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ONTOLOGY REPORT - ANNOTATIONS


Term:dopamine secretion
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Accession:GO:0014046 term browser browse the term
Definition:The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone.


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negative regulation of dopamine secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase IEA Ensembl GO_REF:0000107 NCBI chr16:8,674,617...8,784,575
Ensembl chr16:8,674,596...8,784,575
JBrowse link
G C5 complement C5 ISO RGD PMID:18648551 RGD:5130170 NCBI chr 9:120,952,335...121,074,865
Ensembl chr 9:120,952,335...121,050,275
Ensembl chr 9:120,952,335...121,050,275
JBrowse link
G CNR1 cannabinoid receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,359
JBrowse link
G DRD2 dopamine receptor D2 IEA Ensembl GO_REF:0000107 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 ISO RGD PMID:21325440 RGD:9685453 NCBI chr10:95,710,901...95,877,266
Ensembl chr10:95,711,779...95,877,266
JBrowse link
G GABBR1 gamma-aminobutyric acid type B receptor subunit 1 ISO RGD PMID:12872287 RGD:2315496 NCBI chr 6:29,602,230...29,633,183
Ensembl chr 6:29,555,629...29,633,976
JBrowse link
G SYT11 synaptotagmin 11 ISS UniProt GO_REF:0000024 NCBI chr 1:155,859,502...155,885,199
Ensembl chr 1:155,859,567...155,885,199
JBrowse link
positive regulation of dopamine secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISS UniProtKB GO_REF:0000024 NCBI chr 1:154,567,778...154,584,708
Ensembl chr 1:154,567,778...154,580,013
JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 IEA Ensembl GO_REF:0000107 NCBI chr10:44,292,088...44,385,097
Ensembl chr10:44,370,165...44,386,493
JBrowse link
G GDNF glial cell derived neurotrophic factor TAS (PMID:12358785) BHF-UCL PMID:12358785 NCBI chr 5:37,812,677...37,840,044
Ensembl chr 5:37,812,677...37,840,041
JBrowse link
G HTR6 5-hydroxytryptamine receptor 6 ISO RGD PMID:16987217 RGD:2317005 NCBI chr 1:19,664,875...19,680,966
Ensembl chr 1:19,664,875...19,680,966
JBrowse link
G NPY2R neuropeptide Y receptor Y2 IEA Ensembl GO_REF:0000107 NCBI chr 4:155,173,723...155,217,076
Ensembl chr 4:155,208,636...155,217,078
JBrowse link
G OPRK1 opioid receptor kappa 1 IEA Ensembl GO_REF:0000107 NCBI chr 8:53,225,724...53,251,637
Ensembl chr 8:53,225,724...53,251,637
Ensembl chr 8:53,225,724...53,251,637
JBrowse link
G PCP4 Purkinje cell protein 4 ISO RGD PMID:21671256 RGD:9850149 NCBI chr21:39,867,438...39,929,392
Ensembl chr21:39,867,438...39,929,397
JBrowse link
G PINK1 PTEN induced kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511
JBrowse link
G RTN4 reticulon 4 ISO RGD PMID:19112410 RGD:2314933 NCBI chr 2:54,972,189...55,137,831
Ensembl chr 2:54,972,187...55,112,621
JBrowse link
G SLC18A1 solute carrier family 18 member A1 ISO RGD PMID:17244889 RGD:5131195 NCBI chr 8:20,144,855...20,183,139
Ensembl chr 8:20,144,855...20,183,206
JBrowse link
G SYT1 synaptotagmin 1 IEA Ensembl GO_REF:0000107 NCBI chr12:78,863,982...79,452,008
Ensembl chr12:78,863,993...79,452,008
JBrowse link
regulation of dopamine secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISS UniProtKB GO_REF:0000024 NCBI chr20:63,343,223...63,375,471
Ensembl chr20:63,343,223...63,378,401
JBrowse link
G CHRNA6 cholinergic receptor nicotinic alpha 6 subunit IEA Ensembl GO_REF:0000107 NCBI chr 8:42,752,620...42,768,786
Ensembl chr 8:42,752,620...42,796,392
JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISS UniProtKB GO_REF:0000024 NCBI chr 1:154,567,778...154,584,708
Ensembl chr 1:154,567,778...154,580,013
JBrowse link
G DRD2 dopamine receptor D2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G DRD3 dopamine receptor D3 ISS
IBA
(PMID:21873635) BHF-UCL
GO_Central
PMID:21873635 GO_REF:0000024 NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
JBrowse link
G DTNBP1 dystrobrevin binding protein 1 ISS UniProtKB GO_REF:0000024 NCBI chr 6:15,522,803...15,663,058
Ensembl chr 6:15,522,801...15,663,058
Ensembl chr 6:15,522,801...15,663,058
JBrowse link
G FGF20 fibroblast growth factor 20 TAS (PMID:16988046) ParkinsonsUK-UCL PMID:16988046 NCBI chr 8:16,992,181...17,002,345
Ensembl chr 8:16,992,181...17,002,345
JBrowse link
G GRM2 glutamate metabotropic receptor 2 ISO RGD PMID:30283001 RGD:38501063 NCBI chr 3:51,707,068...51,718,616
Ensembl chr 3:51,707,068...51,718,613
JBrowse link
G HTR1B 5-hydroxytryptamine receptor 1B IEA Ensembl GO_REF:0000107 NCBI chr 6:77,460,924...77,463,491
Ensembl chr 6:77,461,753...77,463,773
Ensembl chr 6:77,461,753...77,463,773
JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A IEA Ensembl GO_REF:0000107 NCBI chr13:46,831,546...46,898,082
Ensembl chr13:46,831,550...46,897,076
JBrowse link
G KCNA2 potassium voltage-gated channel subfamily A member 2 ISS UniProtKB GO_REF:0000024 NCBI chr 1:110,593,580...110,631,536
Ensembl chr 1:110,519,837...110,631,474
JBrowse link
G PRKCB protein kinase C beta ISO RGD PMID:15647254 RGD:1625522 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase TAS (PMID:21563316) ParkinsonsUK-UCL PMID:21563316 NCBI chr 6:161,347,417...162,727,802
Ensembl chr 6:161,347,417...162,727,771
Ensembl chr 6:161,347,417...162,727,771
JBrowse link
G RAB3A RAB3A, member RAS oncogene family IEA Ensembl GO_REF:0000107 NCBI chr19:18,196,784...18,204,042
Ensembl chr19:18,196,784...18,204,042
JBrowse link
G SNCA synuclein alpha IEA
TAS
(PMID:21320589) InterPro
UniProtKB
PMID:21320589 GO_REF:0000002 NCBI chr 4:89,724,099...89,838,324
Ensembl chr 4:89,700,345...89,838,315
Ensembl chr 4:89,700,345...89,838,315
JBrowse link
G SNCG synuclein gamma IEA Ensembl GO_REF:0000107 NCBI chr10:86,955,759...86,963,260
Ensembl chr10:86,958,599...86,963,258
JBrowse link
G SYT1 synaptotagmin 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:78,863,982...79,452,008
Ensembl chr12:78,863,993...79,452,008
JBrowse link
G SYT10 synaptotagmin 10 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:33,374,238...33,439,819
Ensembl chr12:33,374,238...33,439,819
JBrowse link
G SYT11 synaptotagmin 11 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:155,859,502...155,885,199
Ensembl chr 1:155,859,567...155,885,199
JBrowse link
G SYT12 synaptotagmin 12 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:67,006,773...67,050,863
Ensembl chr11:67,006,778...67,050,863
JBrowse link
G SYT13 synaptotagmin 13 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:45,240,302...45,286,341
Ensembl chr11:45,240,302...45,286,341
JBrowse link
G SYT15 synaptotagmin 15 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:47,744,717...47,765,208
Ensembl chr10:47,749,758...47,763,592
Ensembl chr10:47,749,758...47,763,592
Ensembl chr10:47,749,758...47,763,592
JBrowse link
G SYT15 synaptotagmin 15 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:46,578,018...46,595,170
Ensembl chr10:46,578,217...46,594,173
JBrowse link
G SYT17 synaptotagmin 17 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:19,167,834...19,268,334
Ensembl chr16:19,167,971...19,268,332
JBrowse link
G SYT2 synaptotagmin 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:202,590,596...202,710,454
Ensembl chr 1:202,590,596...202,710,454
JBrowse link
G SYT3 synaptotagmin 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr19:50,621,977...50,639,881
Ensembl chr19:50,621,307...50,639,881
JBrowse link
G SYT4 synaptotagmin 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr18:43,267,892...43,277,490
Ensembl chr18:43,267,892...43,277,535
JBrowse link
G SYT5 synaptotagmin 5 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr19:55,171,196...55,180,441
Ensembl chr19:55,171,196...55,180,289
JBrowse link
G SYT6 synaptotagmin 6 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:114,089,292...114,153,869
Ensembl chr 1:114,089,291...114,153,880
Ensembl chr 1:114,089,291...114,153,880
JBrowse link
G SYT7 synaptotagmin 7 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:61,513,714...61,588,404
Ensembl chr11:61,513,714...61,581,148
Ensembl chr11:61,513,714...61,581,148
JBrowse link
G SYT8 synaptotagmin 8 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:1,827,484...1,837,521
Ensembl chr11:1,828,307...1,837,521
JBrowse link
G SYT9 synaptotagmin 9 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:7,238,784...7,470,032
Ensembl chr11:7,238,778...7,469,043
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18670
    signaling 7207
      cell-cell signaling 2063
        signal release 647
          dopamine secretion 46
            axonal dopamine secretion + 0
            negative regulation of dopamine secretion 7
            positive regulation of dopamine secretion 11
            regulation of dopamine secretion + 46
            somato-dendritic dopamine secretion 0
Path 2
Term Annotations click to browse term
  biological_process 18670
    localization 7208
      establishment of localization 5657
        transport 5515
          organic substance transport 2963
            monoamine transport 114
              catecholamine transport 97
                dopamine transport 62
                  dopamine secretion 46
                    axonal dopamine secretion + 0
                    negative regulation of dopamine secretion 7
                    positive regulation of dopamine secretion 11
                    regulation of dopamine secretion + 46
                    somato-dendritic dopamine secretion 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.