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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of mitotic sister chromatid separation
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Accession:GO:0010965 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis.


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regulation of mitotic sister chromatid separation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TPR translocated promoter region, nuclear basket protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:127,481,678...127,540,393
Ensembl chr 9:127,481,684...127,540,398 		JBrowse link
deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAD1L1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:19010891) UniProt PMID:19010891 NCBI chr 3:1,236,066...1,559,346
Ensembl chr 3:1,236,076...1,559,041 		JBrowse link
G MAD2L1BP MAD2L1 binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:38,613,349...38,623,845
Ensembl chr 7:38,613,440...38,623,832 		JBrowse link
G PRAP1 proline rich acidic protein 1 involved_in ISO (PMID:24374861) UniProt PMID:24374861 NCBI chr14:141,325,965...141,329,955 JBrowse link
mitotic spindle assembly checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APC APC regulator of WNT signaling pathway acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:17227893) MGI
Ensembl		 PMID:17227893 GO_REF:0000107 NCBI chr 2:116,913,354...116,985,303
Ensembl chr 2:116,812,582...117,034,887 		JBrowse link
G ATM ATM serine/threonine kinase involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:36,620,656...36,759,555
Ensembl chr 9:36,620,658...36,759,552 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 involved_in ISS UniProt GO_REF:0000024 NCBI chr12:3,747,276...3,755,214
Ensembl chr12:3,747,279...3,755,215 		JBrowse link
G BUB1 BUB1 mitotic checkpoint serine/threonine kinase involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:45,585,188...45,623,240
Ensembl chr 3:45,585,226...45,624,543 		JBrowse link
G BUB1B BUB1 mitotic checkpoint serine/threonine kinase B involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:131,093,026...131,143,840
Ensembl chr 1:131,092,958...131,143,794 		JBrowse link
G BUB3 BUB3 mitotic checkpoint protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:132,703,088...132,715,353
Ensembl chr14:132,703,725...132,715,348 		JBrowse link
G CENPE centromere protein E involved_in ISO (MGI:2673075|PMID:12925705) UniProt PMID:12925705 MGI:2673075 NCBI chr 8:117,888,968...117,965,325
Ensembl chr 8:117,888,970...117,965,252 		JBrowse link
G HASPIN histone H3 associated protein kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:49,820,435...49,823,515
Ensembl chr12:49,820,526...49,822,873 		JBrowse link
G IK IK cytokine involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:142,361,134...142,376,335
Ensembl chr 2:142,361,155...142,376,333 		JBrowse link
G KHDC3L KH domain containing 3 like, subcortical maternal complex member acts_upstream_of_or_within ISO (PMID:19376971) MGI PMID:19376971 NCBI chr 1:52,996,706...52,999,074 JBrowse link
G KLHL22 kelch like family member 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:50,773,917...50,809,991
Ensembl chr14:50,773,964...50,809,986 		JBrowse link
G KNTC1 kinetochore associated 1 involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr14:30,154,918...30,241,988
Ensembl chr14:30,153,702...30,241,829 		JBrowse link
G MAD1L1 mitotic arrest deficient 1 like 1 involved_in IEA
IBA		 InterPro
GO_Central
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:1,236,066...1,559,346
Ensembl chr 3:1,236,076...1,559,041 		JBrowse link
G MAD2L1 mitotic arrest deficient 2 like 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:11201745) Ensembl
MGI
GO_Central
TreeGrafter		 PMID:11201745 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:103,927,358...103,936,669
Ensembl chr 8:103,927,353...103,936,664 		JBrowse link
G PLK1 polo like kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:22,537,814...22,550,901
Ensembl chr 3:22,537,831...22,552,380 		JBrowse link
G PRODH2 proline dehydrogenase 2 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 6:45,213,712...45,240,437 JBrowse link
G PSMG2 proteasome assembly chaperone 2 acts_upstream_of_or_within ISO (PMID:12147697) MGI PMID:12147697 NCBI chr 6:96,879,009...96,893,551
Ensembl chr 6:96,878,139...96,893,474 		JBrowse link
G SPDL1 spindle apparatus coiled-coil protein 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr16:54,276,943...54,303,465
Ensembl chr16:54,277,052...54,303,544 		JBrowse link
G TEX14 testis expressed 14, intercellular bridge forming factor involved_in IEA
IBA		 InterPro
TreeGrafter
GO_Central
Ensembl		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr12:34,815,472...34,975,901
Ensembl chr12:34,815,476...34,912,766 		JBrowse link
G TPR translocated promoter region, nuclear basket protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:127,481,678...127,540,393
Ensembl chr 9:127,481,684...127,540,398 		JBrowse link
G TRIP13 thyroid hormone receptor interactor 13 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:79,458,843...79,473,705
Ensembl chr16:79,458,847...79,473,712 		JBrowse link
G TTK TTK protein kinase involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:86,076,576...86,125,334
Ensembl chr 1:86,076,583...86,125,718 		JBrowse link
G ZNF207 zinc finger protein 207 involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr12:42,576,534...42,602,789
Ensembl chr12:42,576,532...42,612,396 		JBrowse link
G ZW10 zw10 kinetochore protein involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:41,358,801...41,400,254
Ensembl chr 9:41,348,896...41,400,208 		JBrowse link
G ZWILCH zwilch kinetochore protein involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter
UniProt		 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:164,481,784...164,526,843
Ensembl chr 1:164,481,964...164,527,223 		JBrowse link
G ZWINT ZW10 interacting kinetochore protein involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr14:94,094,781...94,109,447
Ensembl chr14:94,094,894...94,102,060 		JBrowse link
negative regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXO5 F-box protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:13,466,961...13,478,496
Ensembl chr 1:13,467,501...13,505,928 		JBrowse link
G RAD21 RAD21 cohesin complex component involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:21,772,821...21,802,453
Ensembl chr 4:21,772,855...21,802,715 		JBrowse link
G USP44 ubiquitin specific peptidase 44 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:87,864,410...87,890,913
Ensembl chr 5:87,875,851...87,889,680 		JBrowse link
positive regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DYNC1LI1 dynein cytoplasmic 1 light intermediate chain 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:18,507,710...18,558,057
Ensembl chr13:18,506,194...18,558,007 		JBrowse link
G GEN1 GEN1 Holliday junction 5' flap endonuclease involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:120,067,792...120,097,305
Ensembl chr 3:120,065,973...120,097,056 		JBrowse link
G MAD1L1 mitotic arrest deficient 1 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:1,236,066...1,559,346
Ensembl chr 3:1,236,076...1,559,041 		JBrowse link
G MAD2L1 mitotic arrest deficient 2 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:103,927,358...103,936,669
Ensembl chr 8:103,927,353...103,936,664 		JBrowse link
G NDC80 NDC80 kinetochore complex component involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:104,000,794...104,055,785
Ensembl chr 6:103,999,034...104,055,760 		JBrowse link
G PCID2 PCI domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:78,541,278...78,556,784
Ensembl chr11:78,541,318...78,556,733 		JBrowse link
G TPR translocated promoter region, nuclear basket protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:127,481,678...127,540,393
Ensembl chr 9:127,481,684...127,540,398 		JBrowse link
G XRCC3 X-ray repair cross complementing 3 involved_in IEA Ensembl GO_REF:0000107
positive regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANAPC11 anaphase promoting complex subunit 11 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:1,095,091...1,099,233 JBrowse link
G ANAPC5 anaphase promoting complex subunit 5 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr14:31,259,695...31,306,434
Ensembl chr14:31,259,727...31,306,441 		JBrowse link
G ANAPC7 anaphase promoting complex subunit 7 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr14:31,744,729...31,789,750
Ensembl chr14:31,763,243...31,789,750 		JBrowse link
G CDC16 cell division cycle 16 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr11:79,084,243...79,111,758
Ensembl chr11:79,084,182...79,115,268 		JBrowse link
G CDC20 cell division cycle 20 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:167,886,266...167,890,587
Ensembl chr 6:167,886,270...167,890,583 		JBrowse link
G CDC23 cell division cycle 23 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:140,211,334...140,245,728
Ensembl chr 2:140,211,331...140,230,789 		JBrowse link
G CENPE centromere protein E involved_in ISO (MGI:2673075|PMID:12925705) UniProt PMID:12925705 MGI:2673075 NCBI chr 8:117,888,968...117,965,325
Ensembl chr 8:117,888,970...117,965,252 		JBrowse link
G CUL3 cullin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:126,191,605...126,287,148
Ensembl chr15:126,189,851...126,287,005 		JBrowse link
G NSMCE2 NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:14,359,323...14,598,192
Ensembl chr 4:14,358,651...14,598,077 		JBrowse link
G RB1 RB transcriptional corepressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:19,186,754...19,317,642
Ensembl chr11:19,186,761...19,317,690 		JBrowse link
G UBE2C ubiquitin conjugating enzyme E2 C involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:48,018,403...48,021,542
Ensembl chr17:48,018,400...48,021,534 		JBrowse link
regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANAPC15 anaphase promoting complex subunit 15 involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:6,685,934...6,689,913
Ensembl chr 9:6,685,939...6,689,256 		JBrowse link
G CCNB1 cyclin B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:47,338,239...47,348,385
Ensembl chr16:47,338,110...47,348,377 		JBrowse link
G CDK5RAP2 CDK5 regulatory subunit associated protein 2 involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:260,465,809...260,648,070
Ensembl chr 1:260,466,942...260,648,161 		JBrowse link
G KNL1 kinetochore scaffold 1 involved_in ISO (PMID:19893618) UniProt PMID:19893618 NCBI chr 1:130,652,493...130,728,989 JBrowse link
G LCMT1 leucine carboxyl methyltransferase 1 acts_upstream_of_or_within ISO (PMID:17724024) MGI PMID:17724024 NCBI chr 3:21,548,349...21,593,667 JBrowse link
G PRP4K pre-mRNA processing factor kinase PRP4K involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:2,382,498...2,417,085
Ensembl chr 7:2,382,495...2,412,908 		JBrowse link
G USP44 ubiquitin specific peptidase 44 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:87,864,410...87,890,913
Ensembl chr 5:87,875,851...87,889,680 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17813
    cellular process 16883
      cell cycle process 1314
        mitotic cell cycle process 770
          mitotic sister chromatid separation 55
            regulation of mitotic sister chromatid separation 52
              negative regulation of mitotic sister chromatid separation + 42
              positive regulation of mitotic sister chromatid separation + 14
              regulation of mitotic cell cycle spindle assembly checkpoint + 17
              regulation of mitotic sister chromatid arm separation + 0
Path 2
Term Annotations click to browse term
  biological_process 17813
    cellular process 16883
      cellular component organization or biogenesis 6721
        cellular component organization 6506
          organelle organization 3624
            organelle fission 533
              nuclear division 477
                mitotic nuclear division 278
                  mitotic sister chromatid segregation 187
                    mitotic sister chromatid separation 55
                      regulation of mitotic sister chromatid separation 52
                        negative regulation of mitotic sister chromatid separation + 42
                        positive regulation of mitotic sister chromatid separation + 14
                        regulation of mitotic cell cycle spindle assembly checkpoint + 17
                        regulation of mitotic sister chromatid arm separation + 0
paths to the root