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ONTOLOGY REPORT - ANNOTATIONS

Term:oligodendrocyte development
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Accession:GO:0014003 term browser browse the term
Definition:The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system.
Synonyms:exact_synonym: oligodendrocyte cell development


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oligodendrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:1857470 (PMID:18287202) RGD PMID:18287202 NCBI chr 7:21,903,136...21,906,003
Ensembl chr 7:21,903,126...21,905,993 		JBrowse link
G Cd9 CD9 molecule IEP RGD PMID:12420314 RGD:2326210 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222 		JBrowse link
G Cers5 ceramide synthase 5 IEP RGD PMID:21148554 RGD:156431059 NCBI chr 7:130,859,993...130,897,979
Ensembl chr 7:130,859,990...130,897,947 		JBrowse link
G Cers6 ceramide synthase 6 IEP RGD PMID:21148554 RGD:156431059 NCBI chr 3:53,630,637...53,879,692
Ensembl chr 3:53,630,959...53,876,848 		JBrowse link
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:15217090)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:15217090 GO_REF:0000024 GO_REF:0000107 NCBI chr12:32,025,593...32,033,848
Ensembl chr12:32,025,557...32,046,601 		JBrowse link
G Eif2b2 eukaryotic translation initiation factor 2B subunit beta involved_in ISO
IEA
ISS		 (PMID:15217090)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:15217090 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:104,866,926...104,873,351
Ensembl chr 6:104,866,753...104,873,353 		JBrowse link
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15217090)		 UniProt
Ensembl
RGD		 PMID:15217090 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:130,492,167...130,558,692
Ensembl chr 5:130,492,220...130,563,332 		JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15217090)		 UniProt
Ensembl
RGD		 PMID:15217090 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:25,183,177...25,188,832
Ensembl chr 6:25,183,186...25,188,829 		JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon involved_in ISO
ISS		 (PMID:15217090)
GO_REF:0000024		 RGD
UniProt		 PMID:15217090 GO_REF:0000024 NCBI chr11:80,394,433...80,404,468
Ensembl chr11:80,394,433...80,404,419 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:1931521 (PMID:12574417) RGD PMID:12574417 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Gsn gelsolin IEP RGD PMID:7817780 RGD:1599870 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 IEP RGD PMID:17681700 RGD:2317862 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hdac10 histone deacetylase 10 IEP RGD PMID:18627006 RGD:2306445 NCBI chr 7:120,199,126...120,205,850
Ensembl chr 7:120,199,129...120,204,228 		JBrowse link
G Hdac11 histone deacetylase 11 IMP RGD PMID:18627006 RGD:2306445 NCBI chr 4:123,645,873...123,667,407
Ensembl chr 4:123,650,157...123,667,405 		JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:2149674 (PMID:17006542)		 UniProt
RGD		 PMID:17006542 GO_REF:0000024 NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001 		JBrowse link
G Id2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO MGI:2384134 (PMID:11301021) RGD PMID:11301021 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 acts_upstream_of_or_within ISO MGI:3655847|MGI:3761690 (PMID:17942730) RGD PMID:17942730 NCBI chr13:84,802,026...84,835,383
Ensembl chr13:84,802,009...84,835,461 		JBrowse link
G Kcnq3 potassium voltage-gated channel subfamily Q member 3 IEP RGD PMID:21750731 RGD:9686431 NCBI chr 7:97,730,219...98,025,652
Ensembl chr 7:97,730,465...98,025,653 		JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 IEP RGD PMID:11948806 RGD:10054294 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IEP RGD PMID:15504915 RGD:2303714 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Mecp2 methyl CpG binding protein 2 IEP RGD PMID:26140854 RGD:11343660 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689 		JBrowse link
G Med12 mediator complex subunit 12 acts_upstream_of_or_within ISO MGI:4839485 (PMID:23575864) RGD PMID:23575864 NCBI chr  X:66,404,807...66,427,775
Ensembl chr  X:66,404,760...66,428,387 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase IEP RGD PMID:17382307 RGD:2317494 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Myrf myelin regulatory factor involved_in ISO (MGI:3850982|PMID:19596243), (MGI:5544144|PMID:24204311), (MGI:5805298|PMID:27532821), (MGI:6450350|PMID:31828317) RGD PMID:19596243 PMID:24204311 PMID:27532821 PMID:31828317 MGI:3850982 MGI:5544144 MGI:5805298 MGI:6450350 NCBI chr 1:206,854,175...206,886,276
Ensembl chr 1:206,854,175...206,886,157 		JBrowse link
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO MGI:1932100 (PMID:11526078) RGD PMID:11526078 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411 		JBrowse link
G Nsun5 NOP2/Sun RNA methyltransferase 5 involved_in ISO (MGI:6280591|PMID:30485550), (MGI:6359541|PMID:31174389) RGD PMID:30485550 PMID:31174389 MGI:6280591 MGI:6359541 NCBI chr12:21,293,637...21,299,319
Ensembl chr12:21,293,645...21,299,272 		JBrowse link
G Olig1 oligodendrocyte transcription factor 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5632010|PMID:25762682)		 Ensembl
RGD		 PMID:25762682 GO_REF:0000107 MGI:5632010 NCBI chr11:30,514,379...30,516,521
Ensembl chr11:30,514,379...30,516,521 		JBrowse link
G Prdm8 PR/SET domain 8 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:11,403,202...11,424,059
Ensembl chr14:11,404,407...11,410,993 		JBrowse link
G Robo1 roundabout guidance receptor 1 IEP RGD PMID:22433866 RGD:243048458 NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:8660874)		 Ensembl
RGD		 PMID:8660874 GO_REF:0000107 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Sox10 SRY-box transcription factor 10 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5544144|PMID:24204311), (MGI:5805298|PMID:27532821)		 UniProt
RGD		 PMID:24204311 PMID:27532821 GO_REF:0000024 MGI:5544144 MGI:5805298 NCBI chr 7:110,725,274...110,734,651
Ensembl chr 7:110,725,274...110,735,544 		JBrowse link
G Sox11 SRY-box transcription factor 11 IEP RGD PMID:9632656 RGD:68859 NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO MGI:1926344 (PMID:19741146) RGD PMID:19741146 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (MGI:5619741|PMID:22384214) RGD PMID:22384214 MGI:5619741 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tppp tubulin polymerization promoting protein involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:6368053|PMID:31522887)		 UniProt
Ensembl
RGD		 PMID:31522887 GO_REF:0000024 GO_REF:0000107 MGI:6368053 NCBI chr 1:29,257,111...29,281,134
Ensembl chr 1:29,261,255...29,281,134 		JBrowse link
G Wasf3 WASP family member 3 acts_upstream_of_or_within ISO MGI:2663235 (PMID:16723544) RGD PMID:16723544 NCBI chr12:8,563,805...8,660,799
Ensembl chr12:8,562,062...8,660,751 		JBrowse link
G Zfp488 zinc finger protein 488 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:16908628)		 GO_Central
RGD		 PMID:16908628 GO_REF:0000033 NCBI chr16:9,283,039...9,293,681
Ensembl chr16:9,283,043...9,293,671 		JBrowse link
central nervous system myelin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in
acts_upstream_of_or_within		 IDA
ISO		 PMID:12210128
(MGI:3697245|PMID:17060448)		 RGD PMID:17060448 PMID:12210128 MGI:3697245, RGD:631995 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537 		JBrowse link
G Ckap5 cytoskeleton associated protein 5 acts_upstream_of_or_within ISO MGI:3051635|MGI:5570192 (PMID:28063167) RGD PMID:28063167 NCBI chr 3:77,491,195...77,593,300
Ensembl chr 3:77,491,276...77,593,264 		JBrowse link
G Cntn1 contactin 1 involved_in IEA
ISO		 GO_REF:0000107
MGI:96912 (PMID:31641127)		 Ensembl
RGD		 PMID:31641127 GO_REF:0000107 NCBI chr 7:123,263,146...123,560,896
Ensembl chr 7:123,372,792...123,558,541 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit acts_upstream_of_or_within ISO MGI:2183949 (PMID:17952069) RGD PMID:17952069 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102 		JBrowse link
G Mag myelin-associated glycoprotein involved_in ISO MGI:105980 (PMID:31641127) RGD PMID:31641127 NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656 		JBrowse link
G Mios meiosis regulator for oocyte development involved_in ISO (MGI:6870482|PMID:35022234) RGD PMID:35022234 MGI:6870482 NCBI chr 4:36,263,419...36,289,546
Ensembl chr 4:36,263,968...36,289,544 		JBrowse link
G Mobp myelin-associated oligodendrocyte basic protein IEP RGD PMID:9306245 RGD:27226697 NCBI chr 8:119,869,504...119,899,605
Ensembl chr 8:119,869,626...119,899,563 		JBrowse link
G Tenm4 teneurin transmembrane protein 4 involved_in ISO (PMID:26188006)
(MGI:5437806|PMID:22915103)		 RGD PMID:22915103 PMID:26188006 MGI:5437806 NCBI chr 1:149,895,097...151,263,315
Ensembl chr 1:150,780,381...151,259,144 		JBrowse link
G Tlr2 toll-like receptor 2 IDA RGD PMID:21971760 RGD:7241097 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
central nervous system myelin maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clu clusterin involved_in ISO
ISS
IEA		 (PMID:21543606)
GO_REF:0000024
GO_REF:0000107		 RGD
Alzheimers_University_of_Toronto
Ensembl		 PMID:21543606 GO_REF:0000024 GO_REF:0000107 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Fa2h fatty acid 2-hydroxylase acts_upstream_of_or_within ISO MGI:3829000|MGI:4430585 (PMID:18815260), (PMID:21491498) RGD PMID:18815260 PMID:21491498 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153 		JBrowse link
G Myrf myelin regulatory factor involved_in ISO
IBA		 (MGI:5437779|PMID:22956843)
GO_REF:0000033		 RGD
GO_Central		 PMID:22956843 GO_REF:0000033 MGI:5437779 NCBI chr 1:206,854,175...206,886,276
Ensembl chr 1:206,854,175...206,886,157 		JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (MGI:3772418|PMID:18082964) RGD PMID:18082964 MGI:3772418 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
central nervous system myelination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspa aspartoacylase IEP RGD PMID:12524181 RGD:632029 NCBI chr10:57,891,704...57,945,267
Ensembl chr10:57,892,104...57,945,272 		JBrowse link
G B4galt5 beta-1,4-galactosyltransferase 5 involved_in ISO (MGI:6196231|PMID:30114188) RGD PMID:30114188 MGI:6196231 NCBI chr 3:156,018,056...156,033,983
Ensembl chr 3:156,018,053...156,070,074 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6196231|PMID:30114188)		 UniProt
RGD		 PMID:30114188 GO_REF:0000024 MGI:6196231 NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247 		JBrowse link
G Cntn2 contactin 2 acts_upstream_of_or_within ISO MGI:2181052 (PMID:18650339) RGD PMID:18650339 NCBI chr13:43,942,868...43,975,973
Ensembl chr13:43,947,265...43,975,887 		JBrowse link
G Cntnap1 contactin associated protein 1 involved_in ISO
ISS		 (PMID:28374019)
GO_REF:0000024		 RGD
UniProt		 PMID:28374019 GO_REF:0000024 NCBI chr10:86,109,850...86,125,612
Ensembl chr10:86,111,643...86,125,611 		JBrowse link
G Cntnap2 contactin associated protein 2 involved_in ISO MGI:2677631 (PMID:29300891) RGD PMID:29300891 NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO MGI:1857079 (PMID:21935678) RGD PMID:21935678 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:1931521 (PMID:12574417) RGD PMID:12574417 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Gpm6b glycoprotein m6b involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:28,057,788...28,204,409
Ensembl chr  X:28,059,450...28,204,211 		JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:2149674 (PMID:17006542)		 UniProt
RGD		 PMID:17006542 GO_REF:0000024 NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001 		JBrowse link
G Id4 inhibitor of DNA binding 4 acts_upstream_of_or_within ISO MGI:3579084 (PMID:16862533) RGD PMID:16862533 NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470 		JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3655847|MGI:3761690 (PMID:17942730)		 Ensembl
RGD		 PMID:17942730 GO_REF:0000107 NCBI chr13:84,802,026...84,835,383
Ensembl chr13:84,802,009...84,835,461 		JBrowse link
G Mag myelin-associated glycoprotein involved_in ISO (MGI:1202048|PMID:9482783) RGD PMID:9482783 MGI:1202048 NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656 		JBrowse link
G Mal mal, T-cell differentiation protein acts_upstream_of ISO MGI:3053860 (PMID:15337780) RGD PMID:15337780 NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136 		JBrowse link
G Myrf myelin regulatory factor involved_in ISO (MGI:3850982|PMID:19596243), (MGI:5544144|PMID:24204311), (MGI:5805298|PMID:27532821) RGD PMID:19596243 PMID:24204311 PMID:27532821 MGI:3850982 MGI:5544144 MGI:5805298 NCBI chr 1:206,854,175...206,886,276
Ensembl chr 1:206,854,175...206,886,157 		JBrowse link
G Ncstn nicastrin acts_upstream_of_or_within ISO MGI:3796837 (PMID:27008863) RGD PMID:27008863 NCBI chr13:84,530,442...84,546,454
Ensembl chr13:84,530,440...84,546,454 		JBrowse link
G Nkx6-2 NK6 homeobox 2 acts_upstream_of_or_within ISO MGI:3522433 (PMID:15601927) RGD PMID:15601927 NCBI chr 1:194,380,149...194,383,533
Ensembl chr 1:194,381,975...194,383,515 		JBrowse link
G Plp1 proteolipid protein 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1856067 (PMID:1694232)		 GO_Central
RGD		 PMID:1694232 GO_REF:0000033 NCBI chr  X:100,184,039...100,201,035
Ensembl chr  X:100,185,767...100,201,032 		JBrowse link
G Sox10 SRY-box transcription factor 10 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5544144|PMID:24204311), (MGI:5805298|PMID:27532821)		 UniProt
RGD		 PMID:24204311 PMID:27532821 GO_REF:0000024 MGI:5544144 MGI:5805298 NCBI chr 7:110,725,274...110,734,651
Ensembl chr 7:110,725,274...110,735,544 		JBrowse link
G Ulk4 unc-51 like kinase 4 acts_upstream_of_or_within ISO MGI:4362969 (PMID:29034508) RGD PMID:29034508 NCBI chr 8:120,670,879...120,966,026
Ensembl chr 8:120,670,866...120,966,924 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      anatomical structure development 6575
        cell development 3311
          glial cell development 155
            oligodendrocyte development 63
              central nervous system myelination + 31
Path 2
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      anatomical structure development 6575
        multicellular organism development 5290
          system development 4576
            nervous system development 2835
              neurogenesis 2096
                gliogenesis 441
                  glial cell differentiation 325
                    glial cell development 155
                      oligodendrocyte development 63
                        central nervous system myelination + 31
paths to the root