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ONTOLOGY REPORT - ANNOTATIONS

Term:glutamate secretion
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Accession:GO:0014047 term browser browse the term
Definition:The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system.

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glutamate secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apba1 amyloid beta precursor protein binding family A member 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936503:5,699,580...5,770,920
Ensembl chrNW_004936503:5,699,558...5,771,030 		JBrowse link
G Bdnf brain derived neurotrophic factor acts_upstream_of_or_within ISO (PMID:16819522) MGI PMID:16819522 NCBI chrNW_004936540:5,530,081...5,582,765
Ensembl chrNW_004936540:5,529,942...5,585,014 		JBrowse link
G Best1 bestrophin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936581:1,120,681...1,132,226
Ensembl chrNW_004936581:1,120,474...1,132,230 		JBrowse link
G Gipc1 GIPC PDZ domain containing family member 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936659:3,019,829...3,030,280
Ensembl chrNW_004936659:3,012,012...3,026,883 		JBrowse link
G Gja1 gap junction protein alpha 1 involved_in ISO (PMID:26200696) ARUK-UCL PMID:26200696 NCBI chrNW_004936658:3,920,043...3,932,987
Ensembl chrNW_004936658:3,920,043...3,932,987 		JBrowse link
G Grm2 glutamate metabotropic receptor 2 involved_in ISO PMID:15993439 UniProt PMID:15993439 RGD:8553886 NCBI chrNW_004936529:3,042,220...3,053,670
Ensembl chrNW_004936529:3,042,248...3,053,673 		JBrowse link
G Kcnk1 potassium two pore domain channel subfamily K member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936484:18,186,184...18,221,304
Ensembl chrNW_004936484:18,186,144...18,220,938 		JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936628:3,155,261...3,284,375
Ensembl chrNW_004936628:3,154,109...3,345,660 		JBrowse link
G Myo6 myosin VI acts_upstream_of_or_within ISO (PMID:16819522) MGI PMID:16819522 NCBI chrNW_004936788:1,125,332...1,264,372
Ensembl chrNW_004936788:1,174,544...1,262,746 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936680:267,850...621,467
Ensembl chrNW_004936680:267,596...615,928 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chrNW_004936558:3,106,819...3,149,689
Ensembl chrNW_004936558:3,108,283...3,149,765 		JBrowse link
G Pianp PILR alpha associated neural protein acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936709:1,102,730...1,111,143
Ensembl chrNW_004936709:1,102,477...1,110,420 		JBrowse link
G Rgs19 regulator of G protein signaling 19 acts_upstream_of_or_within ISO (PMID:16819522) MGI PMID:16819522 NCBI chrNW_004936514:11,251,293...11,256,461
Ensembl chrNW_004936514:11,251,202...11,255,994 		JBrowse link
G Trpv1 transient receptor potential cation channel subfamily V member 1 ISO RGD PMID:18480286 RGD:2317101 NCBI chrNW_004936677:277,304...326,907
Ensembl chrNW_004936677:276,994...327,025 		JBrowse link
glutamate secretion, neurotransmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936528:1,608,782...1,682,873
Ensembl chrNW_004936528:1,608,757...1,682,975 		JBrowse link
G Kcnj8 potassium inwardly rectifying channel subfamily J member 8 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936548:5,125,583...5,132,490
Ensembl chrNW_004936548:5,125,555...5,133,078 		JBrowse link
G Nf1 neurofibromin 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936538:3,394,623...3,596,025
Ensembl chrNW_004936538:3,398,222...3,595,261 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 acts_upstream_of_or_within ISO (PMID:25242307) MGI PMID:25242307 NCBI chrNW_004936498:6,001,126...6,135,663
Ensembl chrNW_004936498:6,001,014...6,086,614 		JBrowse link
negative regulation of glutamate secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor ISO K+-evoked glutamate release RGD PMID:16481441 RGD:1625231 NCBI chrNW_004936567:1,430,128...1,508,626
Ensembl chrNW_004936567:1,429,817...1,462,532 		JBrowse link
G Grm7 glutamate metabotropic receptor 7 ISO RGD PMID:11825890 PMID:12692128 RGD:2289010 RGD:728749 NCBI chrNW_004936602:5,111,406...5,488,506
Ensembl chrNW_004936602:5,110,995...5,488,555 		JBrowse link
G Hrh3 histamine receptor H3 ISO RGD PMID:17027043 RGD:1626422 NCBI chrNW_004936514:9,862,104...9,865,614
Ensembl chrNW_004936514:9,862,523...9,873,159 		JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 ISO RGD PMID:16987217 RGD:2317005 NCBI chrNW_004936474:5,848,719...5,858,520
Ensembl chrNW_004936474:5,848,707...5,859,749 		JBrowse link
G Il1b interleukin 1 beta ISO RGD PMID:12667655 RGD:1626684 NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO RGD PMID:12667655 RGD:1626684 NCBI chrNW_004936783:1,447,158...1,466,331
Ensembl chrNW_004936783:1,447,106...1,466,340 		JBrowse link
G Npy5r neuropeptide Y receptor Y5 ISO RGD PMID:12623227 RGD:1625502 NCBI chrNW_004936555:2,248,699...2,252,637
Ensembl chrNW_004936555:2,248,699...2,252,637 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 ISO RGD PMID:10081919 RGD:7777119 NCBI chrNW_004936787:330,390...1,491,994
Ensembl chrNW_004936787:332,342...1,491,285 		JBrowse link
G Trh thyrotropin releasing hormone involved_in ISO
IEA 		RGD
TreeGrafter		 PMID:16055093 GO_REF:0000118 RGD:1600422 NCBI chrNW_004936602:623,542...626,337
Ensembl chrNW_004936602:623,535...626,445 		JBrowse link
positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dtnbp1 dystrobrevin binding protein 1 ISO RGD PMID:15345706 RGD:11251758 NCBI chrNW_004936552:1,787,687...1,926,516 JBrowse link
G Rab3gap1 RAB3 GTPase activating protein catalytic subunit 1 involved_in ISO (PMID:16782817) ParkinsonsUK-UCL PMID:16782817 NCBI chrNW_004936469:40,642,240...40,727,831
Ensembl chrNW_004936469:40,641,928...40,727,837 		JBrowse link
positive regulation of glutamate secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor ISO K+-evoked glutamate release RGD PMID:16481441 RGD:1625231 NCBI chrNW_004936619:597,970...618,564
Ensembl chrNW_004936619:608,441...616,779 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A ISO RGD PMID:17877638 RGD:2300342 NCBI chrNW_004936545:1,788,995...1,795,842
Ensembl chrNW_004936545:1,786,571...1,794,709 		JBrowse link
G Avpr1b arginine vasopressin receptor 1B ISO RGD PMID:17877638 RGD:2300342 NCBI chrNW_004936557:6,415,544...6,423,863
Ensembl chrNW_004936557:6,415,547...6,424,711 		JBrowse link
G Cck cholecystokinin involved_in ISO PMID:20392936 CACAO PMID:20392936 RGD:10047227 NCBI chrNW_004936695:2,776,705...2,782,280
Ensembl chrNW_004936695:2,776,831...2,782,061 		JBrowse link
G Dpysl2 dihydropyrimidinase like 2 ISO RGD PMID:19755421 RGD:2316240 NCBI chrNW_004936757:311,317...422,870
Ensembl chrNW_004936757:309,022...422,955 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 ISO RGD PMID:18765663 RGD:7241136 NCBI chrNW_004936723:1,108,105...1,137,602
Ensembl chrNW_004936723:1,107,995...1,137,178 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B involved_in ISO PMID:16407536 UniProt PMID:16407536 RGD:8553534 NCBI chrNW_004936587:3,406,055...3,806,956
Ensembl chrNW_004936587:3,405,698...3,804,664 		JBrowse link
G Kmo kynurenine 3-monooxygenase ISO RGD PMID:15829251 RGD:13513901 NCBI chrNW_004936526:8,877,085...8,928,280
Ensembl chrNW_004936526:8,877,434...8,919,548 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3 group C member 1 ISO RGD PMID:19484722 RGD:4892315 NCBI chrNW_004936504:10,960,069...11,056,834
Ensembl chrNW_004936504:10,959,192...11,056,856 		JBrowse link
G Ntsr1 neurotensin receptor 1 ISO RGD PMID:18063561 RGD:9743970 NCBI chrNW_004936514:10,240,990...10,272,859
Ensembl chrNW_004936514:10,241,020...10,272,816 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936558:3,106,819...3,149,689
Ensembl chrNW_004936558:3,108,283...3,149,765 		JBrowse link
G Syt4 synaptotagmin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936517:3,035,840...3,044,065
Ensembl chrNW_004936517:3,035,521...3,047,964 		JBrowse link
positive regulation of glutamate secretion, neurotransmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kmo kynurenine 3-monooxygenase ISO RGD PMID:15829251 RGD:13513901 NCBI chrNW_004936526:8,877,085...8,928,280
Ensembl chrNW_004936526:8,877,434...8,919,548 		JBrowse link
G Stxbp1 syntaxin binding protein 1 ISO RGD PMID:16951547 RGD:12904030 NCBI chrNW_004936487:15,300,758...15,367,475
Ensembl chrNW_004936487:15,300,952...15,365,713 		JBrowse link
regulation of glutamate secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 ISO RGD PMID:15561437 RGD:2315491 NCBI chrNW_004936723:1,108,105...1,137,602
Ensembl chrNW_004936723:1,107,995...1,137,178 		JBrowse link
G Grm2 glutamate metabotropic receptor 2 ISO RGD PMID:28700935 PMID:30283001 RGD:38501063 RGD:38501064 NCBI chrNW_004936529:3,042,220...3,053,670
Ensembl chrNW_004936529:3,042,248...3,053,673 		JBrowse link
G Snca synuclein alpha acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936685:2,077,017...2,175,298
Ensembl chrNW_004936685:2,076,651...2,175,338 		JBrowse link
regulation of glutamate secretion, neurotransmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc38a2 solute carrier family 38 member 2 involved_in ISO PMID:18832333 UniProt PMID:18832333 RGD:152995567 NCBI chrNW_004936512:4,543,845...4,557,118
Ensembl chrNW_004936512:4,543,820...4,557,142 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17413
    cellular process 17012
      export from cell 1014
        secretion by cell 944
          glutamate secretion 43
            glutamate secretion, neurotransmission + 9
            negative regulation of glutamate secretion + 9
            positive regulation of glutamate secretion + 15
            regulation of glutamate secretion + 27
Path 2
Term Annotations click to browse term
  biological_process 17413
    localization 5152
      establishment of localization 4511
        transport 4201
          organic anion transport 445
            carboxylic acid transport 346
              dicarboxylic acid transport 110
                glutamate secretion 43
                  glutamate secretion, neurotransmission + 9
                  negative regulation of glutamate secretion + 9
                  positive regulation of glutamate secretion + 15
                  regulation of glutamate secretion + 27
paths to the root