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ONTOLOGY REPORT - ANNOTATIONS


Term:glial cell proliferation
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Accession:GO:0014009 term browser browse the term
Definition:The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others.
Synonyms:exact_synonym: glia proliferation


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glial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Areg amphiregulin IDA RGD PMID:2234093 RGD:69755 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein IDA RGD PMID:10899945 RGD:2316280 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 IEP RGD PMID:7696190 RGD:10401648 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
JBrowse link
G Epm2a EPM2A glucan phosphatase, laforin acts_upstream_of_or_within ISO MGI:104993 (MGI:6094295|PMID:28973665) RGD PMID:28973665 MGI:6094295 NCBI chr 1:5,727,111...5,845,338
Ensembl chr 1:5,727,066...5,920,555
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 IEP RGD PMID:8919308 RGD:729202 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
JBrowse link
G Lepr leptin receptor acts_upstream_of_or_within ISO MGI:1341085 (MGI:6094295|PMID:28973665) RGD PMID:28973665 MGI:6094295 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Lgi4 leucine-rich repeat LGI family, member 4 acts_upstream_of_or_within ISO (MGI:4845793|PMID:21068328) RGD PMID:21068328 MGI:4845793 NCBI chr 1:86,294,539...86,305,909
Ensembl chr 1:86,295,074...86,304,874
JBrowse link
G Penk proenkephalin IEP RGD PMID:9221949 RGD:9999373 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IEP RGD PMID:11389173 RGD:1642644 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link
G Sox11 SRY-box transcription factor 11 involved_in ISS
ISO
GO_REF:0000024
(MGI:4437361|PMID:20147379)
UniProt
RGD
PMID:20147379 GO_REF:0000024 MGI:4437361 NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354
JBrowse link
G Sox4 SRY-box transcription factor 4 involved_in ISO (MGI:4437361|PMID:20147379) RGD PMID:20147379 MGI:4437361 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665
JBrowse link
microglial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clu clusterin involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:15857407)
Ensembl
Alzheimers_University_of_Toronto
RGD
PMID:15857407 GO_REF:0000024 GO_REF:0000107 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Csf1 colony stimulating factor 1 involved_in ISO UniProtKB:P09581 (MGI:6274943|PMID:23392676) RGD PMID:23392676 MGI:6274943 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Csf1r colony stimulating factor 1 receptor involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P07141|UniProtKB:Q8R1R4 (MGI:6274943|PMID:23392676)
Ensembl
RGD
PMID:23392676 GO_REF:0000107 MGI:6274943 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in ISO
IEA
(PMID:12125082)
GO_REF:0000107
RGD
Ensembl
PMID:12125082 GO_REF:0000107 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Gba glucosylceramidase beta acts_upstream_of_or_within ISO (MGI:3762988|PMID:17954912) RGD PMID:17954912 MGI:3762988 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263
JBrowse link
G Il33 interleukin 33 involved_in IEA
ISO
GO_REF:0000107
(MGI:5008219|PMID:21349253)
Ensembl
RGD
PMID:21349253 GO_REF:0000107 MGI:5008219 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Il34 interleukin 34 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P09581 (MGI:6274943|PMID:23392676)
Ensembl
RGD
PMID:23392676 GO_REF:0000107 MGI:6274943 NCBI chr19:38,714,990...38,782,749
Ensembl chr19:38,714,991...38,764,000
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6304666|PMID:25631124) RGD PMID:25631124 MGI:6304666 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
negative regulation of glial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 IMP RGD PMID:23149556 RGD:12790979 NCBI chr 1:96,598,663...96,679,495
Ensembl chr 1:96,598,647...96,679,510
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 IDA RGD PMID:15870074 RGD:2325307 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B IMP RGD PMID:26526028 RGD:11252201 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Dicer1 dicer 1 ribonuclease III acts_upstream_of_or_within ISO GO:0060253 (MGI:4830414|PMID:20805985) RGD PMID:20805985 MGI:4830414 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:2655020|PMID:12666205)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:12666205 GO_REF:0000024 GO_REF:0000107 MGI:2655020 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 IMP RGD PMID:21641335 RGD:11522736 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:25017825 RGD:13204822 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Notch1 notch receptor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:2655020|PMID:12666205)
UniProt
RGD
PMID:12666205 GO_REF:0000024 MGI:2655020 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Ptn pleiotrophin IMP RGD PMID:17881084 RGD:2292001 NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456
JBrowse link
G Sox11 SRY-box transcription factor 11 involved_in ISS
ISO
GO_REF:0000024
(MGI:5285167|PMID:19808959)
(PMID:19808959)
UniProt
RGD
PMID:19808959 GO_REF:0000024 MGI:5285167 NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354
JBrowse link
G Tert telomerase reverse transcriptase IDA RGD PMID:21940960 RGD:11038672 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tspo translocator protein IDA RGD PMID:14678758 RGD:2317158 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
JBrowse link
negative regulation of Schwann cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl2 achaete-scute family bHLH transcription factor 2 IDA RGD PMID:12196582 RGD:625617 NCBI chr 1:198,148,999...198,151,406
Ensembl chr 1:198,148,999...198,151,406
JBrowse link
G Dicer1 dicer 1 ribonuclease III involved_in ISO (MGI:4830414|PMID:20805985) RGD PMID:20805985 MGI:4830414 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
JBrowse link
G Fas Fas cell surface death receptor IMP RGD PMID:29970988 RGD:13792563 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Rnf10 ring finger protein 10 involved_in IDA PMID:18941509 UniProt PMID:18941509 RGD:8553607 NCBI chr12:41,341,717...41,375,505
Ensembl chr12:41,341,717...41,375,504
JBrowse link
G Ski SKI proto-oncogene acts_upstream_of_or_within ISO UniProtKB:P01137 (PMID:15312649) RGD PMID:15312649 NCBI chr 5:165,713,525...165,782,134
Ensembl chr 5:165,714,093...165,782,733
JBrowse link
G Sox10 SRY-box transcription factor 10 IMP RGD PMID:25536222 RGD:12879826 NCBI chr 7:110,725,274...110,735,544
Ensembl chr 7:110,725,274...110,735,544
JBrowse link
negative regulation of Schwann cell proliferation involved in axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cers2 ceramide synthase 2 involved_in IMP PMID:22393241 BHF-UCL PMID:22393241 RGD:11041067 NCBI chr 2:182,890,527...182,898,805
Ensembl chr 2:182,890,493...182,933,314
JBrowse link
positive regulation of glial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atxn1 ataxin 1 acts_upstream_of_or_within ISO (MGI:4462742|PMID:20531390) RGD PMID:20531390 MGI:4462742 NCBI chr17:18,737,491...19,142,360
Ensembl chr17:18,737,533...19,142,360
JBrowse link
G E2f1 E2F transcription factor 1 IMP RGD PMID:21637599 RGD:13702469 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G Egfr epidermal growth factor receptor IMP RGD PMID:10616092 RGD:38599219 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Etv5 ETS variant transcription factor 5 IMP RGD PMID:12297104 RGD:2316288 NCBI chr11:78,608,618...78,666,221
Ensembl chr11:78,608,710...78,666,215
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 IMP RGD PMID:18482723 RGD:10402148 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Gfap glial fibrillary acidic protein IMP RGD PMID:21250919 RGD:6480511 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Igf1 insulin-like growth factor 1 IDA RGD PMID:24262632 RGD:12904964 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il1b interleukin 1 beta involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P01375 (PMID:1752215)
Ensembl
RGD
PMID:1752215 GO_REF:0000107 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:2104886) RGD PMID:2104886 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Lta lymphotoxin alpha IMP RGD PMID:11595667 RGD:8548857 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IDA RGD PMID:15504915 RGD:2303714 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:19576187 RGD:10041012 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Myb MYB proto-oncogene, transcription factor IMP RGD PMID:12599418 RGD:11532679 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IMP RGD PMID:9316053 RGD:10059624 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Plag1 PLAG1 zinc finger involved_in ISO (MGI:5285167|PMID:19808959) RGD PMID:19808959 MGI:5285167 NCBI chr 5:16,902,057...16,956,727
Ensembl chr 5:16,905,394...16,913,647
JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma IMP RGD PMID:29033188 RGD:13514047 NCBI chr12:34,383,072...34,400,553
Ensembl chr12:34,383,072...34,400,553
JBrowse link
G Prkch protein kinase C, eta involved_in ISO
ISS
(PMID:10806212)
GO_REF:0000024
RGD
UniProt
PMID:10806212 GO_REF:0000024 NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654
JBrowse link
G Prkci protein kinase C, iota involved_in ISO
ISS
(PMID:21419810)
GO_REF:0000024
RGD
UniProt
PMID:21419810 GO_REF:0000024 NCBI chr 2:112,321,919...112,382,305
Ensembl chr 2:112,321,929...112,382,352
JBrowse link
G Ptk2 protein tyrosine kinase 2 IMP RGD PMID:12838510 RGD:2292612 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Tnf tumor necrosis factor involved_in ISO UniProtKB:P01584 (PMID:1752215), (PMID:2104886) RGD PMID:1752215 PMID:2104886 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tspo translocator protein IDA RGD PMID:18190798 RGD:2317142 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
JBrowse link
G Ufl1 Ufm1-specific ligase 1 acts_upstream_of_or_within ISO (MGI:4462742|PMID:20531390) RGD PMID:20531390 MGI:4462742 NCBI chr 5:38,962,721...38,995,134
Ensembl chr 5:38,962,171...38,995,199
JBrowse link
G Vim vimentin IMP RGD PMID:21250919 RGD:6480511 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
positive regulation of Schwann cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gfap glial fibrillary acidic protein acts_upstream_of_or_within ISO MGI:1857176 (MGI:3664718|PMID:16988027) RGD PMID:16988027 MGI:3664718 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Nrg1 neuregulin 1 IMP RGD PMID:9417836 RGD:10449005 NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884
JBrowse link
regulation of glial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Creb1 cAMP responsive element binding protein 1 IMP RGD PMID:19365572 RGD:10059410 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Ifng interferon gamma IDA RGD PMID:10598324 RGD:10755759 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
regulation of Schwann cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO MGI:2447704 (MGI:3607056|PMID:11673320) RGD PMID:11673320 MGI:3607056 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
JBrowse link
Schwann cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 IMP RGD PMID:17941050 RGD:2289839 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 IEP RGD PMID:22659073 RGD:9590073 NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
JBrowse link
G Nf2 neurofibromin 2 involved_in ISO
IEA
(PMID:17353411)
GO_REF:0000107
RGD
Ensembl
PMID:17353411 GO_REF:0000107 NCBI chr14:79,627,399...79,710,709
Ensembl chr14:79,627,399...79,710,667
JBrowse link
G Snw1 SNW domain containing 1 IEP RGD PMID:23389663 RGD:11035242 NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    cellular process 18340
      cell population proliferation 2153
        glial cell proliferation 66
          Schwann cell proliferation + 14
          microglial cell proliferation 8
          negative regulation of glial cell proliferation + 18
          positive regulation of glial cell proliferation + 24
          regulation of glial cell proliferation + 44
Path 2
Term Annotations click to browse term
  biological_process 19492
    developmental process 6769
      anatomical structure development 6195
        multicellular organism development 5632
          system development 5300
            nervous system development 2732
              neurogenesis 1952
                gliogenesis 383
                  glial cell proliferation 66
                    Schwann cell proliferation + 14
                    microglial cell proliferation 8
                    negative regulation of glial cell proliferation + 18
                    positive regulation of glial cell proliferation + 24
                    regulation of glial cell proliferation + 44
paths to the root