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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of mitotic sister chromatid separation
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Accession:GO:0010965 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis.


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regulation of mitotic sister chromatid separation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TPR translocated promoter region, nuclear basket protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:161,842,037...161,903,567
Ensembl chr 1:165,993,726...166,055,223 		JBrowse link
deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAD1L1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:19010891) UniProt PMID:19010891 NCBI chr 7:2,070,299...2,502,471
Ensembl chr 7:2,187,104...2,601,328 		JBrowse link
G MAD2L1BP MAD2L1 binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:43,219,638...43,230,988
Ensembl chr 6:44,509,839...44,521,590 		JBrowse link
G PRAP1 proline rich acidic protein 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr10:134,248,728...134,268,442 JBrowse link
mitotic spindle assembly checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APC APC regulator of WNT signaling pathway acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:17227893) MGI
Ensembl		 PMID:17227893 GO_REF:0000107 NCBI chr 5:108,070,697...108,208,273
Ensembl chr 5:113,904,352...114,009,709 		JBrowse link
G ATM ATM serine/threonine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 involved_in ISO (PMID:12805209) UniProt PMID:12805209 NCBI chr17:72,292,332...72,303,493
Ensembl chr17:77,842,724...77,854,159 		JBrowse link
G BUB1 BUB1 mitotic checkpoint serine/threonine kinase involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr2A:91,393,317...91,433,579
Ensembl chr2A:111,793,236...111,858,392 		JBrowse link
G BUB1B BUB1 mitotic checkpoint serine/threonine kinase B involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr15:19,095,383...19,155,557
Ensembl chr15:37,350,826...37,410,648 		JBrowse link
G BUB3 BUB3 mitotic checkpoint protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:119,712,244...119,723,410
Ensembl chr10:123,987,541...123,998,011 		JBrowse link
G CENPE centromere protein E involved_in ISO (MGI:2673075|PMID:12925705) UniProt PMID:12925705 MGI:2673075 NCBI chr 4:95,562,005...95,654,397
Ensembl chr 4:106,185,283...106,277,229 		JBrowse link
G HASPIN histone H3 associated protein kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:3,772,899...3,775,903
Ensembl chr17:3,767,404...3,769,800 		JBrowse link
G IK IK cytokine involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:136,012,381...136,027,099
Ensembl chr 5:142,129,130...142,143,393 		JBrowse link
G KHDC3L KH domain containing 3 like, subcortical maternal complex member acts_upstream_of_or_within ISO (PMID:19376971) MGI PMID:19376971 NCBI chr 6:71,089,817...71,190,700
Ensembl chr 6:74,478,303...74,479,826 		JBrowse link
G KLHL22 kelch like family member 22 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr22:19,122,875...19,174,842 JBrowse link
G KNTC1 kinetochore associated 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:120,129,557...120,228,384
Ensembl chr12:124,351,508...124,448,624 		JBrowse link
G MAD1L1 mitotic arrest deficient 1 like 1 involved_in IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:2,070,299...2,502,471
Ensembl chr 7:2,187,104...2,601,328 		JBrowse link
G MAD2L1 mitotic arrest deficient 2 like 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11201745) Ensembl
MGI
TreeGrafter		 PMID:11201745 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:112,247,808...112,255,202
Ensembl chr 4:123,397,355...123,405,535 		JBrowse link
G PLK1 polo like kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:14,420,972...14,432,821
Ensembl chr16:23,928,773...23,940,779 		JBrowse link
G PSMG2 proteasome assembly chaperone 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12147697) Ensembl
MGI		 PMID:12147697 GO_REF:0000107 NCBI chr18:1,597,981...1,620,721
Ensembl chr18:16,713,534...16,735,531 		JBrowse link
G SPDL1 spindle apparatus coiled-coil protein 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:164,949,009...164,967,957
Ensembl chr 5:171,710,108...171,729,148 		JBrowse link
G TEX14 testis expressed 14, intercellular bridge forming factor involved_in IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr17:52,627,335...52,768,926
Ensembl chr17:57,480,369...57,621,055 		JBrowse link
G TPR translocated promoter region, nuclear basket protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:161,842,037...161,903,567
Ensembl chr 1:165,993,726...166,055,223 		JBrowse link
G TRIP13 thyroid hormone receptor interactor 13 involved_in ISO (PMID:28553959) UniProt PMID:28553959
G TTK TTK protein kinase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:77,887,382...77,925,737
Ensembl chr 6:81,158,143...81,196,478 		JBrowse link
G ZNF207 zinc finger protein 207 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:24,405,632...24,425,868
Ensembl chr17:24,690,903...24,714,628 		JBrowse link
G ZW10 zw10 kinetochore protein involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:108,611,818...108,652,444
Ensembl chr11:112,454,637...112,495,316 		JBrowse link
G ZWILCH zwilch kinetochore protein involved_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr15:45,452,382...45,496,780
Ensembl chr15:63,727,562...63,771,213 		JBrowse link
G ZWINT ZW10 interacting kinetochore protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:52,978,892...52,986,797
Ensembl chr10:55,202,383...55,206,450 		JBrowse link
negative regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXO5 F-box protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:150,793,020...150,806,008
Ensembl chr 6:155,481,753...155,494,231 		JBrowse link
G RAD21 RAD21 cohesin complex component involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:113,520,456...113,549,339
Ensembl chr 8:116,063,503...116,092,421 		JBrowse link
G USP44 ubiquitin specific peptidase 44 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:93,111,293...93,146,889
Ensembl chr12:96,503,794...96,536,094 		JBrowse link
positive regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DYNC1LI1 dynein cytoplasmic 1 light intermediate chain 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:32,450,693...32,495,400
Ensembl chr 3:32,758,407...32,804,117 		JBrowse link
G GEN1 GEN1 Holliday junction 5' flap endonuclease involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:17,735,953...17,766,018
Ensembl chr2A:17,862,070...17,892,048 		JBrowse link
G MAD1L1 mitotic arrest deficient 1 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:2,070,299...2,502,471
Ensembl chr 7:2,187,104...2,601,328 		JBrowse link
G MAD2L1 mitotic arrest deficient 2 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:112,247,808...112,255,202
Ensembl chr 4:123,397,355...123,405,535 		JBrowse link
G NDC80 NDC80 kinetochore complex component involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:11,666,099...11,711,456
Ensembl chr18:13,972,637...14,018,261 		JBrowse link
G PCID2 PCI domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:94,319,699...94,350,763
Ensembl chr13:113,388,251...113,419,251 		JBrowse link
G TPR translocated promoter region, nuclear basket protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:161,842,037...161,903,567
Ensembl chr 1:165,993,726...166,055,223 		JBrowse link
G XRCC3 X-ray repair cross complementing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:84,323,644...84,341,763
Ensembl chr14:104,131,903...104,149,037 		JBrowse link
positive regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANAPC11 anaphase promoting complex subunit 11 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:76,297,262...76,305,826
Ensembl chr17:82,002,135...82,007,921 		JBrowse link
G ANAPC5 anaphase promoting complex subunit 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:118,906,482...118,950,913
Ensembl chr12:122,279,227...122,324,428 		JBrowse link
G ANAPC7 anaphase promoting complex subunit 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:107,946,756...107,977,489
Ensembl chr12:111,338,045...111,368,466 		JBrowse link
G CDC16 cell division cycle 16 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:95,300,763...95,340,762
Ensembl chr13:114,369,774...114,407,267 		JBrowse link
G CDC20 cell division cycle 20 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:42,660,338...42,664,618
Ensembl chr 1:44,039,971...44,044,497 		JBrowse link
G CDC23 cell division cycle 23 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:133,566,022...133,591,528
Ensembl chr 5:139,699,421...139,724,991 		JBrowse link
G CENPE centromere protein E involved_in ISO (MGI:2673075|PMID:12925705) UniProt PMID:12925705 MGI:2673075 NCBI chr 4:95,562,005...95,654,397
Ensembl chr 4:106,185,283...106,277,229 		JBrowse link
G CUL3 cullin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:111,714,533...111,827,080
Ensembl chr2B:230,289,195...230,378,991 		JBrowse link
G NSMCE2 NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:121,777,986...122,052,094
Ensembl chr 8:124,529,268...124,803,114 		JBrowse link
G RB1 RB transcriptional corepressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:29,453,872...29,624,665
Ensembl chr13:48,155,795...48,324,575 		JBrowse link
G UBE2C ubiquitin conjugating enzyme E2 C involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:42,152,219...42,156,246
Ensembl chr20:43,239,382...43,243,464 		JBrowse link
regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANAPC15 anaphase promoting complex subunit 15 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr11:67,186,653...67,193,102
Ensembl chr11:70,411,031...70,416,484 		JBrowse link
G CCNB1 cyclin B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:44,826,103...44,836,832
Ensembl chr 5:46,394,362...46,405,332 		JBrowse link
G CDK5RAP2 CDK5 regulatory subunit associated protein 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:91,519,179...91,707,469
Ensembl chr 9:119,868,015...120,055,608 		JBrowse link
G KNL1 kinetochore scaffold 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:19,539,264...19,609,593
Ensembl chr15:37,801,705...37,860,858 		JBrowse link
G LCMT1 leucine carboxyl methyltransferase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:17724024) MGI
Ensembl		 PMID:17724024 GO_REF:0000107 Ensembl chr16:25,351,814...25,418,285 JBrowse link
G LOC100989277 anaphase-promoting complex subunit 15-like involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr  X:1,374,844...1,375,700 JBrowse link
G PRP4K pre-mRNA processing factor kinase PRP4K involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:3,854,844...3,898,185
Ensembl chr 6:4,044,610...4,085,148 		JBrowse link
G USP44 ubiquitin specific peptidase 44 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:93,111,293...93,146,889
Ensembl chr12:96,503,794...96,536,094 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    cellular process 15499
      cell cycle process 1277
        mitotic cell cycle process 745
          mitotic sister chromatid separation 55
            regulation of mitotic sister chromatid separation 52
              negative regulation of mitotic sister chromatid separation + 42
              positive regulation of mitotic sister chromatid separation + 14
              regulation of mitotic cell cycle spindle assembly checkpoint + 18
              regulation of mitotic sister chromatid arm separation + 0
Path 2
Term Annotations click to browse term
  biological_process 16440
    cellular process 15499
      cellular component organization or biogenesis 6620
        cellular component organization 6401
          organelle organization 3612
            organelle fission 527
              nuclear division 473
                mitotic nuclear division 278
                  mitotic sister chromatid segregation 191
                    mitotic sister chromatid separation 55
                      regulation of mitotic sister chromatid separation 52
                        negative regulation of mitotic sister chromatid separation + 42
                        positive regulation of mitotic sister chromatid separation + 14
                        regulation of mitotic cell cycle spindle assembly checkpoint + 18
                        regulation of mitotic sister chromatid arm separation + 0
paths to the root