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ONTOLOGY REPORT - ANNOTATIONS

Term:establishment of endothelial blood-brain barrier
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Accession:GO:0014045 term browser browse the term
Definition:Establishment of the endothelial barrier between the blood and the brain. The endothelial cells in the brain capillaries are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.
Synonyms:exact_synonym: establishment of endothelial BBB


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establishment of endothelial blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, sub-family B member 1B involved_in ISO RGD
MGI		 PMID:16850390 GO_REF:0000096 MGI:4417868 RGD:1598561 NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315 		JBrowse link
G Cldn3 claudin 3 involved_in IMP (MGI:6368952|PMID:12734665) ARUK-UCL PMID:12734665 MGI:6368952 NCBI chr 5:135,015,068...135,016,330
Ensembl chr 5:135,015,068...135,016,326 		JBrowse link
G Foxp3 forkhead box P3 ISO RGD PMID:31027862 RGD:38549575 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    developmental process 7369
      anatomical structure development 6841
        cell development 3447
          establishment of blood-brain barrier 20
            establishment of endothelial blood-brain barrier 3
Path 2
Term Annotations click to browse term
  biological_process 28573
    developmental process 7369
      anatomical structure development 6841
        tissue development 2361
          epithelium development 1458
            endothelium development 170
              endothelial cell differentiation 144
                endothelial cell development 80
                  establishment of endothelial barrier 59
                    establishment of endothelial blood-brain barrier 3
paths to the root