 acts_upstream_of_or_within ISO MGI:1857875|MGI:2387895|MGI:2388386|MGI:2656648 (PMID:11264672), (PMID:11567069), (PMID:12182883), (PMID:9252189) RGD PMID:9252189 PMID:11264672 PMID:11567069 PMID:12182883 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 acts_upstream_of_or_within ISO MGI:1857159 (PMID:12574430) RGD PMID:12574430 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Egr1 early growth response 1 IEP RGD PMID:30550948 RGD:401959617 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit IEP RGD PMID:23185589 PMID:31442272 PMID:20438612 RGD:401851068, RGD:401851072, RGD:401900159 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Gad1 glutamate decarboxylase 1 IEP RGD PMID:15673448 RGD:401900167 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 IEP
IMP		 RGD PMID:25716866 PMID:22072679 PMID:32717192 PMID:24201449 RGD:401976466, RGD:405101690, RGD:405100728, RGD:405096668 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 acts_upstream_of_or_within ISO MGI:1928270 (PMID:18423864) RGD PMID:18423864 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A IEP RGD PMID:24055683 RGD:405866344 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 IEP RGD PMID:15673448 RGD:401900167 NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 IMP RGD PMID:16766046 RGD:405096662 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IEP RGD PMID:32198124 RGD:407571681 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B acts_upstream_of_or_within ISO MGI:3799291 (PMID:18496528) RGD PMID:18496528 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775 		JBrowse link
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:16102737)		 Ensembl
RGD		 PMID:16102737 GO_REF:0000107 NCBI chr15:41,204,659...41,263,924
Ensembl chr15:41,204,200...41,263,924 		JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:16102737)		 Ensembl
RGD		 PMID:16102737 GO_REF:0000107 NCBI chr 1:77,690,203...77,714,507
Ensembl chr 1:77,690,208...77,714,456 		JBrowse link
G Prkce protein kinase C, epsilon involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2152043 (PMID:16899053)		 Ensembl
RGD		 PMID:16899053 GO_REF:0000107 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719 		JBrowse link
G Prkcg protein kinase C, gamma involved_in ISS
ISO		 GO_REF:0000024
(PMID:11246146)		 UniProt
RGD		 PMID:11246146 GO_REF:0000024 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 involved_in ISO MGI:2655190 (PMID:28049029) RGD PMID:28049029 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    response to stimulus 10795
      response to chemical 5901
        response to organic cyclic compound 1450
          response to isoquinoline alkaloid 37
            cellular response to isoquinoline alkaloid + 11
            response to codeine + 1
            response to dextromethorphan + 0
            response to morphine + 35
Path 2
Term Annotations click to browse term
  biological_process 20076
    response to stimulus 10795
      response to chemical 5901
        response to nitrogen compound 1550
          response to alkaloid 193
            response to isoquinoline alkaloid 37
              cellular response to isoquinoline alkaloid + 11
              response to codeine + 1
              response to dextromethorphan + 0
              response to morphine + 35
paths to the root