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ONTOLOGY REPORT - ANNOTATIONS


Term:dopamine secretion
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Accession:GO:0014046 term browser browse the term
Definition:The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone.


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negative regulation of dopamine secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase ISO RGD PMID:590329 RGD:10047092 NCBI chr16:7,609,282...7,718,049
Ensembl chr16:8,888,178...8,958,420
JBrowse link
G C5 complement C5 ISO RGD PMID:18648551 RGD:5130170 NCBI chr 9:92,069,574...92,202,513
Ensembl chr 9:120,426,354...120,523,856
JBrowse link
G CNR1 cannabinoid receptor 1 ISO RGD PMID:19187091 RGD:2314679 NCBI chr 6:86,017,141...86,044,889 JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:16490190 RGD:1625068 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935
JBrowse link
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 ISO RGD PMID:21325440 RGD:9685453 NCBI chr10:92,365,267...92,511,852
Ensembl chr10:95,828,094...95,983,257
JBrowse link
G GABBR1 gamma-aminobutyric acid type B receptor subunit 1 ISO RGD PMID:12872287 RGD:2315496 NCBI chr 6:29,405,026...29,437,108
Ensembl chr 6:30,065,119...30,095,304
JBrowse link
G SYT11 synaptotagmin 11 ISO (MGI:MGI:6114813|PMID:29311685) UniProt PMID:29311685 MGI:MGI:6114813, RGD:14929208 NCBI chr 1:131,193,999...131,218,752
Ensembl chr 1:135,026,032...135,046,943
JBrowse link
positive regulation of dopamine secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO (MGI:MGI:1194464|PMID:9428762) MGI PMID:9428762 MGI:MGI:1194464 NCBI chr 1:129,922,740...129,931,582
Ensembl chr 1:133,535,023...133,547,361
JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 ISO RGD PMID:18671738 RGD:2306573 NCBI chr10:41,296,975...41,384,864 JBrowse link
G HTR6 5-hydroxytryptamine receptor 6 ISO RGD PMID:16987217 RGD:2317005 NCBI chr 1:18,619,683...18,635,822
Ensembl chr 1:19,662,978...19,678,680
JBrowse link
G NPY2R neuropeptide Y receptor Y2 ISO RGD PMID:17382974 RGD:1642505 NCBI chr 4:147,542,551...147,586,397
Ensembl chr 4:159,401,080...159,402,231
JBrowse link
G OPRK1 opioid receptor kappa 1 ISO RGD PMID:17568430 RGD:9831445 NCBI chr 8:49,650,844...49,677,494
Ensembl chr 8:47,029,313...47,056,577
JBrowse link
G PCP4 Purkinje cell protein 4 ISO RGD PMID:21671256 RGD:9850149 NCBI chr21:26,069,039...26,284,247
Ensembl chr21:39,587,400...39,618,734
JBrowse link
G PINK1 PTEN induced kinase 1 ISO (MGI:MGI:3715376|PMID:17563363) MGI PMID:17563363 MGI:MGI:3715376 NCBI chr 1:19,583,330...19,601,248
Ensembl chr 1:20,627,693...20,645,560
JBrowse link
G RTN4 reticulon 4 ISO RGD PMID:19112410 RGD:2314933 NCBI chr2A:55,129,272...55,207,031 JBrowse link
G SLC18A1 solute carrier family 18 member A1 ISO RGD PMID:17244889 RGD:5131195 NCBI chr 8:19,369,843...19,408,412
Ensembl chr 8:16,318,744...16,353,708
JBrowse link
G SYT1 synaptotagmin 1 ISO PMID:28370453 CACAO PMID:28370453 RGD:15023476 NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923
JBrowse link
regulation of dopamine secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO (MGI:MGI:2673776|PMID:12944511) MGI PMID:12944511 MGI:MGI:2673776 NCBI chr20:59,730,759...59,748,678
Ensembl chr20:61,270,631...61,283,005
JBrowse link
G CHRNA6 cholinergic receptor nicotinic alpha 6 subunit ISO (MGI:MGI:2673776|PMID:12944511) MGI PMID:12944511 MGI:MGI:2673776 NCBI chr 8:42,000,748...42,016,913
Ensembl chr 8:39,444,447...39,460,569
JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO (MGI:MGI:2673776|PMID:12944511) MGI PMID:12944511 MGI:MGI:2673776 NCBI chr 1:129,922,740...129,931,582
Ensembl chr 1:133,535,023...133,547,361
JBrowse link
G DRD2 dopamine receptor D2 ISO (MGI:MGI:3655899|PMID:11943831) MGI PMID:11943831 MGI:MGI:3655899 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935
JBrowse link
G DRD3 dopamine receptor D3 ISO (MGI:MGI:1202050|PMID:9482807)
(MGI:MGI:3698022|PMID:12044470)
MGI
RGD
PMID:9482807, PMID:12044470, PMID:16490190 MGI:MGI:1202050, MGI:MGI:3698022, RGD:1625068 NCBI chr 3:111,265,834...111,317,176
Ensembl chr 3:118,187,636...118,237,403
JBrowse link
G DTNBP1 dystrobrevin binding protein 1 ISO (MGI:MGI:4398782|PMID:19887632) UniProtKB PMID:19887632 MGI:MGI:4398782 NCBI chr 6:15,377,263...15,523,317
Ensembl chr 6:15,741,698...15,887,256
JBrowse link
G GRM2 glutamate metabotropic receptor 2 ISO RGD PMID:30283001 RGD:38501063 NCBI chr 3:51,639,792...51,652,779
Ensembl chr 3:52,873,144...52,884,395
JBrowse link
G HTR1B 5-hydroxytryptamine receptor 1B ISO RGD PMID:16885935 RGD:1626459 NCBI chr 6:75,309,078...75,313,747
Ensembl chr 6:78,596,408...78,597,580
JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A ISO RGD PMID:15999145 RGD:1624397 NCBI chr13:27,976,415...28,042,941
Ensembl chr13:46,694,273...46,759,826
JBrowse link
G KCNA2 potassium voltage-gated channel subfamily A member 2 ISO (MGI:MGI:4947004|PMID:21233214) UniProtKB PMID:21233214 MGI:MGI:4947004 NCBI chr 1:113,187,158...113,256,260
Ensembl chr 1:127,090,829...127,092,328
JBrowse link
G PRKCB protein kinase C beta ISO RGD PMID:15647254 RGD:1625522 NCBI chr16:13,888,936...14,268,759
Ensembl chr16:24,091,289...24,466,203
JBrowse link
G RAB3A RAB3A, member RAS oncogene family ISO PMID:28370453 CACAO PMID:28370453 RGD:15023476 NCBI chr19:17,672,661...17,679,541
Ensembl chr19:18,649,166...18,656,768
JBrowse link
G SNCA synuclein alpha ISO (MGI:MGI:3777215|PMID:18333965) MGI PMID:18333965 MGI:MGI:3777215 NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600
JBrowse link
G SNCG synuclein gamma ISO (MGI:MGI:3777215|PMID:18333965) MGI PMID:18333965 MGI:MGI:3777215 NCBI chr10:83,383,566...83,391,064 JBrowse link
G SYT1 synaptotagmin 1 ISO (MGI:MGI:5795818|PMID:21576241) ParkinsonsUK-UCL PMID:21576241 MGI:MGI:5795818 NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923
JBrowse link
G SYT4 synaptotagmin 4 ISO (MGI:MGI:5795818|PMID:21576241) ParkinsonsUK-UCL PMID:21576241 MGI:MGI:5795818 NCBI chr18:36,540,756...36,550,439
Ensembl chr18:40,089,938...40,099,721
JBrowse link
G SYT7 synaptotagmin 7 ISO (MGI:MGI:5795818|PMID:21576241) ParkinsonsUK-UCL PMID:21576241 MGI:MGI:5795818 NCBI chr11:56,814,694...56,880,439 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12561
    signaling 4289
      cell-cell signaling 1368
        signal release 561
          dopamine secretion 31
            axonal dopamine secretion + 0
            negative regulation of dopamine secretion 7
            positive regulation of dopamine secretion 10
            regulation of dopamine secretion + 31
            somato-dendritic dopamine secretion 0
Path 2
Term Annotations click to browse term
  biological_process 12561
    localization 4922
      establishment of localization 3510
        transport 3358
          organic substance transport 1736
            monoamine transport 91
              catecholamine transport 74
                dopamine transport 46
                  dopamine secretion 31
                    axonal dopamine secretion + 0
                    negative regulation of dopamine secretion 7
                    positive regulation of dopamine secretion 10
                    regulation of dopamine secretion + 31
                    somato-dendritic dopamine secretion 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.