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ONTOLOGY REPORT - ANNOTATIONS


Term:dopamine secretion
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Accession:GO:0014046 term browser browse the term
Definition:The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone.



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dopamine secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of ISO MGI:1926253 (PMID:9428762) RGD PMID:9428762 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Comt catechol-O-methyltransferase acts_upstream_of_or_within ISO MGI:2178542 (PMID:12188925), (PMID:17881525), (PMID:24509724), (PMID:24639487), (PMID:30238463) RGD PMID:12188925 PMID:17881525 PMID:24509724 PMID:24639487 PMID:30238463 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Gnat1 G protein subunit alpha transducin 1 acts_upstream_of_or_within ISO MGI:2152779 (PMID:30799247) RGD PMID:30799247 NCBI chr 8:108,350,935...108,355,671
Ensembl chr 8:108,350,935...108,355,671
JBrowse link
G Kpna4 karyopherin subunit alpha 4 acts_upstream_of_positive_effect ISO (PMID:32273471) RGD PMID:32273471 NCBI chr 2:153,319,380...153,381,085
Ensembl chr 2:153,324,273...153,381,081
JBrowse link
G Pink1 PTEN induced kinase 1 acts_upstream_of ISO MGI:3716083 (PMID:17563363) RGD PMID:17563363 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Tgm2 transglutaminase 2 acts_upstream_of_positive_effect
involved_in
ISO
IEA
(PMID:32273471)
GO_REF:0000107
RGD
Ensembl
PMID:32273471 GO_REF:0000107 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
JBrowse link
negative regulation of dopamine secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:590329 RGD:10047092 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
JBrowse link
G C5 complement C5 IDA RGD PMID:18648551 RGD:5130170 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
JBrowse link
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:19187091 RGD:2314679 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Drd2 dopamine receptor D2 IMP RGD PMID:16490190 RGD:1625068 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 IMP RGD PMID:21325440 RGD:9685453 NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 IDA RGD PMID:12872287 RGD:2315496 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994
JBrowse link
G Myo5a myosin VA IMP RGD PMID:22639889 RGD:42722007 NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918
JBrowse link
G Syt11 synaptotagmin 11 involved_in ISO
IEA
IDA
(MGI:6114813|PMID:29311685)
(PMID:29311685)
GO_REF:0000107
RGD
Ensembl
PMID:29311685 PMID:29311685 GO_REF:0000107 MGI:6114813, RGD:14929208 NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964
JBrowse link
positive regulation of dopamine secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO MGI:1926253 (PMID:9428762) RGD PMID:9428762 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IDA RGD PMID:18671738 RGD:2306573 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 IMP RGD PMID:16987217 RGD:2317005 NCBI chr 5:151,295,269...151,312,853
Ensembl chr 5:151,296,662...151,311,912
JBrowse link
G Npy2r neuropeptide Y receptor Y2 IMP RGD PMID:17382974 RGD:1642505 NCBI chr 2:167,901,999...167,912,165
Ensembl chr 2:167,903,879...167,905,024
JBrowse link
G Oprk1 opioid receptor, kappa 1 IDA RGD PMID:17568430 RGD:9831445 NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823
JBrowse link
G Pcp4 Purkinje cell protein 4 IMP RGD PMID:21671256 RGD:9850149 NCBI chr11:35,759,711...35,861,725
Ensembl chr11:35,800,713...35,861,725
JBrowse link
G Pink1 PTEN induced kinase 1 acts_upstream_of_or_within ISO MGI:3716083 (PMID:17563363) RGD PMID:17563363 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Rtn4 reticulon 4 IMP RGD PMID:19112410 RGD:2314933 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686
JBrowse link
G Slc18a1 solute carrier family 18 member A1 IMP RGD PMID:17244889 RGD:5131195 NCBI chr16:20,653,268...20,687,051
Ensembl chr16:20,653,508...20,687,051
JBrowse link
G Syt1 synaptotagmin 1 involved_in IMP PMID:28370453 CACAO PMID:28370453 RGD:15023476 NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803
JBrowse link
regulation of dopamine secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit acts_upstream_of_or_within ISO MGI:1926251 (PMID:12944511) RGD PMID:12944511 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrna6 cholinergic receptor nicotinic alpha 6 subunit involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2179133 (PMID:12944511)
Ensembl
RGD
PMID:12944511 GO_REF:0000107 NCBI chr16:64,697,741...64,704,441
Ensembl chr16:64,697,741...64,704,441
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO MGI:1926253 (PMID:12944511) RGD PMID:12944511 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Drd2 dopamine receptor D2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Drd3 dopamine receptor D3 acts_upstream_of_or_within
involved_in
IMP
ISO
IBA
MGI:3044114|MGI:3698033 (PMID:12044470), (PMID:9482807)
GO_REF:0000033
RGD
GO_Central
PMID:9482807 PMID:12044470 PMID:16490190 GO_REF:0000033, RGD:1625068 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 involved_in ISO
ISS
(MGI:4398782|PMID:19887632)
(PMID:19887632)
GO_REF:0000024
RGD
UniProt
PMID:19887632 GO_REF:0000024 MGI:4398782 NCBI chr17:19,685,218...19,776,668
Ensembl chr17:19,685,215...19,776,661
JBrowse link
G Grm2 glutamate metabotropic receptor 2 IMP RGD PMID:30283001 RGD:38501063 NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B IMP RGD PMID:16885935 RGD:1626459 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IMP RGD PMID:15999145 RGD:1624397 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:21233214)
(MGI:4947004|PMID:21233214)
UniProt
RGD
PMID:21233214 GO_REF:0000024 MGI:4947004 NCBI chr 2:194,704,555...194,718,387
Ensembl chr 2:194,704,639...194,718,400
JBrowse link
G Prkcb protein kinase C, beta IMP RGD PMID:15647254 RGD:1625522 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Rab3a RAB3A, member RAS oncogene family involved_in IDA PMID:28370453 CACAO PMID:28370453 RGD:15023476 NCBI chr16:18,684,185...18,688,297
Ensembl chr16:18,684,188...18,688,336
JBrowse link
G Snca synuclein alpha involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000002
MGI:1298397 (PMID:18333965)
InterPro
RGD
PMID:18333965 GO_REF:0000002 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sncg synuclein, gamma involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1277151 (PMID:18333965)
Ensembl
RGD
PMID:18333965 GO_REF:0000107 NCBI chr16:9,700,513...9,705,751
Ensembl chr16:9,700,514...9,705,368
JBrowse link
G Syt1 synaptotagmin 1 involved_in ISO (MGI:5795818|PMID:21576241)
(PMID:21576241)
RGD PMID:21576241 MGI:5795818 NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803
JBrowse link
G Syt4 synaptotagmin 4 involved_in ISO (MGI:5795818|PMID:21576241)
(PMID:21576241)
RGD PMID:21576241 MGI:5795818 NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332
JBrowse link
G Syt7 synaptotagmin 7 involved_in ISO (MGI:5795818|PMID:21576241)
(PMID:21576241)
RGD PMID:21576241 MGI:5795818 NCBI chr 1:207,031,359...207,093,787
Ensembl chr 1:207,031,592...207,089,026
JBrowse link
somato-dendritic dopamine secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc18a2 solute carrier family 18 member A2 involved_in IDA PMID:16301178 UniProt PMID:16301178 RGD:155663549 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20134
    regulation of biological process 13139
      signaling 7651
        cell-cell signaling 1464
          signal release 649
            dopamine secretion 38
              axonal dopamine secretion + 0
              negative regulation of dopamine secretion 9
              positive regulation of dopamine secretion 10
              regulation of dopamine secretion + 33
              somato-dendritic dopamine secretion 1
Path 2
Term Annotations click to browse term
  biological_process 20134
    localization 5690
      establishment of localization 4993
        transport 4686
          nitrogen compound transport 1998
            monoamine transport 105
              catecholamine transport 88
                catecholamine secretion 69
                  dopamine secretion 38
                    axonal dopamine secretion + 0
                    negative regulation of dopamine secretion 9
                    positive regulation of dopamine secretion 10
                    regulation of dopamine secretion + 33
                    somato-dendritic dopamine secretion 1
paths to the root