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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of lipoprotein particle clearance
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Accession:GO:0010985 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.

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negative regulation of high-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:15778093) BHF-UCL PMID:15778093 NCBI chrNW_004955412:18,165,667...18,168,015
Ensembl chrNW_004955412:18,165,667...18,168,015 		JBrowse link
negative regulation of low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 ISO RGD PMID:23828271 RGD:12792253 NCBI chrNW_004955414:32,216,243...32,289,028
Ensembl chrNW_004955414:32,216,196...32,289,053 		JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:15778093) BHF-UCL PMID:15778093 NCBI chrNW_004955412:18,165,667...18,168,015
Ensembl chrNW_004955412:18,165,667...18,168,015 		JBrowse link
G Csk C-terminal Src kinase ISO RGD PMID:10884975 RGD:5134370 NCBI chrNW_004955450:3,127,561...3,144,550
Ensembl chrNW_004955450:3,127,561...3,144,550 		JBrowse link
G Il19 interleukin 19 involved_in ISO (MGI:6102526|PMID:28257760) BHF-UCL PMID:28257760 MGI:6102526 NCBI chrNW_004955406:42,376,102...42,384,902
Ensembl chrNW_004955406:42,376,104...42,384,902 		JBrowse link
G Khsrp KH-type splicing regulatory protein involved_in ISO (PMID:26523989) BHF-UCL PMID:26523989 NCBI chrNW_004955495:3,183,083...3,194,356
Ensembl chrNW_004955495:3,183,179...3,193,376 		JBrowse link
G Ldlr low density lipoprotein receptor involved_in ISO (PMID:17452316) ComplexPortal PMID:17452316 NCBI chrNW_004955495:2,114,702...2,135,584
Ensembl chrNW_004955495:2,114,434...2,138,056 		JBrowse link
G Mylip myosin regulatory light chain interacting protein involved_in ISO (MGI:3849777|PMID:19520913) BHF-UCL PMID:19520913 MGI:3849777 NCBI chrNW_004955483:9,725,343...9,745,041
Ensembl chrNW_004955483:9,723,023...9,745,062 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:17328821), (PMID:22848640) BHF-UCL PMID:17328821 PMID:22848640 NCBI chrNW_004955464:4,424,583...4,439,805
Ensembl chrNW_004955464:4,425,435...4,439,842 		JBrowse link
negative regulation of very-low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:1917954) BHF-UCL PMID:1917954 NCBI chrNW_004955555:2,005,962...2,007,239 JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO (PMID:1917954) BHF-UCL PMID:1917954 NCBI chrNW_004955555:2,019,547...2,021,543
Ensembl chrNW_004955555:2,016,217...2,021,830 		JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:1917954) BHF-UCL PMID:1917954 NCBI chrNW_004955412:18,165,667...18,168,015
Ensembl chrNW_004955412:18,165,667...18,168,015 		JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 involved_in ISO (PMID:8083232) BHF-UCL PMID:8083232 NCBI chrNW_004955514:2,195,228...2,208,258
Ensembl chrNW_004955514:2,195,228...2,208,688 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12321
    multicellular organismal process 6176
      plasma lipoprotein particle clearance 35
        negative regulation of lipoprotein particle clearance 11
          negative regulation of high-density lipoprotein particle clearance 1
          negative regulation of low-density lipoprotein particle clearance 8
          negative regulation of very-low-density lipoprotein particle clearance 4
Path 2
Term Annotations click to browse term
  biological_process 12321
    biological regulation 8863
      regulation of biological process 8603
        regulation of plasma lipoprotein particle levels 65
          plasma lipoprotein particle clearance 35
            regulation of lipoprotein particle clearance 20
              negative regulation of lipoprotein particle clearance 11
                negative regulation of high-density lipoprotein particle clearance 1
                negative regulation of low-density lipoprotein particle clearance 8
                negative regulation of very-low-density lipoprotein particle clearance 4
paths to the root