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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of translational initiation by eIF2 alpha phosphorylation
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Accession:GO:0010998 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha.
Comment:Consider also annotating to 'eukaryotic translation initiation factor 2alpha kinase activity ; GO:0004694'.
Synonyms:exact_synonym: eIF2 alpha phosphorylation in response to stress;   regulation of translational initiation by eIF2 alpha phosphorylation in response to stress


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negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:46,323,263...46,402,240
Ensembl chr22:46,307,905...46,398,625 		JBrowse link
G NCK1 NCK adaptor protein 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr23:33,297,660...33,374,025
Ensembl chr23:33,297,756...33,372,534 		JBrowse link
G NCK2 NCK adaptor protein 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:37,584,351...37,734,388
Ensembl chr10:37,585,565...37,732,994 		JBrowse link
G TMED2 transmembrane p24 trafficking protein 2 acts_upstream_of_or_within ISO (PMID:28797121) MGI PMID:28797121 NCBI chr26:6,039,046...6,047,490
Ensembl chr26:6,039,405...6,047,459 		JBrowse link
regulation of eIF2 alpha phosphorylation by dsRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPM1 nucleophosmin 1 involved_in ISO (PMID:12882984) UniProt PMID:12882984 NCBI chr 4:40,756,464...40,770,174
Ensembl chr 4:40,756,465...40,770,175 		JBrowse link
regulation of eIF2 alpha phosphorylation by heme term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15931390) Ensembl
MGI		 PMID:15931390 GO_REF:0000107 NCBI chr 6:11,447,225...11,478,611
Ensembl chr 6:11,447,081...11,478,658 		JBrowse link
G FECH ferrochelatase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15931390) Ensembl
MGI		 PMID:15931390 GO_REF:0000107 NCBI chr 1:18,352,184...18,384,251
Ensembl chr 1:18,345,811...18,383,092 		JBrowse link
G LOC609402 hemoglobin subunit beta-like acts_upstream_of_or_within ISO (PMID:15931390) MGI PMID:15931390 NCBI chr21:28,187,535...28,188,991 JBrowse link
regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO (MGI:3582244|PMID:11106749) UniProt PMID:11106749 MGI:3582244 NCBI chr17:37,886,397...37,950,671
Ensembl chr17:37,886,601...37,949,812 		JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A involved_in ISO (MGI:5605960|PMID:11381086) ParkinsonsUK-UCL PMID:11381086 MGI:5605960 NCBI chr 1:107,486,399...107,490,151
Ensembl chr 1:107,486,438...107,489,222 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17878
    metabolic process 10933
      primary metabolic process 9494
        protein metabolic process 4323
          protein modification process 1988
            protein phosphorylation 804
              regulation of translational initiation by eIF2 alpha phosphorylation 10
                eiF2alpha phosphorylation in response to endoplasmic reticulum stress + 6
                regulation of eIF2 alpha phosphorylation by dsRNA 1
                regulation of eIF2 alpha phosphorylation by heme 3
Path 2
Term Annotations click to browse term
  biological_process 17878
    biological regulation 12365
      regulation of biological process 12008
        regulation of cellular process 11539
          regulation of cellular metabolic process 5882
            regulation of cellular biosynthetic process 5129
              regulation of macromolecule biosynthetic process 4994
                regulation of gene expression 4876
                  post-transcriptional regulation of gene expression 816
                    regulation of translation 452
                      regulation of translational initiation 69
                        regulation of translational initiation in response to stress 14
                          regulation of translational initiation by eIF2 alpha phosphorylation 10
                            eiF2alpha phosphorylation in response to endoplasmic reticulum stress + 6
                            regulation of eIF2 alpha phosphorylation by dsRNA 1
                            regulation of eIF2 alpha phosphorylation by heme 3
paths to the root