Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:microglia differentiation
go back to main search page
Accession:GO:0014004 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system.
Synonyms:exact_synonym: microglial cell differentiation



show annotations for term's descendants           Sort by:
microglia differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO MGI:1857079 (PMID:23717624) RGD PMID:23717624 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
JBrowse link
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (PMID:17954912) RGD PMID:17954912 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263
JBrowse link
G Mfsd8 major facilitator superfamily domain containing 8 acts_upstream_of_or_within ISO (PMID:27654426) RGD PMID:27654426 NCBI chr 2:123,822,042...123,847,808
Ensembl chr 2:123,816,614...123,857,971
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of_or_within ISO MGI:2385681 (PMID:18509511) RGD PMID:18509511 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO MGI:1934018 (PMID:18509511) RGD PMID:18509511 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972
JBrowse link
G Ndp norrin cystine knot growth factor NDP acts_upstream_of_or_within ISO MGI:2676199 (PMID:29654250) RGD PMID:29654250 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:29890290)
Ensembl
RGD
PMID:29890290 GO_REF:0000107 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Qki QKI, KH domain containing RNA binding involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:6514532|PMID:33378678)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:33378678 GO_REF:0000024 GO_REF:0000107 MGI:6514532 NCBI chr 1:50,387,716...50,501,568
Ensembl chr 1:50,387,698...50,498,831
JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1860885 (PMID:18509511)
Ensembl
RGD
PMID:18509511 GO_REF:0000107 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Vps13a vacuolar protein sorting 13 homolog A acts_upstream_of_or_within ISO (PMID:37714309) RGD PMID:37714309 NCBI chr 1:213,901,999...214,128,638
Ensembl chr 1:213,901,999...214,128,555
JBrowse link
G Vps54 VPS54 subunit of GARP complex involved_in IEA
ISO
GO_REF:0000107
MGI:1857091 (PMID:29890290)
Ensembl
RGD
PMID:29890290 GO_REF:0000107 NCBI chr14:95,378,821...95,455,871
Ensembl chr14:95,378,012...95,455,857
JBrowse link
microglia development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO
IEA
UniProtKB:P49768|UniProtKB:Q9QUN7 (PMID:22198949)
GO_REF:0000107
RGD
Ensembl
PMID:22198949 GO_REF:0000107 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:33450391 RGD:126781687 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Itgam integrin subunit alpha M acts_upstream_of_or_within ISO (PMID:20578039) RGD PMID:20578039 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Nrros negative regulator of reactive oxygen species involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:6141908|PMID:28459434), (MGI:6192878|PMID:29909984)
UniProt
Ensembl
RGD
PMID:28459434 PMID:29909984 GO_REF:0000024 GO_REF:0000107 MGI:6141908 MGI:6192878 NCBI chr11:68,628,641...68,646,152
Ensembl chr11:68,628,712...68,646,142
JBrowse link
G Tlr2 toll-like receptor 2 involved_in ISO UniProtKB:P05067|UniProtKB:P49768 (MGI:5307186|PMID:22198949) RGD PMID:22198949 MGI:5307186 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tspan2 tetraspanin 2 acts_upstream_of_or_within ISO MGI:5556057|MGI:97623 (PMID:24038504) RGD PMID:24038504 NCBI chr 2:190,177,717...190,234,994
Ensembl chr 2:190,177,741...190,219,660
JBrowse link
positive regulation of microglia differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:6192878|PMID:29909984)
UniProt
RGD
PMID:29909984 GO_REF:0000024 MGI:6192878 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19872
    developmental process 6994
      cellular developmental process 4721
        cell differentiation 4720
          glial cell differentiation 326
            microglia differentiation 18
              microglia development 6
              negative regulation of microglia differentiation 0
              positive regulation of microglia differentiation 1
              regulation of microglia differentiation + 1
Path 2
Term Annotations click to browse term
  biological_process 19872
    developmental process 6994
      anatomical structure development 6515
        multicellular organism development 5259
          system development 4544
            nervous system development 2815
              neurogenesis 2077
                gliogenesis 442
                  glial cell differentiation 326
                    microglia differentiation 18
                      microglia development 6
                      negative regulation of microglia differentiation 0
                      positive regulation of microglia differentiation 1
                      regulation of microglia differentiation + 1
paths to the root