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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of lipoprotein particle clearance
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Accession:GO:0010985 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.



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negative regulation of high-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc3 apolipoprotein C3 involved_in IBA
ISO
PMID:21873635
(PMID:15778093)
RGD PMID:15778093 PMID:21873635 RGD:13792537 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Mir185 microRNA 185 involved_in ISO (PMID:23459944) RGD PMID:23459944 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795
JBrowse link
G Mir223 microRNA 223 involved_in ISO (PMID:23459944) RGD PMID:23459944 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996
JBrowse link
G Mir96 microRNA 96 involved_in ISO (PMID:23459944) RGD PMID:23459944 NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516
JBrowse link
negative regulation of low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 IMP RGD PMID:23828271 RGD:12792253 NCBI chr 1:96,598,663...96,679,495
Ensembl chr 1:96,598,647...96,679,510
JBrowse link
G Apoc3 apolipoprotein C3 involved_in IBA
ISO
PMID:21873635
(PMID:15778093)
RGD PMID:15778093 PMID:21873635 RGD:13792537 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Csk C-terminal Src kinase IDA RGD PMID:10884975 RGD:5134370 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292
JBrowse link
G Il19 interleukin 19 involved_in ISO (MGI:6102526|PMID:28257760) RGD PMID:28257760 MGI:6102526 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473
JBrowse link
G Khsrp KH-type splicing regulatory protein involved_in ISO RNAcentral:URS00004176D4_9606 (PMID:26523989) RGD PMID:26523989 NCBI chr 9:1,862,555...1,872,301
Ensembl chr 9:1,862,899...1,872,451
JBrowse link
G Ldlr low density lipoprotein receptor involved_in ISO (PMID:17452316) RGD PMID:17452316 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Mir133a1 microRNA 133a-1 involved_in ISO (PMID:28257760) RGD PMID:28257760 NCBI chr18:1,885,082...1,885,168 JBrowse link
G Mir148a microRNA 148a involved_in ISO (PMID:26437365) RGD PMID:26437365 NCBI chr 4:80,333,762...80,333,858
Ensembl chr 4:80,333,762...80,333,858
JBrowse link
G Mir17 microRNA 17 involved_in ISO (PMID:23285084) RGD PMID:23285084 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
JBrowse link
G Mir185 microRNA 185 acts_upstream_of
involved_in
ISO RNAcentral:URS00002367FA_9606|RNAcentral:URS00004176D4_9606 (PMID:24296663)
(PMID:26523989)
RGD PMID:24296663 PMID:26523989 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795
JBrowse link
G Mir199a2 microRNA 199a-2 involved_in ISO (PMID:26163491) RGD PMID:26163491 NCBI chr13:74,582,954...74,583,063
Ensembl chr13:74,582,954...74,583,063
JBrowse link
G Mir27a microRNA 27a involved_in ISO (PMID:26318398) RGD PMID:26318398 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917
JBrowse link
G Mir27b microRNA 27b involved_in ISO (PMID:26520906) RGD PMID:26520906 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529
JBrowse link
G Mir3582 microRNA 3582 involved_in ISO (PMID:28257760) RGD PMID:28257760 NCBI chr18:1,885,063...1,885,180
Ensembl chr18:1,885,063...1,885,180
JBrowse link
G Mylip myosin regulatory light chain interacting protein involved_in ISO (MGI:3849777|PMID:19520913) RGD PMID:19520913 MGI:3849777 NCBI chr17:19,286,649...19,308,295
Ensembl chr17:19,286,650...19,308,295
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:17328821), (PMID:22848640)
(PMID:17452316)
RGD PMID:17328821 PMID:17452316 PMID:22848640 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
JBrowse link
negative regulation of very-low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in IBA
ISO
PMID:21873635
(PMID:1917954)
RGD PMID:1917954 PMID:21873635 RGD:13792537 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375
JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO
IBA
(PMID:1917954)
PMID:21873635
RGD PMID:1917954 PMID:21873635 RGD:13792537 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476
JBrowse link
G Apoc3 apolipoprotein C3 involved_in IBA
ISO
PMID:21873635
(PMID:1917954)
RGD PMID:1917954 PMID:21873635 RGD:13792537 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 involved_in ISO
IBA
(PMID:8083232)
PMID:21873635
RGD PMID:8083232 PMID:21873635 RGD:13792537 NCBI chr14:75,651,371...75,663,380
Ensembl chr14:75,651,376...75,665,414
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    multicellular organismal process 9179
      plasma lipoprotein particle clearance 49
        negative regulation of lipoprotein particle clearance 21
          negative regulation of high-density lipoprotein particle clearance 4
          negative regulation of low-density lipoprotein particle clearance 16
          negative regulation of very-low-density lipoprotein particle clearance 4
Path 2
Term Annotations click to browse term
  biological_process 19738
    biological regulation 13436
      regulation of biological process 13021
        regulation of plasma lipoprotein particle levels 81
          plasma lipoprotein particle clearance 49
            regulation of lipoprotein particle clearance 31
              negative regulation of lipoprotein particle clearance 21
                negative regulation of high-density lipoprotein particle clearance 4
                negative regulation of low-density lipoprotein particle clearance 16
                negative regulation of very-low-density lipoprotein particle clearance 4
paths to the root